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The hypothalamus and sex hormones are closely linked to primary headache disorders. Migraine is the most prevalent disabling neurological disorder, affecting up to 15% of the global population, with enormous socioeconomic and personal impacts. It ranks second among years lived with disability (YLD), with women being the most affected, experiencing a threefold higher prevalence than men. Women repo
This study explores causes for uncertainty that social workers experience when making assessments ofout of home placements in foster or institutional care. Uncertainty is often considered to be an integralpart of professional decision making, and the reason why professions are needed at all. Most researchhas concentrated on investigating how uncertainty is approached in education, professions, and
We present an extension of the SPL-BEV (Soccer Player Localization for Bird’s-Eye-View) method, introducing Decomposable Tiled SPL-BEV (DTSPL-BEV), a variant designed to enable efficient inference on embedded devices. We show specialized tiling algorithms that enable inference on a given devices with some known memory limitations, while also ensuring the same detection results as running inference
This article examines the emerging migration corridor between Uzbekistan and Sweden based on interviews, focus groups, and data from a survey conducted in both countries in 2024. Although small in scale, this corridor is analytically significant for understanding the diversification of Uzbek migration beyond Russia and Turkey. Findings show that demographic pressures, limited employment, and envir
Thermal performance curves (TPCs) capture how population growth depends on temperature. When temperatures increase, such as during global change, TPCs may evolve to match new environmental temperatures. While previous studies mostly focus on population growth rate TPCs, evolution can also be strongly trait-dependent and require a multi-trait analysis. Here, we empirically tested how TPCs and multi
En växande grupp barn och unga i Sverige uppvisar skolvägran och ökande psykisk ohälsa, ofta i kombination med höga krav, otillräckligt stöd och svårigheter att hantera skolvardagen. Skolsköterskan har en central roll i tidig upptäckt och stöd, men saknar i dag gemensamma arbetssätt och språk för att aktivt bidra till elevernas återgång till skolan. Därför söker vi skolsköterskor med minst två års
Mannosyl β-C-1 amidotriazoles have previously been reported to have higher selectivity for galectin-9N (N-terminal domain) than the corresponding galactoside C3 amidotriazoles have, which were more selective for galectin-3. This study further investigated this by synthesis of mono- and bis-aryltriazolyl mannoside analogues to known high-affinity galectin-3 galactosyl-derived inhibitors. Following
Target cell entry of HIV-1 is dependent on the binding of gp120, the outer component of the viral envelope glycoprotein complex (Env), to CD4 and a coreceptor, preferentially CCR5 or CXCR4. Still, other interactions may also contribute to the infectivity of the virus. One such interaction is between the highly glycosylated gp120 and carbohydrate-binding proteins, such as galectins. Here, we studie
The pressure to design, develop and implement systems that exploit the potential of technological innovation in effective and efficient ways that contribute to the organisational goals never ceases. Post 1945 industrialisation evolved from mechanisation of industrial processes through to computerisation to the age of digitalisation and beyond. From the study of mechanisation of work in coal mining
This chapter discusses trade-offs that need to be struck while developing Unmanned Aircraft Systems (UAS) operations. Ten trade-offs are outlined, pertaining to technical systems, to human operators, and to the combined sociotechnical system in its operational and organizational environment, which have implications for Human-Systems Integration (HSI) in multiple phases of the systems engineering l
BACKGROUND: The incidence of postoperative pulmonary complications (PPCs3) following abdominal surgery varies across surgical specialties. It remains unclear to what extent the incidence of PPCs is attributable to known patient-related factors and anaesthesia duration, rather than to differences inherent to the surgical specialty itself.METHODS: Post-hoc analysis of an observational study describi
IntroductionForensic assessments of whether an injury would have been life-threatening often rely on empirical knowledge rather than evidence-based criteria. To address this gap, we applied the validated trauma scoring system New Injury Severity Score (NISS) to estimate mortality risk along the natural course of single stab injuries to the trunk.Methods and materialsWe included 408 survivors and 1
This chapter examines the Iranian state-produced film The Golden Collars as a tool of regime propaganda, focusing on how it constructs narratives of heroes and villains within the context of the 2009 post-election protests. It shows how the Islamic Republic, through state media, portrays foreign intelligence services—particularly those of the United States, United Kingdom, and Israel—as orchestrat
Current strategies to reduce the climate impact of production and consumption are insufficient to meet the pressing targets of the Paris Agreement. To expand visions of the possible ‘solution space’ in climate transitions, we explore a framework based on two dichotomies centred around the role of labour and the composition of economic output. From these dichotomies we sketch out four pathways for
Whereas the link between impaired male fertility and risk of testicular and prostate cancer is well established, studies investigating non-reproductive cancer risk among men with impaired reproductive function are scarce and show conflicting results. The aim of the study was to compare the risk of developing non-reproductive cancers in men achieving paternity through assisted reproduction as compa
INTRODUCTION: Intracranial haemorrhage (ICH) is the most serious complication in infants and children with severe congenital bleeding disorders causing substantial mortality and long-term neurological morbidity. The neonatal period carries the highest risk, particularly in severe haemophilia and rare factor deficiencies. We review the epidemiology, risk factors, prevention, recognition, management
BACKGROUND: There is limited information concerning the current practice of intraoperative mechanical ventilation in obese patients, and the optimal ventilator settings for these patients are debated. We investigated intraoperative ventilation parameters and their associations with the development of postoperative pulmonary complications (PPCs) in obese patients.METHODS: We performed a secondary a
Background: Anaemia is frequently recorded during preoperative screening and has been suggested to affect outcomes after surgery negatively.Objectives: The objectives were to assess the frequency of moderate to severe anaemia and its association with length of hospital stay.Design: Post hoc analysis of the international observational prospective 'Local ASsessment of VEntilatory management during G
