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Magnetic resonance imaging (MRI) is the primary method for noninvasive investigations of the human brain in health, disease, and development but yields data that are difficult to interpret whenever the millimeter-scale voxels contain multiple microscopic tissue environments with different chemical and structural properties. We propose a novel MRI framework to quantify the microscopic heterogeneity
American photographer Jerry N. Uelsmann (1934–2022) was a seminal figure in photo history. Uelsmann catalyzed the transfer from modernist to post-modern photography with his at the time controversial photo montages and double exposures. Decades before the birth of digital image editing programs like Photoshop, Uelsmann created photo montages by combining several negatives in the darkroom. He start
Under covid-19-pandemin blev många anställda rekommenderade eller tvingade att arbeta på distans (Fackförbundet ST, 2020; Wang m.fl., 2021). Sammantaget arbetade 30–40 procent av arbetstagarna hela eller delar av sin arbetstid på distans under pandemin (Myndigheten för arbetsmiljökunskap, 2021). Den fysiska arbetsplatsen var inte längre en självklarhet; från en dag till en annan blev i stället dis
Dataspelsbranschen beskrivs som både en kulturell näring och som en del av tech-industrin. De olika beskrivningarna ger skilda associationer och illustrerar branschens många sidor. Det är också illustrativt för arbetet som spelutvecklare, vilket ofta beskrivs som en skärningspunkt mellan såväl konstnärligt arbete och teknik, som mellan kultur och kommers. I ett pågående forskningsprojekt om spelut
BACKGROUND/AIM: Opioid overdose deaths have increased in Sweden and other developed countries in recent decades, despite increased treatment efforts and harm-reduction interventions. Further knowledge in this field is needed if this trend is to be reversed. Previous research suggests that mental health and patterns of prescription of opioids and other prescription drugs are associated with increas
Non-negative matrix factorization (NMF) is a relatively new approach to analyze gene expression data that models data by additive combinations of non-negative basis vectors (metagenes). The non-negativity constraint makes sense biologically as genes may either be expressed or not, but never show negative expression. We applied NMF to five different microarray data sets. We estimated the appropriat
Streptococcus pyogenes causes a multitude of local and systemic infections, the most common being pharyngitis in children. Recurrent pharyngeal infections are common and are thought to be due to the re-emergence of intracellular GAS upon completion of antibiotic treatment. The role of colonizing biofilm bacteria in this process is not fully clear. Here, live respiratory epithelial cells were ino
Samtidigt som bilen är själva grunden för det sätt vi förflyttar oss i samhället, utgör bilismen den främsta orsaken till transportsektorns negativa miljö- och hälsoeffekter. Denna avhandling handlar om politiska försök att gå bortom bilen, mot en mer hållbar form av mobilitet. Hållbar mobilitet eller hållbara transporter, som är den mer använda termen i Sverige, har de senaste decennierna kommitTransport policies in Western Europe are increasingly framed in terms of sustainable mobility. This is a response to an urgent need to tackle adverse consequences of the transport system and implies changes in discourses related to transport. Exploring sustainable mobility is a fruitful way of studying discursive development in a policy field historically connected to priorities radically differen
Alveolar epithelial cells (AEC) have been implicated in pathological remodelling. We examined the capacity of AEC to produce extracellular matrix (ECM) and thereby directly contribute towards remodelling in chronic lung diseases. Cryopreserved type 2 AEC (AEC2) from healthy lungs and chronic obstructive pulmonary disease (COPD) afflicted lungs were cultured in decellularized healthy human lung sli
Nonlinear analysis of structures at high temperatures is studied. Both geometric and material nonlinearities are taken into account.Continuum mechanics relations are used to derive general finite element equations. An alternative formulation to Total Lagrangian (TL) and Updated Lagrangian (UL) formulations named Partially updated Lagrangian (PL) formulation i presented.An isotropic small strain co
In September 2020, the EU Commission published the New Pact on Migration and Asylum in order to offer ‘fresh start’ for EU migration law and policy. Complementary pathways for admission to EU territory were among the proposals set out in the Pact. This article takes stock of the different measures suggested by the Commission to create such complementary pathways. It suggests that the aim of creati
A range of third-sector organizations, among them diaconal actors, contributes actively to the welfare mix in the Nordic countries. The independence of these actors is in constant tension with the fact that the organizations are dependent on resources from the surrounding society. Norms and rules influence nonprofit organizations to adopt practices that change the organization, in the direction ofA range of third-sector organizations, among them diaconal actors, contributes actively to thewelfare mix in the Nordic countries. The independence of these actors is in constant tension with thefact that the organizations are dependent on resources from the surrounding society. Norms andrules influence nonprofit organizations to adopt practices that change the organization, in thedirection of an
