Search results

Popular Abstract in Swedish Att få en övergripande förståelse för hur mänskliga celler påverkas av metallbaserade läkemedel är viktigt, eftersom de har visat sig vara väldigt effektiva för behandling av exempelvis testikel- och äggstockscancer. För att utforska bakomliggande orsaker har forskningsprojektets utgångspunkt varit att studera kliniskt välkarakteriserade metallbaserade läkemedel som exeGaining a detailed understanding of how human cells are affected by metal-based drugs is crucial, since these drugs have shown great potential in cancer treatment. Cisplatin is used to treat many different types of cancer, e.g. testicular, ovarian, melanoma, bladder, non-small cell lung cancer, small cell lung cancer, myelomas and lymphomas. The miRNA expression profiles in different human cancers

Popular Abstract in Swedish Arbetet i denna avhandling syftar till att förbättra etanolproduktionen från lignocellulosa. Etanol framställd från förnyelsebara råvaror har fått förnyad uppmärksamhet på grund av den växande medvetenheten om den globala uppvärmningen och farhågor för en trytande tillgång på olja. Lignocellulosa utgör en potentiell råmaterialkälla för framtida storskalig etanolproduktiThe work presented in this thesis has been aiming at improving ethanol production from lignocellulose. Ethanol from renewable resources is receiving renewed attention due to apprehensions of global warming and dwindling oil reserves. Lignocellulose constitutes a potential raw material source for large scale ethanol production. To produce ethanol from lignocellulose, the hemicellulose and cellulose

Dynamics of optically excited electronic states have been studied in solid films and solutions of semiconducting polymers and model compounds. Transient absorption, monitored in the spectral range from 0.9 eV to 2.5 eV with a time resolution of about 100 fs, was the main experimental technique. Transient anisotropy, obtained from different polarizations of light, was employed to trace the dipole m

The commercial feasibility of ethanol production from biomass is dependent on the availability of lignocellulose in large amounts at low cost. Various kinds of agricultural residues are of interest, due to the fact that these feedstocks have well-established cultivation procedures already in place, as well as technology for harvest and transportation. In the current work, the utilization of sugarc

Why is there hunger in sub-Saharan Africa? What forces drive the global food system? What is the global food system? To approach these questions, this study investigates power and politics in food, in its production and in its organization. Proceeding from a critical realist approach, focus of this study is on the challenge of African smallholder food insecurity and how it is presented as part of

The accurate diagnosis of malaria is crucial for ensuring an effective treatment and combating the developing drug resistance of the parasite. The standard diagnostic method, consisting of light microscopy in combination with Giemsa-staining, requires manual examination through a trained clinician. This is time-consuming and prone to human error. While emerging diagnostic innovations can overcome

Understanding the dynamic of a population via either abundance or density is crucial for wildlife conservation. The brown bear (Ursus arctos) is a commonly distributed, yet elusive species, playing a major role in the ecosystem. Usually monitored with genetic sampling, hunted bags, or telemetry data, the use of camera traps for bear monitoring is still to this day a rarely used, yet promising meth

As climate change and unsustainable waste practices present major global challenges, effective waste management in developing countries becomes critically important. In South Africa, organic waste constitutes a significant share of general waste and is often landfilled, contributing to methane emissions and serious health risks for the population. In response, the Western Cape province has introdu

Head and neck squamous cell carcinoma (HNSCC) is a heterogenous cancer with poor prognosis, especially for patients with advanced or recurrent disease. The complex tumor microenvironment (TME) plays an important role in mediating immune evasion and therapy resistance. To improve preclinical testing, advanced 3D in vitro and ex vivo models such as spheroids, organoids, and tumor slice cultures have

Background and objective: We established prognostic nomograms incorporating prostate-specific membrane antigen (PSMA) positron emission tomography (PET) parameters standardised by Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE; PPP1). Here, we develop an updated PPP2 risk score from a large international multicentre registry study. Methods: We included 6128 prostate cancer pati

