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INTRODUCTION.: The most common immunosuppressive treatment in de novo renal transplantation is a triple regimen that includes tacrolimus, mycophenolate mofetil (MMF) and corticosteroids, and that may also include antibody induction. Whether nephrotoxicity is an issue with tacrolimus at the currently used dosages remains an open question. METHODS.: We pooled data from three large, randomized, de no

Objective: An association between small for gestational age (SGA) and risk for celiac disease (CD) in childhood has previously been reported. However, this association may reflect residual confounding by genetic or environmental factors. For example, presence of subclinical CD in the mother might be a common cause of both SGA and CD in the offspring. We investigate whether SGA is causally associat

The outcome of management of diabetic foot ulcers remains a challenge and there remains continuing uncertainty concerning optimal approaches to management. It is for these reasons that in 2008 and 2012 the International Working Group of the Diabetic Foot (IWGDF) working group on wound healing published systematic reviews of the evidence to inform protocols for routine care and to highlight areas w

OBJECTIVES: To explore the associations between frailty and reproductive axis hormones (as an important regulatory system) in middle aged and older men. DESIGN: Cross-sectional. SETTING: The European Male Aging Study. PARTICIPANTS: Three thousand two hundred nineteen community-dwelling European men aged 40 to 79. MEASUREMENTS: Interviewer-assisted questionnaires to assess physical activity, health

BACKGROUND: Overdose (OD) is a common cause of death in opioid users. Also, many current opioid users report a history of non-fatal OD. The present study aimed to identify factors associated with a history of non-fatal OD. METHODS: A sample of 7085 Swedish criminal justice clients with alcohol or drug misuse was assessed, using the Addiction Severity Index. Subjects reporting use of opioids during

Granulosa and theca cell tumors of the ovary account for 2-3% of ovarian malignancies. This study includes 54 patients with the diagnosis of granulosa cell tumors of the ovary treated between 1953 and 1987. Median age at diagnosis was 57 (27-83) years. The lesions were staged according to FIGO. The number of patients in various stages was IA, 41; IB, 3; IC, 3; IIB, 6; and III, 1. Median tumor size

A 59-year-old female secretary was referred for evaluation and treatment of a non-healing painful ulcer on the medial aspect of her right lower leg. The ulcer had been recurrent almost every year for the past 9 years, often healing during the winter season. She had since early childhood been overweight (currently 87 kg, 170 cm, body mass index 30) and had difficulty in using compression stocking.

Topiramate is biochemically classified as a fructopyranose sulphamate. Discovered as early as 1979, during middle 1980's it was approved in many countries for the treatment of epilepsies and migraine prevention. More recently, in the experimental stage, possible new indications have been disclosed: treatment of obesity, bipolar disorder, also cessation of smoking, neuropathic pain, cerebral pseudo

OBJECTIVE: To explore factors related to hand pain in persons with radiographic hand osteoarthritis (OA).METHODS: Persons in the Musculoskeletal Pain in Ullensaker Study with radiographic hand OA (≥1 joint with Kellgren/Lawrence grade ≥2) were included (n = 530). We examined the cross-sectional association between possible explanatory variables and hand pain in the entire sample and in 2 hand OA p

This scientific report has mainly studied the concept of Industry 4.0 and the possibility to send data from a temperature sensor to the cloud, a process which is an example of the term Internet of Things. The study has been conducted for the consultant business Rejlers to give the CEO as well as the Technical Manager a broader view of how they could implement IoT on behalf of costumers in the futu

UPPSATSENS TITEL: Den Femte Positioneringsfällan SEMINARIEDATUM: 2013-05-28 ÄMNE/KURS: Magisteruppsats i företagsekonomi 30 högskolepoäng (ECTS), FEKN90 FÖRFATTARE: Stina Cedergren och Malin Svensson HANDLEDARE: Jens Hultman Fem nyckelord: varumärkespositionering, varumärkesidentitet, förändringsprocessen, positioneringsfällor, yngre och kvinnlig målgrupp SYFTE: Syftet med uppsatsen är att TITLE: The Fifth Position Trap SEMINAR DATE: 2013-05-28 COURSE: Master thesis in business administration, 30 credits (ECTS), FEKN90 AUTHORS: Stina Cedergren and Malin Svensson ADVISOR: Jens Hultman KEYWORDS: Brand positioning, brand identity, process of change, positioning traps, a younger and female target group. PURPOSE: The purpose of this thesis is to analyze and describe the challenges

