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Context. Gaia Early Data Release 3 (Gaia EDR3) contains results for 1.812 billion sources in the magnitude range G = 3–21 based on observations collected by the European Space Agency Gaia satellite during the first 34 months of its operational phase.Aims. We describe the input data, the models, and the processing used for the astrometric content of Gaia EDR3, as well as the validation of these res

Context. Hot subdwarfs experienced strong mass loss on the red giant branch (RGB) and are now hot and small He-burning objects. These stars constitute excellent opportunities for addressing the question of the evolution of exoplanetary systems directly after the RGB phase of evolution.Aims. In this project we aim to perform a transit survey in all available light curves of hot subdwarfs from space

While economic geography has contributed deep insights into the knowledge-related determinants of industry emergence, less is known about the legitimacy that people confer to the new industries. Based on a comparative case study in the potable water reuse industry (California, United States) and the video games industry (Hamburg, Germany), this article explores the legitimation dynamics in regiona

The anisotropic properties and pressure sensitivity are intrinsic features of the constitutive response of fiber network materials. Although advanced models have been developed to simulate the complex response of fibrous materials, the lack of comparative studies may lead to a dubiety regarding the selection of a suitable method. In this study, the pressure-sensitive Hoffman yield criterion and th

Acute pancreatitis is a common cause of hospitalization and has an incidence of about 300 per 1,000,000 inhabitants. A majority of patients with acute pancreatitis have mild disease, with an absence of local and systemic complications [1]. The clinical, translational, and experimental research in the field of acute pancreatitis is enormous and various guidelines exist. The guidelines have improved

Industrial packaging can enable efficient and sustainable logistics activities throughout supply chains. Such activities have a great impact on a company's sustainability performance. There has been an increase in research on industrial packaging and its potential to contribute to sustainable supply chains and a circular economy, but the current research is fragmented. The purpose of this study is

Ett praktiskt problem som kan uppstå är att en kärande vill lägga till ett yrkande på väsentligen samma grund som ett tidigare framställt yrkande efter det att ett utslag i mål om betalningsföreläggande eller en tredskodom i tvistemål meddelats mot svaranden och denne begärt återvinning. Då gäller i vissa avseenden reglerna för överrättsprocess, men i andra avseenden ut­gör målet en (fortsatt) tin

Fix some p∈ [0 , 1] and a positive integer n. The discrete Bak–Sneppen model is a Markov chain on the space of zero-one sequences of length n with periodic boundary conditions. At each moment of time a minimum element (typically, zero) is chosen with equal probability, and it is then replaced alongside both its neighbours by independent Bernoulli(p) random variables. Let ν(n)(p) be the probability

Massive bird migration across continents and seas is one of the most spectacular phenomena in nature, involving billions of birds annually. In the autumn, most birds on migration are juveniles migrating for the first time while adults are repeating their migrations. Migration syndrome in individual bird migrants involves multiple behavioural, morphological and physiological adaptations, and migrat

Pulmonary vasodilator therapy is still often an off-label treatment for pulmonary hypertension in children. The aim of this nationwide register-based study was to assess patient characteristics and strategies for pulmonary vasodilator therapy in young Swedish children. Prescription information for all children below seven years of age at treatment initiation, between 2007 and 2017, was retrieved f

Background: Nail psoriasis (NP) is common and of high importance in patients with psoriasis. Complete resolution of NP at week 24‒26 is an unambiguous nail outcome accessible for indirect treatment comparison of biologics. Objective: To evaluate the comparative efficacy of approved biologics in achieving complete resolution of NP at week 24‒26. Methods: A network meta-analysis (NMA) was conducted

Anaplastic thyroid carcinoma (ATC) is a lethal malignancy characterized by poor response to conventional therapies. Whole-genome sequencing (WGS) analyses of this tumor type are limited, and we therefore interrogated eight ATCs using WGS and RNA sequencing. Five out of eight cases (63%) displayed cyclin-dependent kinase inhibitor 2A (CDKN2A) abnormalities, either copy number loss (n = 4) or trunca