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Water contamination with per- and polyfluoroalkyl substances (PFAS) is a serious problem for water suppliers in many regions. Due to persistence of the substances and a complex distribution mechanism, PFAS can have an adverse impact on water quality. Reported toxicological and health effects, make it very important to minimise the of wildlife and human exposure to PFAS. The exposure path is, howev
Knowledge, when used effectively, is a major input for development. However, the processes associated with knowledge production, knowledge transfer, and knowledge use are complex and not easy to facilitate in certain parts of the world. This is mainly due to a lack of or limited interactions between knowledge producers and knowledge users. This thesis aims to explore how efforts to foster knowledg
Several pharmacogenetics studies have identified an association between a greater metformin-dependent reduction in HbA1c levels and the minor A allele at rs2289669 in intron 10 of SLC47A1, encoding multidrug and toxin extrusion 1 (MATE1), a presumed metformin transporter. It is currently unknown if the rs2289669 locus is a cis-eQTL, which would validate its role as predictor of metformin efficacy.
The challenges of sustainable development require whole supply chains and networks to drive change and innovation. However, most existing research on sustainable innovations is on a company level and the dominating company focus in practice drives “silo” approaches, short-term thinking, and profit maximization. Consequently, there is a need for research and new models that facilitate sustainable sThe challenges of sustainable development require whole supply chains and networks to drive change and innovation. However, most existing research on sustainable innovations is on a company level and the dominating company focus in practice drives “silo” approaches, short-term thinking, and profit maximization. Consequently, there is a need for research and new models that facilitate sustainable s
The use of radio signal for position tracking (positioning) and navigation has a long tradition. Most notably, global navigation satellite systems (GNSS) are now widely applied for civilian applications, ranging all the way from tracking of cargo containers to gaming. However, GNSS suffers from limited coverage in dense urban areas and indoors and also from a limited position accuracy, which rules
Production of a protein of interest in bacteria and its purification from bacterial lysates are valuable tools for the purification of larger amounts of recombinant proteins. The low cost of culturing, and the rapid cell growth of bacteria make this host a good choice for protein production, but the folding and function of the purified protein might be altered due to the production of a eukaryotic
Information and communication technology (ICT) is ubiquitous in tourism and this changes not only tourists’ immediate behaviour, but also what tourism is. In this way, digitalisation is shifting perceptions of when tourism starts and ends, and how we can understand the term in principal ways. The aim of this working paper is to contribute to the debate about the consequences of today´s fast digita
Transitions in medical education are moments of intense learning, bringing significant challenges for the trainees, the medical programs and healthcare provision. Frequently, transitional periods are not prepared or mentored; this process of transformation in the trainee is left to occur by chance and opportunity. Promotion of medical education continuity requires formal support in the continuous
Supercapacitive biofuel cells’ (SBFCs) most recent advancements are herein disclosed. In conventional SBFCs the biocomponent is employed as the pseudocapacitive component, while in self-charging biodevices it also works as the biocatalyst. The performance of different types of SBFCs are summarized according to the categorization based on the biocatalyst employed: supercapacitive microbial fuel cel
Cancer cells hijack developmental growth mechanisms but whether tissue morphogenesis and architecture modify tumorigenesis is unknown. Here, we characterized a new mouse model of sporadic thyroid carcinogenesis based on inducible expression of BRAF carrying a Val600 Glu (V600E) point mutation (BRAFV600E) from the thyroglobulin promoter (TgCreERT2). Spontaneous activation of this Braf-mutant allele
Background: To engage people who inject drugs (PWID) in HCV care, innovative models of care are urgently needed. A needle exchange program (NEP) could serve as an ideal platform for comprehensive HCV management including post treatment follow up. Methods: 50 actively injecting patients at the Malmö Needle exchange program (MNEP) were consecutively enrolled between April 2018 and May 2019. All pati
Soil moisture can strongly affect the fate of soil organic carbon (C) during microbial decomposition, but the characterisation and prediction of the effects remain challenging, especially the long-term effects of drought history and its interaction with current levels of soil moisture. We investigated the legacy effects of drought on soil activity and microbial community composition and its intera
Elevated arsenic (As) in soil is of public concern due to the carcinogenicity. Phosphorus (P) strongly influences the adsorption, absorption, transport, and transformation of As in the soil and in organisms due to the similarity of the chemical properties of P and As. In soil, P, particularly inorganic P, can release soil-retained As (mostly arsenate) by competing for adsorption sites. In plant an
