Search results

Background: Programmed death-ligand 1 (PD-L1) immunocytochemical (ICC) analysis of cell blocks (CBs) has recently emerged in clinical practice. Unlike standardized immunohistochemistry on formalin-fixed, paraffin-embedded tissues, cytology involves various preparation methods and fixatives. This study investigated how various fixatives influence PD-L1 immunoreactivity in CBs from malignant pleural

We study the effect of childbirth on local and non-local employment dynamics for both men and women using Belgian social security and geo-location data. Applying an event-study design that accounts for treatment effect heterogeneity, we show that 75 percent of the effect of the birth of a first child on the overall gender gap in employment is accounted for by gender disparities in non-local employ

INTRODUCTION: Cytotechnologists have long been central to cervical cancer screening, although their education and job responsibilities differ markedly across countries. The adoption of primary HPV testing has substantially reshaped cytotechnology workforce needs and professional roles. In Sweden, however, no comprehensive overview of these changes exists. This study therefore examined cytotechnolo

AIMS/HYPOTHESIS: MicroRNAs are potential predictors and mediators of metabolic disease. Cystic fibrosis-related diabetes (CFRD) is the most common comorbidity in cystic fibrosis (CF). Here we aimed to investigate serum microRNAs in individuals with CF and differing glucose tolerance status. Specifically, we hypothesised that the circulating microRNA profile varies depending on glucose tolerance st

Importance: Multiple sclerosis is a chronic neurological progressive disease that can lead to different impairments. It may also impact individuals' quality of life and daily living, including occupational performance and occupational balance. However, occupational balance has not been thoroughly described in this population. Objective: This study aimed to assess occupational balance in a sample o

Background: Late effects of polio (LEoP) are defined as new symptoms, for example, muscle weakness, fatigue, and pain, occurring many years after an acute polio infection. These impairments can lead to difficulties performing everyday activities (ie, activity limitations) that can reduce a person's ability to take part in society (ie, perceived participation restrictions). Yet, no study has explor

Successful outcomes of cell-based therapeutic is highly-dependent on quality and quantity of the cells. Epigenetic modifiers are known to modulate cell fates via reprogramming, hence it is plausible to use them in enhancing the plasticity of mesenchymal stem cells. In this study, we aimed to study the effects of 5-Azacytidine (5-AzaCR), an epigenetic modifier, pretreatment on mesenchymal stem cell

This paper studies the time-dependent first-in-first-out (FIFO) queuing model with a single intermittently available server and variable-sized bulk arrivals and bulk departures. The time between arrivals, servicing time, and server availability time follows an exponential distribution. The difference-differential equations are used for developing system equations, and the Laplace transforms (L.T.)

This article examines the subversive mobilities and vernacular legal navigation of Uzbek migrants in Finland and Sweden, highlighting their tactical responses to restrictive Nordic migration regimes. Drawing on ethnographic fieldwork (2022–2025), including interviews, focus groups and digital ethnography, we explore how migrants with precarious statuses navigate legal ambiguity, administrative opa

PURPOSE: To estimate the effect of dexamethasone eye drops on the risk of progression from type 2 retinopathy of prematurity (ROP) to ROP requiring traditional treatments.DESIGN: Register-based cohort study.PARTICIPANTS: Preterm infants born before 30 weeks' gestation from 2015-2018 (control years) and from 2020-2021 (intervention years) registered in the Swedish Quality Register for ROP at 4 Swed

People often draw inferences from sequences of past performance, sometimes perceiving patterns even in random outcomes. This has fueled debates regarding phenomena such as the hot hand and gambler’s fallacies. With the growing use of artificial intelligence (AI) systems for forecasting and decision support, it becomes important to understand how people form beliefs from sequences of outcomes attri

We present a genome assembly from an individual female Podarcis liolepis (Catalonian Wall Lizard; Chordata; Lepidosauria; Squamata; Lacertidae). The assembly contains two haplotypes with total lengths of 1 574.00 megabases and 1 478.08 megabases. Most of haplotype 1 (97.05%) is scaffolded into 20 chromosomal pseudomolecules, including the W and Z sex chromosomes. Haplotype 2 was assembled to scaff

The chemical industry, essential to economic growth and innovation, faces critical environmental sustainability challenges, notably pollution, emissions, and intensive resource use. Motivated by the need for practical tools to address these issues, this research develops a structured, comprehensive framework to assess and enhance environmental sustainability within the chemical sector. The framewo

Direct, time-resolved measurements of the amino radical (NH2) are critical for understanding plasma-assisted ammonia (NH3) combustion, in terms of both plasma-accelerated NH3 decomposition and reduced NOx emission, yet such data remain scarce. The current study focuses on the spatiotemporal characteristics of NH2 using laser-induced fluorescence (LIF) in a quasi-one-dimensional NH3/air flame subje

With the rapid growth of Internet media, content tagging has become an important topic with many multimedia understanding applications, including efficient organisation and search. Nevertheless, existing visual tagging approaches are susceptible to inherent privacy risks in which private information may be exposed unintentionally. The use of anonymisation and privacy-protection methods is desirabl

This chapter examines the myth of neophilia – the belief that new products are inherently better than repaired ones – and how it has shaped consumer culture, business models and policy. Rooted in postwar consumerism, neophilia has been reinforced by marketing, technological change and growth strategies that promote novelty as progress while casting repair as outdated or uneconomical. The emphasis

Malnutrition-Related Diabetes Mellitus (MRDM) is a subtype of diabetes associated with chronic malnutrition, primarily observed in low- and middle-income countries (LMICs) and impoverished populations. The disease is characterized by onset in young, lean patients with a history of chronic undernutrition, insulin deficiency, persistent insulin sensitivity, and resistance to ketosis. MRDM was recogn

The increasing complexities and vulnerabilities in globalised supply chains, exacerbated by recent crises such as pandemics, climate change, and geopolitical disruptions, have underscored the urgent need for sustainable and resilient supply chain management. The growing interdependence of global trade networks makes them more susceptible to disruptions, highlighting the importance of digital trans

Despite shrinking civic space, civil society organisations (CSOs) in Uganda continue to shape pathways toward sustainable and inclusive agricultural transformation. This paper explores why and how CSOs use non-confrontational strategies, particularly advocacy to influence policy and institutional processes regarding agricultural development. It draws on in-depth interviews with CSO actors, includi