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Plant defense responses are mediated by hormones such as jasmonic acid (JA) and salicylic acid (SA). JA and SA are known to trigger a range of different defense responses in model plants but little is described in crops like quinoa. Here, we present the first molecular description of JA and SA signaling at the transcriptomic level in quinoa. The transcriptomes of quinoa cv. Kurmi seedlings treated
Besides their central function in respiration, plant mitochondria play a crucial role in maintaining cellular homeostasis during stress by providing "retrograde" feedback to the nucleus. Despite the growing understanding of this signaling network, the nature of the signals that initiate mitochondrial retrograde regulation (MRR) in plants remains unknown. Here, we investigated the dynamics and caus
The use of Large Language Models (LLMs) such as ChatGPT is a prominent topicin higher education, prompting debate over their educational impact. Studies onthe effect of LLMs on learning in higher education often rely on self-reported data,leaving an opening for complimentary methodologies. This study contributes byanalysing actual course grades as well as ratings by fellow students to investigateh
The interdisciplinary nature of microbiome research, coupled with the generation of complex multi-omics data, makes knowledge sharing challenging. The Strengthening the Organization and Reporting of Microbiome Studies (STORMS) guidelines provide a checklist for the reporting of study information, experimental design and analytical methods within a scientific manuscript on human microbiome research
L-DOPA-induced dyskinesia (LID) is a debilitating complication of dopamine replacement therapy in Parkinson's disease and the most common hyperkinetic disorder of basal ganglia origin. Abnormal activity of striatal D1 and D2 spiny projection neurons (SPNs) is critical for LID, yet the link between SPN activity patterns and specific dyskinetic movements remains unknown. To explore this, we implemen
Parkinson's disease (PD) is characterized by a set of motor symptoms that depend on nigrostriatal dopaminergic degeneration and respond well to pharmacological dopamine replacement using L-DOPA. However, replacing dopamine with either L-DOPA or dopamine receptor agonists leads to the appearance of motor and nonmotor complications within a few years. Strong emphasis is currently placed on developin
We present the development of a new colour reconnection model in Pythia where the full spacetime separation between partons constrains the reconnection probability throughout the final-state radiative shower. Building upon previous ideas of a perturbative dipole-based model, our objective is to introduce realistic spatially-based colour reconnections within the Angantyr model for heavy-ion collisi
Standard ZYMO DNA/RNA miniprep extraction protocol written in a user friendly way to reduce in-process-decisions and process time
l-DOPA-induced dyskinesia (LID) is a prevalent complication of dopamine replacement therapy in Parkinson’s disease. In addition to its clinical importance, LID represents a paradigm to unravel how altered signaling downstream of dopamine receptors can disrupt mechanisms of synaptic plasticity and motor information processing in the cortico-basal ganglia network. This chapter focuses on experimenta
The aim of this study was to perform histopathological reassessment of primary resections of locally advanced colon cancer (CC) within a randomized controlled trial, with specific focus on surgical margins and synchronous locoregional peritoneal metastases (SL-PM), and to provide learning points for both surgeons and pathologists. All histopathological slides of patients with c/pT4N0-2M0 or perfor
Modified ZYMO DNA/RNA miniprep extraction protocol written in a user friendly way to reduce in-process-decisions and process time. Sample type is organic soil, peat, from a degraded rich fenThis protocol includes two modifications to tackle clogged filters. Samples were centrifuged for 45 seconds instead of 30 seconds in first pass through filters as 100 ul to 200 ul sample remained trapped above
Boreal forests emit terpenoid biogenic volatile organic compounds (BVOCs) that significantly affect atmospheric chemistry. Our understanding of the variation of BVOC species emitted from boreal ecosystems is based on relatively few datasets, especially at the ecosystem-level. We conducted measurements to obtain BVOC flux observations above the boreal forest at the ICOS (Integrated Carbon Observati
Bryophytes constitute a diverse plant group with important roles in ecosystem functioning, in particular in arctic and subarctic environments. As they are physiologically strongly dependent on climatic conditions bryophytes could serve as indicators of ongoing climatic change. Their spores are generally dispersed by wind, and because of contrasting phenologies among species, the composition of the
BackgroundSome patients scheduled for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) only undergo explorative laparotomy (open/close procedure) due to extensive tumor spread or challenges in achieving complete cytoreduction (CC0). This study aimed to evaluate the surgical outcomes and overall survival in patients with peritoneal surface malignancy (PSM) who only
We recently published an article that demonstrates how eDNA can reveal shifts in the annual timing of wind-carried dispersal agents (spores) of mosses and liverworts.
This article assesses the determinants of intragenerational social mobility across occupational trajectories in Southern Europe, focusing on Catalonia (1880s–1950s). Using a novel longitudinal database of individuals born 1870–1909 in the Baix Llobregat area, we examine sibling correlations in occupational status as a proxy for family socioeconomic resemblance and trace career progression across e
A secondary objective of Bryomolecules is to apply methods developed in the project for what is known as ex situ preservation, that is, maintaining collections of endangered species in laboratory cultures. It is undoubtedly always best to preserve the species in their natural environment, but sometimes this is not enough. Lab cultures could potentially be used to replace populations that have gone
The scene floor of the forest theatre consists of a green mat of small plants. For most people it is quite anonymous and un-noticed, but several hundreds of species could thrive in this environment. In my research, I try to understand aspects of this hidden world of mosses and liverworts, including their relations to other plants and animals.
Viruses that infect single-celled algae strongly regulate microalgae growth and community composition through cell lysis, enable nutrient recycling in marine ecosystems, and offer valuable insights into early stages of viral evolution. One major group, the Bacilladnaviridae family of single-stranded DNA viruses, infects diatoms in marine environments. Here, we present the capsid structure of Ch
