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Introduction: People living with acromegaly and neuroendocrine tumours (NETs) may be treated with injectable somatostatin receptor ligands (SRLs), administered by either a caregiver or as self-injection via a proprietary or generic device. Injection device attributes that contribute to ease of use and storage, minimise preparation requirements, and reduce injection pain are associated with improve

If the Anthropocene marks a changed way of being in the world resulting from the integration of human activity and geological processes, a main question is how this situation may be aesthetically represented and with what implications. This article sketches an aesthetics of the Anthropocene by analyzing artistic engagements with advanced tools of visual calculation used in the context of the envir

Why are Nordic sociologists not providing diagnoses of society these days? What has happened to our desire to describe the wider sociocultural currents of the world we live in? Where indeed are the present-day Danish Sennett, the Finnish Rosa, or the Swedish Bauman? These questions resurface now and again, yet without gaining substantial traction. Even so, present-day Nordic sociology is in many w

BackgroundThe global distribution of HIV-1 subtypes is evolving, which is reflected in the Swedish HIV cohort. The subtype HIV-1A6, which may be prone to developing resistance to cabotegravir, is the most common subtype in Ukraine.AimWe aimed to examine trends in HIV-1 subtype distribution in Sweden, with a special focus on HIV-1A6, and to describe the virology, demography and treatment of Ukraini

OBJECTIVE: Charcot foot (CF) requires prolonged offloading of the affected foot to decrease the risk of deformity. The earliest phase in active CF (stage 0) is characterized by inflammatory signs without established fractures or skeletal deformity. We investigated whether offloading in stage 0 influences duration of total contact casting (TCC), risk of recurrence, and future need for surgery.RESEA

Background: Tumour deposits are suggested to impact prognosis in colon cancer negatively. This study assessed the impact of tumour deposits on oncological outcomes.Methods: Data from the Swedish Colorectal Cancer Registry for patients who underwent R0 abdominal surgery for TNM stage I-III colon cancer between 2011 and 2014 with 5-year follow-up were analysed with multivariable analysis. Patients w

This article analyzes the appropriate types of water rights systems for different regions with varying water resource conditions in China. The most appropriate water rights systems for various zones were determined by comparing the value of influencing factors with corresponding thresholds in China’s second-class zones of water resources. It is shown that a riparian rights system under water withd

How different were the lives of elites and commoners in early complex societies? This paper examines this question using data from three fisher-hunter-gatherer sites in southern California. Using shell bead counts from burials as proxies for social status and previously published human stable isotope values as indicators of dietary practices, we examine the relationship between diet and status acr

Inteins are self-splicing protein elements found in viruses and all three domains of life. How the DNA encoding these selfish elements spreads within and between genomes is poorly understood, particularly in eukaryotes where inteins are scarce. Here, we show that the nuclear genomes of three strains of Anaeramoeba encode between 45 and 103 inteins, in stark contrast to four found in the most inte

INTRODUCTION: Many depressed patients do not achieve remission with available treatments. Anhedonia is a common residual symptom associated with treatment resistance as well as low function and quality of life. There are currently no specific and effective treatments for anhedonia. Some trials have shown that dopamine agonist pramipexole is efficacious for treating depression, but more data is nee

The study objective in this article was to present the state-of-the-art on teachers’ professional development to enhance educational quality for students with autism spectrum disorders (ASD) in primary and secondary education. A systematic review was conducted, following the PRISMA guidelines. Quantitative, qualitative, and mixed-methods studies were eligible for inclusion. Fifteen studies were id

This study examined whether teachers’ professional development of their relational competence with students with attention deficit hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD) modifies teachers’ and students’ perceptions of their teacher-student relationships (TSR). Participants comprised teachers (n = 33) and students (n = 232) from two elementary schools: one intervention

Kraven på försvagad konflikt­rätt hotar Sveriges välfungerande lönebildning och riskerar att öka arbetslivs­kriminaliteten. I förlängningen väntar ingrepp från politiker och från EU.

Bayesian phylogenetics is now facing a critical point. Over the last 20 years, Bayesian methods have reshaped phylogenetic inference and gained widespread popularity due to their high accuracy, the ability to quantify the uncer‑ tainty of inferences and the possibility of accommodating multiple aspects of evolutionary processes in the models that are used. Unfortunately, Bayesian methods are compu

Exhaled SARS-CoV-2-containing aerosols contributed significantly to the rapid and vast spread of covid-19. However, quantitative experimental data on the infectivity of such aerosols is missing. Here, we quantified emission rates of infectious viruses in exhaled aerosol from individuals within their first days after symptom onset from covid-19. Six aerosol samples from three individuals were cultu

Sedan 1920-talet har det funnits planer på att använda contortatall i svenskt skogsbruk men först kring 1970omsattes de till storskaliga planteringar i norra Sverige.Sedan 1970-talet har contortatallen debatterats och knutits till olika sammanhang och skilda värderingsregimer.Återkommande har forskare samt företrädare för skogsnäringen och olika miljörörelser försökt att avgränsacontortans betydel

In this paper, Safety Control Barrier Functions (SCBFs) were used to adjust the null-space compliant behavior of a redundant robot to improve safety in Human–Robot Collaboration (HRC) without modifying the robot behavior with respect to its main Cartesian task. A Lyapunov function was included in an energy storage formulation compatible with strict passivity to provide global asymptotic stability