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Fabrication and optical characterization of single-mode polymeric embedded waveguides are performed. A specific material combination (SU-8 2005 as core and the modified SU-8 mr-L 6050XP as cladding) is chosen in order to obtain a small refractive index difference for single-mode propagation combined with the conventional fabrication method UV lithography to facilitate the integration of different
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The phenotype of human immunodeficiency virus type 1 (HIV-1) commonly evolves between and within infected individuals, at virus transmission, and during disease progression. This evolution includes altered interactions between the virus and its coreceptors, i.e., chemokine receptors, as well as mannose C-type lectin receptors (CLRs). Transmitted/founder viruses are predominantly restricted to CCR5
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Type 1 diabetes involves the specific destruction of the pancreatic islet β-cells, eventually resulting in a complete dependency of exogenous insulin. The clinical onset of diabetes is preceded by the appearance of autoantibodies against β-cell antigens. The human leukocyte antigen (HLA) region is the single most important genetic determinant of Type 1 diabetes susceptibility, yet variability in t
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Genomic locus at chromosome 9p21 that contains the CDKN2A and CDKN2B tumor suppressor genes is inactivated through mutations, deletions and promoter methylation in multiple human cancers. Additionally, the locus encodes an anti-sense RNA (ANRIL). Both hemizygous and homozygous deletions at the locus targeting multiple genes are fairly common in different cancers. We in this study investigated brea
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Genmäle till Eva af Geijerstam efter hennes kritik mot min recension av Zhang Yimous film Hero.
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Review of Einhorn, L., Vad hände på vägen till Damaskus? På spaning efter den verklige Jesus från Nasaret. Stockholm: Prisma, 2006
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In this article we introduce a new concept, structural identifiability, which plays a central role in identification problems. The concept is useful when answering questions such as: To what extent is it possible to get insight into the internal structure of a system from input-output measurements? What experiments are necessary in order to determine the internal couplings uniquely? The definition
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Background: In the literature radiation of head and neck cancer (HNC) is followed by late side effects for more than a third of the patients. However, nearly all patients seem to experience side effects. The aim was to collect the multitude of these experiences through a patient-developed detailed questionnaire. Methods: 77 of 117 patients responded to a validated questionnaire from the Danish HN