Solpaneler på taket är numera en vanlig syn, men vart tar elen vägen när solen skiner som mest? I detta examensarbete har det undersökts hur flerbostadshus kan använda egna batterier för att spara pengar, bli mer självförsörjande och samtidigt stötta elsystemet. Svaret är att batterier kan löna sig, om de används smart. När elnätet blir allt mer pressat och produktionen från förnybar energi varierThis thesis examines the economic potential of lithium-ion battery storage systems in multi-family residential buildings in Sweden, focusing on profitability, revenue opportunities, and the factors influencing investment decisions. The increasing share of renewable electricity, combined with the electrification of society, has intensified the need for energy storage solutions capable of balancing

Importance: The ability to predict sudden cardiac death (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM) is currently inadequate. Late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) imaging is associated with SCD events in adults with HCM. Objective: To examine the prognostic significance of LGE in patients with HCM who are younger than 21 years. De

Augustenborg storm water system has become well known for its incorporation of urban green spaces. Open storm water system was developed in late 1990s by disconnecting impervious surfaces from combined sewers as a result of flooding problem in the basements after heavy rain events. The open storm water management system consists of open channels and ponds, a small wetland, green infiltration areas

“1000 Extra” is a project that takes off in the sub optimal conditions that city planning in the 20-th century has left behind for the future. First and foremost looking at the conditions of residential areas planned based on doctrines stemming in modernism, the project proposes desnsifying the not-so-dense areas in Lund, consisting of row houses and other residential buildings in the same categor

Micropollutants in our sources of freshwater is an issue which requires immediate attention. The presence of pharmaceuticals, endocrine disrupting agents, pesticides and other harmful compounds have proven to have impact on the aquatic as well as on human life. Treated wastewater being a major source of ingress of micropollutants into the aquatic environment, the current standards do not stipulate

This thesis investigates how urban experimentation is governed in the new development district in Sege park in Malmö. Together with with private developers and a local NGO the municipality test and experiment with solutions for how the sharing economy can contribute to reduce the future resident’s climate impact and living costs. By using the theoretical lens of governmentality this thesis focusse

The release of anthropogenic greenhouse gases (GHGs) has substantially increased the global mean surface air temperature. Increases in global mean surface air temperature will lead to warmer and drier conditions, promoting more frequent, long-lasting, intense forest wildfires. The usage of remote sensing (RS) can aid in quantifying forest characteristics and large-scale changes in forest ecosystem

Segregation är ett vanligt fenomen som uppstår över hela världen. De negativa konsekvenserna av boendesegregation har visat sig vara många för de som bor i mindre välbärgade stadsdelar. Bland konsekvenserna finns bland annat hälsorelaterade motgångar, men även sämre förutsättningar under skolgången och i det framtida arbetslivet har konstaterats. Sydafrika lämpar sig väl för att studera segregatioSegregation is a common phenomenon arising worldwide. Residential segregation has been shown to have several negative consequences for people living in less wealthy neighbourhoods, such as health-related setbacks and being less likely to cope with school. South Africa is an especially well-suited country to study segregation and methods to counteract it to achieve better integration and more harmo

I denna rapport undersöks hur olika åtgärder påverkar trafiksituationen för oskyddade trafikanter i korsningar. Undersökningen görs främst utifrån de tre aspekterna trafiksäkerhet, framkomlighet och omgivande miljö. Arbetet omfattar sex korsningar i Helsingborg som har byggts om vid olika tidpunkter och där olika åtgärder har vidtagits. För att göra en bedömning av åtgärdernas påverkan på trafiksäThis report examines how different traffic improvement measures affect the traffic situation for vulnerable road users at intersections. The survey is conducted mainly based on the three categories of road safety, accessibility and the surroundings. The work investigates six intersections in Helsingborg that have been rebuilt at different times and where different measures have been taken. To eval

This work aimed to characterize single chain fragment variables (scFvs) against S100A7 and Calprotectin, proteins part of the Ca2+ binding S100 family that have been associated with inflammatory diseases and cancer. The mechanisms governing the physiological functions of S100 proteins are not fully understood, but it is known that many of them contribute to maintaining homeostasis in the intracell