Filetype
Lytic polysaccharide monooxygenases (LPMOs) are copper enzymes that boost the degradation of different polysaccharides and play important roles in the sustainable production of biofuels, in human and plant pathogens, and potentially also in plastic degradation. Their activity depends on a co-substrate, where recent results show that hydrogen peroxide is the preferred co-substrate. Under typical ex
Aluminium-based SiC particle-reinforced metal matrix composites are widely used in engineering applications due to their exceptional mechanical properties. However, their machining remains challenging due to the mismatch of material properties between the brittle SiC particles and the ductile aluminium matrix, causing tool wear and surface damage. To mitigate these issues, laser inverse problem sc
After diagnosis of craniopharyngioma, patients frequently develop a rapid weight gain leading to morbid hypothalamic obesity due to disease- and/or treatment-associated hypothalamic lesions. Hypothalamic obesity should be diagnosed and treated in the context of hypothalamic syndrome. Hypothalamic syndrome includes neuroendocrine deficiencies, disruption of circadian rhythm, disturbed hunger-satiet
Purpose: The purpose is to describe the Malmö Breast Tomosynthesis Screening Project from the beginning to where we are now, and thoughts for the future. Approach: In two acts, we describe the efforts made by our research group to improve breast cancer screening by introducing digital breast tomosynthesis (DBT), all the way from initial studies to a large prospective population-based screening tri
Background: FLASH radiotherapy using megavoltage (MV) photon beams should enable greater therapeutic efficacy, target deep seated tumors, and provide insights into mechanisms within FLASH. Purpose: In this study, we aim to show how to facilitate ultra-high dose rates (FLASH) with MV photons over a field size of 12–15 mm, using a 6 MeV (nominal) preclinical electron linear accelerator (linac). Our
Given the complex nature of agri-food value chains and related sustainability challenges, the question arises who has the agency and responsibility to address these challenges and facilitate systemic change. We address this question through a mixed method approach and examine experiences with agriculture among different actors along the agricultural value chains in Germany. Based on this, we explo
Natural autoantibodies (NAAbs) are immunoglobulins generated in the absence of antigen provocation, with no inherent pathogenic effect, but instead involved in maintaining immune homeostasis. We aimed to evaluate the implication of immunoglobulin G (IgG) antibodies against heat shock protein 90α (HSP90α) in systemic lupus erythematosus (SLE) patients, focusing on how those NAAbs may interfere with
This paper investigates the impact of artificial intelligence (AI) on hiring and employment, using the universe of job postings published by the Swedish Public Employment Service from 2014 to 2022 and full-population administrative data for Sweden. We exploit a detailed measure of AI exposure according to occupational content and find that establishments exposed to AI are more likely to hire AI wo
Operando resonant photoelectron spectroscopy (RPES) combined with modulated chemical excitation revealed the dynamic evolution of Ce3+/Ce4+ redox states at the surface of CeO2 during the CO oxidation reaction. Using alternating CO and O2 pulses as chemically modulated signals, we monitored the surface states in the valence band region, unveiling the evolution of electronic structure during the cat
In the pursuit of more sustainable agriculture, weeds play a dual role by threatening crop production and simultaneously contributing to farmland biodiversity. Management actions such as the use of fertilisers (fertilisation) may change weed abundance and community composition with consequences for both weed–crop competition and biodiversity. Alleviating the balance between yield and biodiversity
Transient absorption spectra and kinetics are used for detailed studies of energy transfer dynamics within the B850 ring of the LH2 antenna of the purple bacterium Rb. sphaeroides. The initial exciton relaxation was found to occur within the first 100 fs and no temperature dependence of this process was observed. Trnsient abcorption spectra of the LH2 antenna complex at 6 K revealed a new spectral
Coherent nuclear oscillations in two intact photosynthetic light-harvesting pigments were observed for the first time using the approx. 40-fs tunable pulses from a mode-locked Ti:Sa laser. Furthermore, steady-state optical spectroscopy and theoretical calculations provide evidence that exciton states are present in the pigments. The possible antenna configurations that would give rise to the obser
In 1825, an unnamed Stellenbosch official paused his tax collection duties to pen a poem in the margins of the opgaafrol. His verses capture the frustrations of colonial administration but the records themselves–annual tax censuses spanning 1685 to 1844–offer a far richer window into the Cape Colony’s social and economic history. First established by the Dutch East India Company and later maintain
Background: Although up to 25% of proximal humeral fractures are isolated greater tuberosity fractures (IGTFs), comprehensive epidemiological data are lacking. Objectives: Describe the epidemiology and time trends of IGTF in Malmö, Sweden, 1944–2020. Methods: We identified IGTF in Malmö residents (≥18 years) by reviewing relevant radiology examinations during 17 sample years from 1944 to 2020. Fra
Lignocellulosic materials (e.g., straw and bran) are gaining interest as feedstocks for the manufacture of higher value products, recognizing xylooligosaccharides (XOS) as interesting prebiotic compounds, and putting enzymes converting xylooligosaccharides into focus. In this work, we are investigating a XOS converting enzyme from the probiotic bacterium Levilactobacillus brevis (formerly Lactobac
INTRODUCTION: This study examined trends in socioeconomic inequalities in obesity among Portuguese women and men using data from National Health Surveys (NHSs).METHODS: We analysed weighted data from adults aged 20-64 years from the 1998/1999 (n = 20,581), 2005/2006 (n = 13,088), 2014 (n = 7284), and 2019 (n = 5959) NHSs. Obesity was defined as body mass index (BMI) ≥30 kg/m 2, based on self-repo
