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Background: Most in vitro studies of potential osteoarthritis (OA) therapies have used cartilage monocultures, even though synovium is a key player in mediating joint inflammation and, thereby, cartilage degeneration. In the case of interleukin-1 (IL-1) inhibition using its receptor antagonist (IL-1Ra), like chondrocytes, synoviocytes also express IL-1 receptors that influence intra-articular IL-1

The cross section of jets reconstructed from charged particles is measured in the transverse momentum range of 5

Laser cooling is a well-established technique for the creation of ensembles of ultracold neutral atoms or positive ions. This ability has opened many exciting new research fields over the past 40 years. However, no negatively charged ions have been directly laser cooled because a cycling transition is very rare in atomic anions. Efforts of more than a decade currently have La- as the most promisin

BACKGROUND: Monoclonal antibodies (mAbs) towards CGRP or the CGRP receptor show good prophylactic antimigraine efficacy. However, their site of action is still elusive. Due to lack of passage of mAbs across the blood-brain barrier the trigeminal system has been suggested a possible site of action because it lacks blood-brain barrier and hence is available to circulating molecules. The trigeminal g

The treatment of glaucoma is focused on reducing the intraocular pressure to a level at which progression is impeded. A diagnosis of glaucoma is not considered certain until progression is confirmed, and thus detecting progression is a central aspect in both the diagnosing and the monitoring of glaucoma patients. Progression can be identified either through examination of either functional changes

PURPOSE: There is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.METHOD: Semi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky’s theory of sense of coherence. The SRQR checklist was used. RESULTS: Patient’sPurposeThere is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.MethodSemi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky's theory of sense of coherence. The SRQR checklist was used.ResultsPatient's coping

Thrree poems by English poet Rachael Boast in translation to Swedish by Lars Gustaf Andersson

This article develops an analysis of Gender whereby D-gender entersgrammar as a feature variable (edge linker), without a fixed value,either probing n or scanning the context for a value. Only the latterstrategy is available in pronominal gender languages such as English,as they lack n-gender, whereas both strategies are applicable in ngenderlanguages, variably so for variable DPs, depending on th

Mechanical stimuli, such as wind, rain, and touch affect plant development, growth, pest resistance, and ultimately reproductive success. Using water spray to simulate rain, we demonstrate that jasmonic acid (JA) signaling plays a key role in early gene-expression changes, well before it leads to developmental changes in flowering and plant architecture. The JA-activated transcription factors MYC2

This paper discusses topicality in Icelandic grammar as realized in severalphenomena: referential third person pro drop in Old Icelandic, diverse typesof topic drop in Old and Modern Icelandic, and Narrative Inversion (declarativeVS clauses), also in both Old and Modern Icelandic. These phenomena all involveaboutness topics, given topics or both, thus showing that distinct types of topicality are This paper discusses topicality in Icelandic grammar as realized in several phenomena: referential third person pro drop in Old Icelandic, diverse types of topic drop in Old and Modern Icelandic, and Narrative Inversion (declarative VS clauses), also in both Old and Modern Icelandic. These phenomena all involve aboutness topics, given topics or both, thus showing that distinct types of topicality