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Breastfeeding during Pregnancy and its Association with Childhood Malnutrition and Pregnancy Loss in Low- and Middle-Income Countries

Breastfeeding confers a wide range of benefits to mothers and children, and in many contextsmay continue for several years after the birth of a child. As a result, breastfeeding duringpregnancy (BDP) is a common occurrence throughout low- and middle-income countries.Nevertheless, yet there has been little research into its association with the health of breastfedchildren or the outcomes of the pre

Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk

The high prevalence (>5%) of autoimmune hypothyroidism (AIHT) provides a unique opportunity to dissect genetic contributions to systemic and organ-specific autoimmunity. Here we performed a genome-wide association meta-analysis of 81,718 AIHT cases in FinnGen and the UK Biobank, identifying 418 independent signals (P < 5 × 10−8). At 48 of these loci, a protein-coding variant is, or is highly corre

Family history of stroke and cardiovascular diseases in early-onset cryptogenic ischaemic stroke

BACKGROUND: Familial aggregation of stroke is well-documented, yet few studies have examined associations between stroke subtypes-particularly early-onset cryptogenic ischaemic stroke (eCIS)-and broader family history (FH) of cardiovascular disease. Such associations may provide insights into underlying etiologic mechanisms. METHODS: In this multicentre case-control study, we included eCIS patient

Projection-based discrete-time consensus on the unit sphere

We address discrete-time consensus on the Euclidean unit sphere. For this purpose we consider a distributed algorithm comprising the iterative projection of a conical combination of neighboring states. Neighborhoods are represented by a strongly connected directed graph, and the conical combinations are represented by a (non-negative) weight matrix with a zero structure corresponding to the graph.

Addressing Gaps in Butterfly Population Monitoring to Catalyze Global Insect Conservation

The conservation community sorely lacks a global indicator of change in insect populations. Given widespread insect declines, addressing this gap is key for conservation and policy targets. We suggest that butterfly monitoring programs can serve as the foundation for an effective global network of insect monitoring. To assess this potential, we bring together an international consortium and calcul

Grassland age and local adaptation shape drought resilience across semi-natural grassland populations

Increasing frequency and intensity of droughts threaten grassland ecosystems. Semi-natural grasslands vary in age from ancient to younger sites established on former arable land. While species richness and composition are known to affect drought resilience, little is known about how grassland age shapes drought responses through eco-evolutionary processes at the plant population level. We explored

Ecology and evolution of pyrazines in insects

Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen-containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and mammals. In this review, we focus on the role of pyrazine

Self-Assembly and Gelation Behavior of Methacrylated PEO–PPO–PEO Triblock Copolymer Pluronic F127

Methacrylated Pluronic triblock copolymers are widely used as photo-cross-linkable hydrogels, yet the effect of terminal methacrylation on self-assembly and thermoreversible gelation prior to cross-linking remains poorly understood. Here, we systematically investigate how the degree of methacrylation influences micellization, micelle packing, and gelation in Pluronic F127 using differential scanni

Assessment of air kerma–area product in computed tomography using small solid-state dosemeters

Technological advances in computed tomography (CT) have highlighted limitations of traditional dose descriptors such as computed tomography dose indexvol and dose-length product, particularly for wide-beam and modulated acquisitions. This study investigates a CT-specific, operational air kerma–area product derived from time-resolved measurements using small solid-state dosemeters mounted at the ga

Moonlight drives the energy balance and annual cycle of a nocturnal forager

Behavioral, physiological, and life-history adaptations to the lunar cycle are global phenomena across trophic levels and ecosystems yet remain poorly understood because of the challenges of studying free-living organisms at night. We show that the lunar cycle regulates both daily foraging activity and foraging success in the red-necked nightjar-a nocturnal avian insectivore-and that moonless peri

The impossibility of social inclusion : The ethno-racist welfare discourse in Sweden Welfare Racism: The Discursive Dimension

The fall of 2022, with the election success of a coalition of right wing and ethnoracist parties, marks the transition from a racialized to a racist state in Sweden. We analyse the discourses of three welfare projects in Swedish racial capitalism - Keynesian, Neoliberal, and ethnoracist - in relation to safety/security.Methodologically, we use CDA analysing elite institutional texts (party documen

Population-level analysis of glycoprotein glycoforms

The structure and function of many proteins are regulated post-translationally through glycan attachment. These glycans, assembled via competing enzymatic reactions, generate diverse glycoform populations - variants sharing a protein backbone but differing in glycan structures. While current analyses often focus on individual glycoforms, we demonstrate that population-level glycoform analysis - in

Review of Transforming Chinese Patriarchy : Chinese Families in the Twenty-first Century

Transforming Chinese Patriarchy, edited by Gonçalo D. Santos and Stevan Harrell, is athought-provoking collection of meditations upon changes in the gendered landscape ofcontemporary Chinese society. The book focuses on“gender systems”primarily as anelement of“family systems”, and it deals with“patriarchal configurations”as seen througha lens that is both gendered and inter-generational. It contai

Effectiveness of a structured physical therapist-led intervention compared to usual care in people with longstanding hip and groin pain referred to orthopaedic care in Sweden : protocol for a randomised controlled trial (the HIPSTER trial)

INTRODUCTION: People with longstanding hip and groin pain (LHGP) are often referred to orthopaedic care. Physical therapist-led interventions are recommended in consensus statements as the first line of treatment, but it is unknown if structured interventions are more effective than usual care. The aim of this trial is to evaluate the effectiveness of a structured physical therapist-led treatment

Identification of antibiotic induced persister cells in Streptococcus agalactiae

Antibiotic persistence is a phenomenon, where a small fraction of a bacterial population expresses a phenotypic variation that allows them to survive antibiotic treatment, which is lethal to the rest of the population. These cells are called persisters cells, and their occurrence has been associated with recurrent disease. Streptococcus agalactiae is a human pathobiont, able to cause invasive infe