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Potential of using Machine learning Technology to predict site location of Burial Sites in the Åland Islands.

Den senaste utvecklingen inom underfältet Digital Arkeologi är införandet av Artificiell Intelligens (AI) i kombination med Maskininlärning (ML) som ett verktyg för att förutsäga potentiella arkeologiska platser i ett landskap. Vidare möjliggör utvecklingen av en LiDAR (Ljusdetektering och avstånd) teknologi med en upplösning på 5 laserpunkter/m2 på Åland (samt i stora delar av Finland) att analys

Modulations of glypican-1 heparan sulfate structure by inhibition of endogenous polyamine synthesis. Mapping of spermine-binding sites and heparanase, heparin lyase, and nitric oxide/nitrite cleavage sites

Cell surface heparan sulfate proteoglycans facilitate uptake of growth-promoting polyamines (Belting, M., Persson, S., and Fransson, L.-A. (1999) Biochem. J. 338, 317-323; Belting, M., Borsig, L., Fuster, M. M., Brown, J. R., Persson, L., Fransson, L.-A., and Esko, J. D. (2001) Proc. Natl. Acad. Sci. U. S. A., in press). Here, we have analyzed the effect of polyamine deprivation on the structure a

Winter site use by Afro-Palearctic migrants in Ghana : site persistence and densities of Willow Warbler, Pied Flycatcher, Melodious Warbler and Common Redstart

Little is known about the variation within and among species of long-distance migrants in behavioural strategies and habitat choice on their non-breeding grounds. We report results from regular ringing operations carried out during the winter seasons 2009–2013 and transect counts in 2013, 2015 and 2016 in the Sudan Savanna Zone in Ghana. The best supported capture–mark–recapture model included spe

Specific Derivatization of the Active Site Tyrosine in dUTPase Perturbs Ligand Binding to the Active Site

Selective modification of one (of three) tyrosine residue per enzyme monomer leads to inactivation of dUTPase of the retrovirus equine infectious anemia virus (EIAV). The substrate dUMP and the cofactor Mg2+protects against inactivation and modification, in agreement with the study onE. colidUTPase (Vertessyet al.(1994)Biochim. Biophys. Acta1205, 146-150). Amino acid analyses of nitrated dUTPases

Multiscale Modeling of the Active Site of [Fe] Hydrogenase: The H-2 Binding Site in Open and Closed Protein Conformations

A series of QM/MM optimizations of the full protein of [Fe] hydrogenase were performed. The FeGP cofactor has been optimized in the water-bound resting state (1), with a side-on bound dihydrogen (2), or as a hydride intermediate (3). For inclusion of H4MPT in the closed structure, advanced multiscale modeling appears to be necessary, especially to obtain reliable distances between CH-H4MPT+ and th

Survival in cancer of unknown primary site: population-based analysis by site and histology

Cancer of unknown primary (CUP) is diagnosed at a metastatic stage, conferring an unfavorable prognosis. The natural history of the disease is poorly understood, which complicates diagnosis, treatment and follow-up. Population-based survival data are lacking regarding location and histology of metastases. From the Swedish Cancer Registry, 18 911 CUP patients were identified between years 1987 and

Geological characterisation of geophysical lineaments as part of the expanded site descriptive model around the planned repository site for high-level nuclear waste, Forsmark, Sweden

Svenska Kärnbränslehanteringen (SKB) startade ett projekt under 2020 i närheten av Forsmark i Sverige med målet att utöka deformationszonsmodellen till att inkludera hela dräneringsområdet runt om det planerade slutförvaret för använt kärnbränsle. Detta arbete bygger på en lineamentmodell som var skapad för SKB. Denna modell använder sig av magnetiska data tillsammans med höjddata samt data insamlThe Swedish Nuclear Fuel and Waste Management Co. (SKB) started a project in 2020 near Forsmark, Sweden with the aim to expand the deformation zone model to encompass the entire catchment area around the planned repository for spent nuclear fuel. This thesis builds upon a lineament model that was constructed for SKB which utilizes airborne magnetic data supported by airborne Very Low Frequency (VL

Mapping of the factor Xa-binding site on factor Va by site-directed mutagenesis.

Activated coagulation factor V functions as a cofactor to factor Xa in the conversion of prothrombin to thrombin. Based on introduction of extra carbohydrate side chains in recombinant factor V, we recently proposed several regions in factor Va to be important for factor Xa binding. To further define which residues are important for factor Xa binding, we prepared fifteen recombinant factor V varia

Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding

The role of K396 in the enzymatic catalysis and the antigenicity of the 65 kDa isoform of glutamate decarboxylase (GAD65) was analyzed using the K396R GAD65 mutant. GAD65 is a major autoantigen in Type 1 diabetes and autoantibodies directed to GAD65 are widely used markers for this disease. We found that (1) recombinant human GAD65 is fully enzymatically active; (2) the K396R mutation abolished GA

A model for the temperature and density dependent reemergence of the bark beetle Ips typographus

A model is presented that describes the reemergence of parent spruce bark beetles, Ips typographus, based on breeding density and temperature conditions. Laboratory data obtained at one constant temperature provide the distribution of reemergence time and different combinations of threshold temperatures and degreedays (°D) at mean reemergence. Of these combinations, 167.71 °D above 7.5 °C gave the

Land Use and Land Cover Change in Tunisia

CMES Deputy Director Ronny Berndtsson has co-authored an article on land use and land cover change in Tunisia. The article is published in the journal Remote Sensing. CMES Deputy Director Ronny Berndtsson has co-authored the article "Analysis of Four Decades of Land Use and Land Cover Change in Semiarid Tunisia Using Google Earth Engine" together with Nesrine Kadri (National Agronomic Institute of

https://www.cmes.lu.se/article/land-use-and-land-cover-change-tunisia - 2025-11-23

Three scenarios for globalisation. A view from cultural semiotics

Three scenarios for globalisation. A view from cultural semiotics Göran Sonesson Using the concept of the auto-model, this text describes global society as a device people use to understand their relation to other cultures. Three scenarios are analysed in terms of a model each : first, we consider the hypertrophy of the Internal Other, which results from the displacements of sizeable populations