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Submerged breakwaters (SBWs) are becoming a popular option for coastal protection, mainly due to their low aesthetic impact on the natural environment. However, SBWs have rarely been employed for coastal protection in the past and therefore, their efficacy remains largely unknown. The main objective of the present study was to investigate the structural and environmental conditions that govern the
This thesis focuses on cognitive impairment in Out-of-Hospital Cardiac Arrest (OHCA) survivors with the main aim to evaluate possible effects by targeted temperature management. Secondary aims are to describe the prevalence of cognitive impairment in a large group of OHCA-survivors, the related symptoms of psychological distress and the actual effect of cognitive impairment for the patient’s abili
This paper presents a novel control architecture for hybrid stiff and compliant control for minimally invasive surgery which satisfies the constraints of zero lateral velocity at the entry point for serial manipulators. For minimally invasive surgery it is required that there is no sideways motion at the point where the robots enter the abdomen. This is necessary to avoid any damage to the patient
Although many studies have investigated the role of customer orientation and learning orientation on a firm's performance in small, medium, and large enterprises, the literature provides little empirical evidence about the role of customer orientation and learning orientation within the hotel industry. This current work investigates the influence of these variables on new service development and t
Soft tissue sarcomas (STS) are challenging as they represent a morphologically and genetically heterogeneous groups of tumors. A multitude of genetic changes, often in the form of fusion genes, were recognized during the 1980's and now constitute a diagnostic lexicon in several STS subtypes, whereas many of the more common subtypes are genetically complex without distinct alterations. Refined STS
The transfer of heat between electrons and phonons plays a key role for thermalmanagement in future nanowire-based devices, but only a few experimental measurements of electron-phonon (e-ph) coupling in nanowires are available. Here, we combine experimental temperature measurements on an InAs/InP heterostructure nanowire system with finite element modeling to extract information on heat flow media
Monoclonal gammopathy of undetermined significance (MGUS) was identified in 3.2% of 21 463 residents of Olmsted County, Minnesota, 50 years of age or older. The risk of progression to multiple myeloma, Waldenstrom's macroglobulinemia, AL amyloidosis or a lymphoproliferative disorder is approximately 1% per year. Low-risk MGUS is characterized by having an M protein < 15 g/l, IgG type and a normal
In this paper, optimization problems arising in model predictive control (MPC) and in distributed MPC aresolved by applying a fast gradient method to the dual of the MPC optimization problem. Although the development of fast gradient methods has improved the convergence rate of gradient-based methods considerably, they are still sensitive to ill-conditioning of the problem data. Since similar opti
The Anselmian claim that God is that than which a greater cannot be thought in virtue of being ‘whatever it is better to be than not to be’ may be accused of incoherence or even unintelligibility. By proposing a non-relative but apparently meaningful analysis thereof, I attempt to defend it against such criticism. In particular, I argue that ‘whatever it is better to be than not to be’ can be plau
Background: We have previously demonstrated that elevated concentrations of tumour-associated trypsin inhibitor (TATI) in both tumour tissue (t-TATI) and in serum (s-TATI) are associated with a poor prognosis in colorectal cancer patients. It was also found that s-TATI concentrations were lower in patients with rectal cancer compared to patients with colon cancer. In this study, we investigated th
Popular Abstract in English A central requirement in the design of bridge, or any structure, is that they are safe and do not fail unexpectedly. To ensure that such occurrences are acceptably rare involves predicting the various ways in which the bridge can fail and ensuring that provisions are made to prevent or control these potential failure. In other words, the risks associated with failure shEngineering design, in concise terms, is what engineers do using what they know. It is the underlying decision making activity that determines what is to be built and how it should be built. An ever present requirement in engineering design is that the structure should be safe. While historical approaches to safety in design relied on experience and engineering judgment, modern approaches have rat
Childhood cancer five-year survival now exceeds 70-80%. Childhood exposure to radiation is a known thyroid carcinogen; however, data are limited for the evaluation of radiation dose-response at high doses, modifiers of the dose-response relationship and joint effects of radiotherapy and chemotherapy. To address these issues, we pooled two cohort and two nested case-control studies of childhood can
Effects of helix destabilization on lipid membrane interaction, liposome rupture, and bacterial killing was investigated for variants of the antimicrobial peptide GKE21 (GKEFKRIVQRIKDFLRNLVPR), an internal sequence of human cathelicidin LL-37, by ellipsometry, circular dichroism, fluorescence spectroscopy, and bacterial radial diffusion assay. GKE21 displayed moderate helix induction in buffer, wh
Background: The n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, which are present in fish, are protective against myocardial infarction. However, fish also contains methylmercury, which influences the risk of myocardial infarction, possibly by generating oxidative stress. Methylmercury is metabolized by conjugation to glutathione, which facilitates elimination. Glut
Forskningsprogrammet Bisek2 skall bidra med kunskap och andra resultat, som ger stöd till en effektiv avvägning av mobiliteten med bil i relation till andra mål och värden. Denna rapporten behandlar en översikt över latent mobilitet och restriktioner för personer med nedsatt funktionell förmåga. Den identifierar behov av fortsatt forskning inom området.
Background and purpose A considerable number of patients who undergo surgery for spinal stenosis have residual symptoms and inferior function and health-related quality of life after surgery. There have been few studies on factors that may predict outcome. We tried to find predictors of outcome in surgery for spinal stenosis using patient- and imaging-related factors. Patients and methods 109 pati
This article introduces the notion of sustainability objects to label objects that come with a claim to promote a more sustainable mode of living. The purpose is to show that organizations that develop such objects contribute to defining sustainability. A case study of the development of a food waste-based biogas and biofertilizers production facility serves as empirical example of sustainability
