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During the last decade, building in wood has increased, mainly due to environmental awareness and targets to decrease the carbon footprint originated from the production of building materials. New technologies such as CLT (cross laminated timber) have accelerated the construction of multi-story wooden buildings. The CLT structure has been used both for housing and offices. Due to the extensive siz

Thuvander, L, Femenias, P, Mjörnell, K, Meiling, P, Unveiling the process of sustainable renovation. Published in open access journal Sustainability 2012, 4(6), in May 2012.Renovation processes are complex and there is a risk of underestimating architectural, cultural, and social values in favor of exterior and interior upgrading, energy efficiency and financing. A synthesized, systematic process is needed for making decisions about renovation measures. The aim of this paper is to survey decision-making procedures aimed for sustainable renovation. We inventory existi

This paper revisits the Power Resource Theory (PRT) by testing one of its more influential claims: the relation between the strength of the labor movement and the reduction of industrial conflicts. Using panel data techniques to analyze more than 2,000 strikes in 103 Swedish towns we test whether a shift in the balance of power towards Social Democratic rule was associated with fewer strikes. The

New, effective treatment strategies for glioblastomas (GBMs), the most malignant and invasive brain tumors in adults, are highly needed. In this study, we investigated the potential of integrin α10Β1 as a therapeutic target in GBMs. Expression levels and the role of integrin α10Β1 were studied in patient-derived GBM tissues and cell lines. The effect of an antibody-drug conjugate (ADC), an integri

Först halvledarteknik, sedan nanoteknik. Tillsammans utgör de huvuddelen av det vi definierar som modern teknik. Användandet av halvledare revolutionerade teknologin under mitten av 1900-talet genom möjligheten att kunna kontrollera halvledarmaterial till att vara antingen elektriskt isolerande eller ledande. Inom elektroniken utgör halvledarna den viktigaste beståndsdelen i till exempel datorer, The topic of III-V nanowires is still, after more than two decades, a growing and lively research area. The areas of application are wide and contain such important topics as energy harvesting, cheap and efficient lighting, high efficiency detectors and new types of electronics. III-V materials offer properties superior to the widely used Si. They can have considerably higher carrier mobility whic

Following intense research efforts, modulation of the immune system has finally proved to be a viable approach for treating malignant disease. Recently, chimeric antigen receptor redirected T cells have achieved promising outcomes in patients with B-cell malignancies and they are currently also being investigated in other haematological malignancies, solid tumours and viral infections. Compared wi

This thesis covers four different topics related to the physics analysis in the ATLAS experiment that uses protonproton collisions data provided by the Large Hadron Collider. The first topic is focused on the numerical simulation of the Transition Radiation Tracker which is one of the ATLAS tracking detectors. The implementation of the alternative Argon based gas mixtures used in the drift tubes i

Microbial cells in bioprocesses are usually described with averaged parameters. But in fact, single cells within populations vary greatly in characteristics such as stress resistance, especially in response to carbon source gradients. Our aim was to introduce tools to quantify population heterogeneity in bioprocesses using a combination of reporter strains, flow cytometry, and easily comprehensibl

Although morphology-based phylogenetic analyses and molecular data suggested that the cycloneuralians might have emerged in the Ediacaran Period, the oldest known fossil remains of cycloneuralians were first reported from the Cambrian Fortunian Stage of South China, and to date four genera and species as well as nine indeterminate forms have been described. Here, we report the latest discoveries o

This article develops a method for simultaneous estimation of density functions for a collection of populations of protein backbone angle pairs using a data-driven, shared basis that is constructed by bivariate spline functions defined on a triangulation of the bivariate domain. The circular nature of angular data is taken into account by imposing appropriate smoothness constraints across boundari

Background: Survivors of myocardial infarction (MI) are at high risk of new major adverse cardiovascular events (MACE). Coronary flow reserve (CFR) is a strong and independent predictor of MACE. Understanding the prevalence of impaired CFR in this patient group and identifying risk markers for impaired CFR are important steps in the development of personalized and targeted treatment for high-risk

Aims: We aimed to discover and replicate associations between leisure-time physical activity and cardiovascular candidate plasma protein biomarkers and to examine whether the associations were independent of body fat. Methods: We used cross-sectional data from two population-based cohorts, the EpiHealth (discovery cohort; n = 2239) and the Swedish Mammography Cohort – Clinical (SMCC; replication c

Resistivity data constitute the largest part of the available information to assess the hydrogeological characteristics of the aquifer system near Oruro, in the central part of the Bolivian Altiplano. Two aquifers are part of this system; top unconsolidated sediments storing fresh water in their granular voids, overlying fractured hard rock formations where saline water was detected in connection

SummaryThe human pathogen Streptococcus pyogenes (GAS) causes both superficial infections, such as strep throat, and invasive infections, such as necrotizing fasciitis, and is responsible for about half a million deaths each year. The number of GAS infections have increased since the 1980’s, due to the emergence of a M1T1 strain that has become widely disseminated. Increased expression of Streptol

The sustainable use of groundwater relies on building up three stages: exploration, development and management. The exploration is crucial to understand the capabilities and limitations of aquifer units; e.g. volume of available water and potential yield, distinction of recharge and discharge zones, and the groundwater quality are developed in this stage. In the Altiplano, groundwater is probably

Two controlled experiments were operated to evaluate the impact of pH on the treatment efficiency of azo dyes within artificial textile wastewater using ponds as a polishing step. The objectives were to assess the (1) inflow water quality; (2) the presence of Lemna minor and the algae Oedogonium spp. on the dye removal and the outflow water quality; and (3) suitability of applying artificial texti

Peripheral artery disease (PAD) is caused by atherosclerosis and associated with an increased risk of leg amputation, cardiovascular disease, and death. A healthy diet has been shown to reduce the risk of cardiovascular events, but relationships between diet, fiber intake, and incidence of PAD are virtually unknown. The aim was to investigate the long-term impact of diet on the development of PAD

Background: The transcription factor signal transducer and activator of transcription 3 (STAT3) is implicated in cancer drug resistance, metastasis, and immunosuppression and has been identified as a promising therapeutic target for new anticancer drugs. Myeloid-derived suppressor cells (MDSCs) play a major role in the suppression of antitumor immunity and STAT3 is involved in the accumulation, ge

To investigate the relation between joint involvement in the upper extremities and grip force in patients with early rheumatoid arthritis (RA). An inception cohort of 225 patients with early RA was followed according to a structured protocol. The same rheumatologist assessed all patients for swollen joints and joint tenderness. Grip force was measured (Grippit; AB Detektor, Gothenburg, Sweden) at