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Freeze-drying is the preferred method to manufacture proteins in their solid state thus the understanding of the relationship between cycle parameters and cake properties remains of great interest. The present study aims to investigate the influence of the freezing conditions in the material properties at different layers throughout the dried structure, in the presence and absence of a protein. Pl

Using data from the Swedish municipality of Botkyrka, this paper quantifies the trade-off between non-wastefulness and truthfulness in sequential admission systems for public and private schools. The results show that minimizing seat waste while preserving truthfulness is possible by restricting first-round applications to either private or public schools, depending on which type of school that is

Background: Multimorbidity, i.e. two or more non-communicable diseases (NCDs), has been associated with venous thromboembolism (VTE), but whether multimorbidity is a predictor for incident VTE is unknown. Aims: To examine the associations between multimorbidity and its severity with risk of incident VTE, and examine the association between nine different disease clusters and incident VTE. Methods:

In recent years, studies of surfaces at more realistic conditions has advanced significantly, leading to an increased understanding of surface dynamics under reaction conditions. The development has mainly been due to the development of new experimental techniques or new experimental approaches. Techniques such as High Pressure Scanning Tunneling/Force Microscopy, Ambient Pressure x-ray Photo emis

Background Large, international cohort studies generate high-level evidence, but are resource intense. In end-of-life care such studies are scarce. Hence, planning for future studies in terms of data on screening, recruitment, retention and survival remains a challenge. Objectives The aim was to describe recruitment, follow-up and survival in a multinational study of patients’ and relatives’ expec

The circular economy (CE) transformative model depends on policy design and implementation in multiple socio-economic contexts. Temporal priorities based on security concerns can stimulate risk-averse circular policies that compromise achieving Sustainable Development Goal 12 for responsible consumption and production. However, the CE literature lacks empirical evidence on how these concerns affec

Background: Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking. Objectives: This study sought to evaluate the 5-year clinical outcomes of IFR- vs FFR-guided PCI in a real-world setting. Methods: We assessed the 5-year outcomes of all patients undergoing IFR or FFR assessment be

Gravitational interactions were studied by measuring the influence of small external field masses on a microwave resonator. It consisted of two spherical mirrors, which acted as independent pendulums individually suspended by strings. Two identical field masses were moved along the axis of the resonator symmetrically and periodically between a near and a far position. Their gravitational interacti

Articial intelligence (AI) is widely discussed across policy sectors, including global environmental politics. At the 28th United Nations Climate Change Conference in 2023 (COP28), national governments decided to explore AI’s role in climate solutions and its associated challenges and risks through the #AI4ClimateAction Initiative. In March 2024, the UN General Assembly adopted a resolution to “se

Objectives: In axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) patients initiating secukinumab, we aimed to assess retention rates and proportions of patients achieving remission and low disease activity (LDA), according to disease activity measures and patient-reported outcomes at 24 and 48 months. Patients and methods: Data on patients with axSpA and PsA who initiated secukinumab t

In recent decades, ethicists have engaged with new developments in human reproductive technologies from a variety of angles. Yet there has been relatively little effort to problematize the concept of reproduction itself. In this paper, we examine the question of what reproduction is and its relationship with biology. We show that reproduction is commonly assumed to entail biological parenthood—an

Purpose: Use of mechanical imaging (MI) as complementary to digital mammography (DM), or in simultaneous digital breast tomosynthesis (DBT) and MI - DBTMI, has demonstrated the potential to increase the specificity of breast cancer screening and reduce unnecessary biopsies compared with DM. The aim of this study is to investigate the increase in the radiation dose due to the presence of an MI sens

Steadily increasing use of computer-generated models sets high demands on the realistic representation of breast tissue and abnormalities. Previously, we demonstrated the use of Perlin noise to simulate breast lesions. Now, we expand the previous model by simulating heterogeneous lesion composition. We demonstrate a new approach to simulating 3D soft tissue lesions, with additional benefits of Per

This thesis develops an ethical framework called the ethics of authenticity and puts it to work through concrete engagement with seven contemporary Scandinavian films. It starts by tracing the contradictory developments of modern freedom, highlighting the tensions of freedom and solidarity and how this comes to the fore in ethics, politics and film aesthetics. Inspired by Simone de Beauvoir’s exis

2,5-Furandicarboxylic acid (FDCA) is a promising building block for biobased recyclable polymers and a platform for other potential biobased chemicals. The common route of its production is by oxidation of sugar-derived 5-hydroxymethylfurfural (HMF). Several reports on biocatalytic oxidation using whole microbial cells or enzymes have been reported, which offers potentially a greener alternative c

Recent research in evolutionary economic geography addressing radical innovation and grand challenges has advocated for a shift in focus from single technologies and products toward interrelated configurations of technologies and institutions. This suggests moving beyond explaining innovation and industrial dynamics primarily by the existence of appropriate knowledge and capability stocks, to incl

Public relations professionals’ use of generative artificial intelligence (GenAI) tripled during 2023. Despite this surge, there is a notable lack of in-field studies examining GenAI and other CommTech implementation in public relations. To address this research gap, we adopt the view of the digital transformation of public relations as a socio-technical change process and explore how a communicat

Demonstrating how strategic communication management creates value has long been considered a key challenge for communication departments and managers. Theorizing and explaining how strategic communication creates value and how this value can be demonstrated has, therefore, emerged as a central research concern in public relations and strategic communication. While extant literature acknowledges t