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In this paper, we have investigated the interactions between α-synuclein fibrils at different pH values and how this relates to hydrogel formation and gel properties. Using a combination of rheology, small-angle X-ray scattering, Raman spectroscopy, and cryo-transmission electron microscopy (cryo-TEM) experiments, we have been able to investigate the relationship between protein net charge, fibril
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The formation of multilamellar vesicles (MLVs) in the lyotropic lamellar phase of the system triethylene glycol mono n-decyl ether (C10E3)/water is investigated under large amplitude oscillatory shear (LAOS) using spatially resolved rheo-NMR spectroscopy and a combination of rheo-small angle light scattering (rheo-SALS) and conventional rheology. Recent advances in rheo-NMR hardware development fa
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The hierarchical assembly of lipids, as modulated by composition and environment, plays a significant role in the function of biological membranes and a myriad of diseases. Elevated concentrations of calcium ions and cardiolipin (CL), an anionic tetra-alkyl lipid found in mitochondria and some bacterial cell membranes, have been implicated in pneumonia recently. However, their impact on the physic
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In Alzheimer’s diseases (AD), tau pathology is strongly associated with cognitive decline. Preclinical evidence suggests that tau spreads across connected neurons in an activity-dependent manner. Supporting this, cross-sectional AD studies show that tau deposition patterns resemble functional brain networks. However, whether higher functional connectivity is associated with higher rates of tau acc
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The magnetic susceptibility of lanthanide-chelating bicelles was selectively enhanced by introducing 3β-amino-5-cholestene (aminocholesterol, Chol-NH2) in the bilayer. Unprecedented magnetic alignment of the bicelles was achieved without altering their size. An aminocholesterol conjugate (Chol-C2OC2-NH2), in combination with different lanthanide ions, offers the possibility of fine-tuning the bice
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The anatase TiO2(101) surface and its interaction with water is an important topic in oxide surface chemistry. Firstly, it benchmarks the properties of the majority facet of TiO2 nanoparticles and, secondly, there is a controversy as to whether the water molecule adsorbs intact or deprotonates. We have addressed the adsorption of water on anatase TiO2(101) by synchrotron radiation photoelectron sp
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Segregation induced by the adsorption of gas phase species can strongly influence the composition of bimetallic surfaces and can therefore play an important role in influencing heterogeneous catalytic reactions. The addition of palladium to cobalt catalysts has been shown to promote Fischer Tropsch catalysis. We investigate the adsorption of CO onto bimetallic CoPd surfaces on Pd{111} using a comb
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En omfattande syntes av hittillsvarande forskning om Uppåkra.
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The majority of all environmental impacts can be linked to our consumption. As real wages increase, so does consumption levels – more holiday trips, more clothing purchases, faster replacement of products for newer versions,etc. This trend poses a threat to the state of our planet. While the Nordic countries are high in the overall rankings of achieving the UN’s Sustainable Development Goals, they
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Results on the production of 4He and He‾4 nuclei in Pb–Pb collisions at sNN=2.76TeV in the rapidity range |y|
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In this work, growth of InN quantum dots (QDs) on GaN nanowires (NWs) by metal-organic vapour phase epitaxy is demonstrated, illustrating the feasibility to combine 0D and 1D structures for nitride semiconductors. Selective area growth was used to generate arrays of c-oriented GaN NWs using Si3N4 as the mask material. In general, InN QDs tend to form at the NW edges between the m-plane side facets
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Surface affinity, orientation and ion pairing are investigated in mixed and single solute systems of aqueous sodium hexanoate and hexylammonium chloride. The surface sensitive X-ray photoelectron spectroscopy technique has been used to acquire the experimental results, while the computational data have been calculated using molecular dynamics simulations. By comparing the single solute solutions w
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The atomic contributions to valence electronic structure for 37 ionic liquids (ILs) are identified using a combination of variable photon energy XPS, resonant Auger electron spectroscopy (RAES) and a subtraction method. The ILs studied include a diverse range of cationic and anionic structural moieties. We introduce a new parameter for ILs, the energy difference between the energies of the cationi
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Assemblies of anisotropic particles commonly appear in studies of active many-body systems. However, in two dimensions, the geometric ramifications of the finite density of such objects are not entirely understood. To fully characterize these effects, we perform an in-depth study of random assemblies generated by a slow compression of frictionless elliptical particles. The obtained configurations
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We report the first systematic investigation of relativistic effects on the UV-vis spectra of two prototype complexes for so-called photo-activated chemotherapy (PACT), trans-trans-trans-[Pt(N3)2(OH)2(NH3)2] and cis-trans-cis-[Pt(N3)2(OH)2(NH3)2]. In PACT, design of new drugs requires in-depth understanding of the photo-activation mechanisms. A first step is usually to rationalize their UV-vis spe
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On a planetary scale, the D/H ratio on Mars is a key diagnostic for understanding the past history of water on the planet; locally, it can help to constrain the sources and sinks of water vapor through the monitoring of condensation and sublimation processes. To obtain simultaneous measurements of H2O and HDO lines, we have used the Echelle Cross Echelle Spectrograph (EXES) instrument aboard the S
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Huvuddelen av all miljöpåverkan kan kopplas till vår konsumtion. I takt med att reallönerna ökar så ökar också konsumtionen – fler semesterresor, fler klädinköp, snabbare utbyte av produkter mot nyare versioner och så vidare. Denna utveckling utgör ett hot mot planetens tillstånd. I arbetetmed FN:s hållbarhetsmål ligger de nordiska länderna högt i den allmänna rankingen, men när det gäller delmål
