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When statistical linkage to a certain chromosomal region has been found, it is of interest to develop methods which quantify the accuracy with which the disease locus can be mapped. In this paper, we investigate the performance of three different types of confidence regions with asymptotically correct coverage probability as the number of pedigrees grows. Our setup is that of a saturated map of ma

The safety and tolerability of a mite allergoϊd subcutaneous allergen immunotherapy (SCIT) product was previously established. The aim of this study was to find the optimally safe and effective allergoϊd dose by evaluating several dosages in patients with house dust mites (HDM)-induced allergic rhinoconjunctivitis (ARC) using a titrated nasal provocation test (TNPT).

BACKGROUND AND AIMS: Mobility devices (MDs) such as walking sticks, rollators and wheelchairs, often play an important role for older people living at home, striving to remain independent in everyday activities. The aim of this study was to explore how the use of MDs changes over time among very old people in five European countries. METHODS: Empirical data from the ENABLE-AGE Survey Study, part o

Aims: The aim of this study was to find variables related to positive attitudes to physical education (PE) and strong sense of coherence (SOC) among adolescents. Methods: The study included three parts: seven physical tests; a questionnaire which included ways of living, attitudes to PE, and subjective health, the 13-question version of SOC; and information on every student's grades. The study gro

Underlag till utredningen för översyn av producentansvaret (M 2000:01) på uppdrag av BIL Sweden

Spectrum balancing (SB) techniques optimize transmission and can significantly improve digital subscriber lines (DSL) services. In the literature, the DSL system optimization is typically formulated as a rate maximization problem. However, there is an increasing interest in minimizing the considerable amount of power consumed by telecommunication networks. Few works in the SB literature have explo

OBJECTIVE: To analyse the outcome of minor amputations (through, or distal to, the ankle joint) in patients with diabetes. METHOD: All diabetic patients in a defined population undergoing one or more minor amputation between 1982 and 2006 were investigated according to a standardised protocol and were followed until final outcome (healing or death). A total of 410 consecutive amputations in 309 p

The aim of this paper is to explore the role of regional innovation systems and clusters in the economic recovery of old industrial regions. We draw a distinction between three types of cluster-based renewal: an innovation-oriented adjustment of mature clusters (incremental change); the emergence of new agglomerations in established industries (diversification); and the rise of knowledge-intensive