Åklagarens objektivitetsplikt har under de senaste åren blivit särskilt uppmärksammad med anledning av Thomas Quick-fallet. Under 90-talet erkände Quick ett 30-tal mord, varav han blev dömd för åtta av dem. Emellertid förändrades allt år 2008 när Quick tog tillbaka sina erkännanden. Detta ledde till ett antal omprövningar, där han så småningom blev friad från samtliga åtal. I såväl domstolar som mIn recent years, the prosecutor's duty to act objectively has received special attention due to the case of Thomas Quick. During the 90’s, Quick confessed to over 30 murders, of which he was convicted for eight of them. However, all this changed in the year of 2008 when he took back his confessions. This led to a number of re-trials, where Quick eventually was cleared from all charges. Extensi

Popular science summary: Transcriptional regulation of HIF-2α in neuroblastoma Neuroblastoma is the most common solid tumor in childhood. The presence of hypoxia -regions of low levels of oxygen- causes a more immature tumor phenotype that is related to a more aggressive form of this cancer. Hypoxia is mainly directed by Hypoxia Inducible Factors (HIF)-1α and HIF-2α. High levels of HIF-2α expre

Binära föreningar beståendes av sällsynta jordartsmetallerna och rutenium uppvisar intressanta egenskaper såsom superledande förmåga och intressanta magnetiska egenskaper. För att förstå varför vissa föreningar uppvisar sådana egenskaper är det essentiellt att studera föreningarnas kristallstruktur. I denna rapport undersöks föreningar, i 35-38 at. % Ru regionen, beståendes av praseodym, neodymiumBinary alloys comprising of the rare earth metals along with ruthenium, RE-Ru, have been noted to display superconductivity at low temperatures. Furthermore the alloys display interesting magnetic properties such as anomalies in magnetization measurements below the magnetic ordering temperature. In order to understand how some compounds obtain these intrinsic properties it is vital to investigate

The average woman uses 11,000 tampons during her lifetime. Both sanitary pads and tampons have been proven to contain low levels of dioxins, which are a group of highly toxic environmental pollutants known to cause cancer, reproductive damage and endocrine disruption. Some scientists have concluded that dioxin levels in tampons are insignificant to the overall dioxin exposure of menstruating women

Background: Despite their vulnerability to the toxic effects of certain metals, biomonitoring data on adolescents are limited. In the present study, we assessed blood concentrations of toxic metals (cadmium [Cd], total mercury [Hg], and lead [Pb] in a national representative sample of Swedish adolescents. We also examined the associations of Cd, total Hg and Pb with habitual intakes of major energ

Relatively little is known about the relationship between socio-demographic factors and the chemical exposome in adolescent populations. This knowledge gap hampers global efforts to meet certain UN sustainability goals. The present work addresses this problem in Swedish adolescents by discerning patterns within the chemical exposome and identify demographic groups susceptible to heightened exposur

We investigated the relationship between lipid binding glycoprotein apolipoprotein E (apoE; gene APOE) polymorphisms (ε4 allele carriers versus no carriers = ε4+/ε4−) and trace elements (TEs) (e.g., (methyl)mercury, arsenic, lead, cadmium, selenium, manganese, copper, and zinc) in mothers (N = 223) and their new-borns (N = 213) exposed to potentially toxic metal(loid)s from seafood consumption. Th

I denna bok utforskas den rättsliga hanteringen av duellbrott som ärekränkningar och dueller med dödlig utgång under stormaktsväldets slutskede. Med inspiration från New Cultural History och teorier om manlighet och våld analyseras lagtexter, rättsfall, prästers och rättslärdas skrifter samt anklagade duellanters brev och nådeansökningar. Studien fokuserar på hur den rättsliga diskursen kring duelThis dissertation examines duelling crimes in Sweden during the first half of the 18th century. During this period such crimes could involve verbal insults concerning honour as well as duelling, resulting in death. Inspired by the methods and perspectives of New Cultural History and by theories of masculinity the study argues that masculine violence is a cultural category that is historically deve

Purpose: This study explores how people account for their translation, negotiation and shaping of environmentally relevant practices as information practices in their everyday life during the holidays and asks further how these narratives can be seen as accounting for situated information practices. It focuses on how summer guests holidaying in southern Sweden talk about how they connect different