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Visst vore det bra om färre kvinnor dör som följd av komplikationer vid förlossning, eller att ett nytt läkemedel mot depression kommer ut på marknaden? Med mer insikt om ett biologiskt läkemedels fysikaliska stabilitet kan detta bli verklighet. I detta mastersarbete har det biologiska läkemedlet carbetocin studerats med avseende på just detta. Vanliga läkemedel som vi är vana vid att ta i tabletCarbetocin is an uncharged cyclic therapeutic peptide with a tendency to aggregate in solution. Aggregation is undesirable since it, for example, can lead to loss of pharmaceutical effects. To gain a better understanding of peptide aggregation, along with a potential to develop better drug formulations, aggregation of carbetocin was studied. In focus were soluble aggregates in contrast to phase-se

Loudspeakers are used in many different applications and play a vital role in various types of entertainment and communication. To optimize the listening experience, there is a need for an adjustment process to compensate for any effects the environment might have on the loudspeaker’s performance. This thesis presents an adaptive method that utilizes an arbitrary amount of loudspeakers and microph

Digital visual effects (VFX) has become increasingly primary to film and TV production. With major media conglomerates historically exercising great influence over the spatial distribution of industry activity, production localisation has been determined by cost-effectiveness and access to local tax incentive programmes. Despite lack of tax incentives, Swedish VFX firms are capturing an increasing

Sustainable development is currently a topic of great interest due to United Nations’ Brundtland report in which a strong case is made for the need to transform societies towards a more sustainable orientation. Despite relatively few studies on the subject, sustainable entrepreneurs are claimed to play a significant role as change agents in sustainable development. For this reason, we chose to mak

Many economists agree that financial development and economic growth have a positive relationship, that financial structures have been critical for many countries to achieve modern economic growth. In the past decades, foreign investment has become more widespread in the entrepreneurial world, and the banking sector has not been an exception. Mexico experimented during the late 1990’s an unprecede

Syftet med denna studie är att undersöka olika faktorers påverkan på budpremiens storlek vid svenska-, norska- och finska publika företagsförvärv. Vidare syftar studien till att urskilja vilka faktorer som har en signifikant korrelation med budpremien för att bidra till en förklaringsmodell, med ambitionen om att minska värdeförstöring i samband med förvärv. Genom en deduktiv arbetsmetod analyseraThe purpose of this study is to examine various factors’ influence on the size of the bidding premium in Swedish, Norwegian and Finnish public acquisitions. Thus, the study aims to identify which factors have a significant correlation with the bid premium in order to contribute with an explanation model. The ambition is to reduce the value destruction that often occurs in connection to acquisition

Hur låter musiken som spelas av atomer? Även om de inte kan sjunga så kan atomer – de små byggstenarna som bygger världen – interagera starkt med laserljus och då skapa kortvariga ljusblixtar som är lika harmoniska som musik. Att förstå hur laserljus och ljusblixtar är relaterade är genom deras interaktioner med atomer. Detta kommer att hjälpa oss att följa aktiviteten som händer så snabbt att denLight-matter interactions can be used to probe both light and matter as they yield information on a system's state. On the ultrafast timescale, it is possible to employ these interactions to probe fast-occurring phenomena. In particular, one of the few tools for ultrafast spectroscopy are coherent attosecond XUV pulses: light pulses in the extreme ultraviolet range (XUV) whose typical duration

This essay examines the concept of authenticity in relation to William Blake in general and specifically in The Marriage of Heaven and Hell (1790). The Romantic period idealised authenticity but focussed studies into Blake’s relationship with authenticity are relatively few. Previous research contextualizing Blake explores themes such as education, politics and religion, but recent research propos

With recent increased media attention on sexual assault against women, many people question why so many women do not report the crimes. One key may reason lies in the phenomenon of victim blaming. This study examined the effects of social dominance orientation (SDO) and perspective-taking on victim blaming after a sexual assault using a between-subjects experimental design. 111 participants respon

The economic potential of East Germany still severely lags behind that of the West. A scarcity of urban agglomerations is associated with this disparity. The origins of this disparity are insufficiently explored with regards to the spatial inequalities of urban growth induced by the two major shocks of central planning and reunification. By creating long-term time series for city growth and popula

This master thesis aims at improving vehicle positioning in high-speed movement scenarios where global navigation satellite system (GNSS) does not work well. The standard 802.11p, as one of the WiFi family members, it can support to share vehicle information between vehicle and vehicle or between vehicle and infrastructure in a high-speed movement environment. Without the help of GNSS, the vehicle

In view of its complex demographic composition and the lingering controversies on recent civil war historiography, Lebanon provides a unique case of education in a post-conflict context. The absence of a common Lebanese national history curriculum puts individual history teachers under significant pressure. In lieu of an engagement with recent national history, avoided because of its controversy,

The city of Chennai evolved around the river, Cooum. The river supports irrigation to agricultural fields in the north and supplies water to the city of Chennai. It also acts as a major flood carrier for the city. Before the 1960s, the river was clean and used for activities such as bathing, boating and fishing. During the colonial rule, the city was initially planned to sustain a much lesser popu

Syftet med denna uppsats var att undersöka att räkna pinnar - ett informellt uttryck med betydelsen att vara ålagd krav att ta emot ett visst antal patienter per vecka; hur detta påverkar och hanteras av psykologer, och hur påverkan och hantering kan förstås och förklaras. Data insamlades genom sex semistrukturerade intervjuer med psykologer i Skåne, där merparten var anställda vid allmänpsykiatri

Originally from chaos theory, “the butterfly effect” as a concept indicates the verisimilitude of how the most insignificant thing can have a significant ripple effect in a certain process. By analogy, courts are not immune to the “butterfly effect”. Due to the rapid proliferation of legal regimes and bodies, courts are confronted with unorthodox situations requiring that they interface one-anothe

Natural disasters are distressing and destructive for all who are exposed to them; however, certain populations are more vulnerable to their devastating effects than others. In the wake of the 2017 Northern California wildfire, scores of undocumented immigrants were significantly affected. Although the conflagration spread indiscriminately, the subsequent impacts were disproportionately felt by th

With regards to Sweden receiving criticism from the UN about not properly treating children according to the UN convention on the rights of the child, this study aims to further explore this criticism on the subject compulsory care of children and its related investigative work. Children are the pillar stones of society which means authority decisions of compulsory care should always be regarded a

There is a continued need for reliable and convenient nonintrusive thermometric techniques for better understanding and effective control of combustion related processes. In this thesis, three spectroscopic thermometric methods were studied to evaluate the hot flue gas temperatures provided by a multi-jet burner. These methods include the two-line atomic fluorescence (TLAF) thermometry, the Na/K t