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Neural Network Approaches To Survival Analysis

Predicting the probable survival for a patient can be very challenging for many diseases. In many forms of cancer, the choice of treatment can be directly impacted by the estimated risk for the patient. This thesis explores different methods to predict the patient's survival chances using artificial neural networks (ANN). ANN is a machine learning technique inspired by how neurons in the brain fu

Diffuse large B-cell lymphoma - tumour characteristics on RNA and protein level associated with prognosis

Diffuse large B-cell lymphoma (DLBCL) is the most frequent lymphoma subtype. In Sweden 450 new cases are diagnosed annually. With modern anthracycline-containing chemotherapy DLBCL is potentially curable, with an estimated overall cure rate of approximately 50% for patients with advanced stage disease. Through molecular profiling of DLBCL the ?cell-of-origin concept? has been established: patients

Towards Gene Therapy of Osteopetrosis.

Popular Abstract in Swedish Osteopetros är ett samlingsnamn för en grupp av sjukdomar som påverkar benombildningen i vår kropp. Denna term kan lätt förväxlas med den betydligt vanligare sjukdomen osteoporos (benskörhet). Trots ordens snarlikhet skiljer sig dessa sjukdomar sig avsevärt från varandra. Osteo är latin för ben och medan poros kan översättas med porös betyder petros sten. Även om de oliThe goal in this thesis is development of gene therapy for malignant infantile osteopetrosis (IMO), a rare but severe genetic bone disease. The concept of osteopetrosis implies dysfunction or lack of osteoclasts, the bone resorbing cells in our body, resulting in failure of normal bone breakdown. Although involved in bone remodeling, osteoclasts are of hematopoietic origin and may potentially be t

Half-sandwich complexes with amino-quinoline ligands - synthesis, antiplasmodial and antimycobacterial activities

Popular Abstract in Swedish Malaria och tuberkulos är två av de mest dödliga infektionssjukdomarna i världen. Biologiskt är de två infektionerna mycket olika; malaria orsakas av en encellig parasit, en plasmodium, som sprids mellan personer med hjälp av myggbett, och tuberkulos av en bakterie som sprids via upphostade bakterier. Vidare drabbar malaria vanligtvis blodomloppet medan tuberkulos oftasMalaria and tuberculosis are two of the most deadly infectious diseases that exist. Both diseases predominantly affect the most vunerable parts of society. Additionally the treatment of both diseases are complicated by growing and spreading resistance against the drugs used to treat them. Chloroquine was once described as a wonder drug for its combination of efficacy, low price and tolerable side

Kontinuitetsprincipen - En princip som lägger krokben för barnets bästa?

Föräldrabalkens 6 kap. 2 a § stadgar att barnets bästa skall vara avgörande för alla beslut i frågor om vårdnad, boende och umgänge. Barnets bästa är en princip som går att finna i såväl internationella dokument som i nationell lagstiftning. Begreppet barnets bästas innebörd är ej uttryckligen definierad i varken de internationella dokumenten, såsom barnkonventionen, eller i svensk nationell lagstAccording to the Swedish parental code 6 chapter 2 a §, the best interest of the child shall be conclusive for all decisions in matters of custody, residency and right to access. The best interest of the child is a principle which can be found in both international documents and in national legislation. The concept of the principle of the best interest of the child is not expressly defined in neit

Högsta Domstolens revolution av narkotikapraxis - En studie om straffvärdebedömningen i narkotikamål

This essay concerns the assessment of penal value in cases regarding narcotic offenses. It particularly concerns the level of guilt as shown by the court for the criminal act and associated factors. In the early 1960's the punishment for narcotic offences were fines or inprisonment for up to two years in accordance with narcoticregulation. With the adoption of the narcotic penal law the maxim

Development of an assay for quantifying A1M rescue of heme treated human kidney cells

Hem och A1M – ett test på liv och död Hem är en av kroppens viktigaste hjälpar-molekyler. När hem är bundet till proteiner hjälper det cellerna att utvinna energi och rensa ut gifter. Det mesta hemet finns i de röda blodkropparna där hem används till att transportera syre i kroppen. Tyvärr är obundet hem giftigt. Det har visat sig att havandeskapsförgiftning, ett tillstånd som kan drabba gravida,

Flattening filter free volumetric modulated arc therapy for extreme hypofractionation of prostate cancer - Decreasing the treatment time and reducing the impact of prostate motion

I skrivande stund är sju olika cancercentra i Sverige, däribland Skånes Universitetssjukhus i Lund, mitt uppe i en gemensam randomiserad studie som undersöker behandling av prostatacancer med två olika strålningsscheman. Patienterna i studien blir slumpvis tilldelade antingen en standardbehandling, där de får en liten mängd strålning vid 39 olika tillfällen, eller en så kallad hypofraktionerad behPurpose: This work examined the feasibility of flattening filter free (FFF) volumetric modulated arc therapy (VMAT) for extreme hypofractionation of prostate cancer. The aim was to investigate the potential gain in treatment time per fraction for extreme hypofractionation of prostate cancer, while preserving or improving the treatment plan quality and radiation delivery quality. The impact of intr

Investigation of the native starch-ethyl cellulose film coating for colon targeting

The aim of this study was to optimize a function starch-ethyl cellulose film for targeting the therapeutically active substance to the colon in the disease state for patients suffering from inflammatory bowel diseases. This study includes: • The preparation of the polymeric films and the investigation of the characterization (for example mechanical properties, water uptake, dry mass loss, and mic

FGF signaling in specification of hESC-derived definitive endoderm

Popular Abstract in Swedish Diabetes är en snabbt växande folksjukdom som redan har drabbat 200 miljoner världen runt. Det finns två typer av sjukdomen: typ I samt typ II diabetes. Den förstnämnda drabbar vanligtvis de unga och beror på en s.k. autoimmun reaktion där kroppens egna immunförsvar av okänd anledning plötsligt inte känner igen insulincellerna och börjar attackera dem. Typ II diabetes uDiabetes affects around 200 million people worldwide. Curing diabetes would require the prevention of autoimmune destruction of beta cells and restoration of the beta cell mass restored either through regeneration or transplantation of the insulin producing cells. Islet transplantation according to the Edmonton protocol have been the most promising therapeutic option for Diabetes type I patients,

Research

Research | Construction Sciences Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiable in

https://www.byggvetenskaper.lth.se/english/research/ - 2026-05-25

Publications

Publications | Division of Innovation Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiab

https://www.innovation.lth.se/publications/ - 2026-05-25

Staff

Staff | Division of Innovation Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiable info

https://www.innovation.lth.se/staff/ - 2026-05-25

Lund University Export Control Programme Compliance Programme For Dual Use Items

Microsoft Word - Lunds universitets exportkontrollprogram_STYR2020_2073_English_tillg Page 1 of 23 Vice-Chancellor DECISION Reg. No. STYR 2020/2073 Date 2021-10-21 Lund University’s export control programme – compliance programme for dual-use items Approved by the vice-chancellor on 21 October 2021. Postal address Box 117 Visiting address Sandgatan 5 Telephone +46 222 69 29, +46 46 222 00 00 E-mai

https://www.staff.lu.se/sites/staff.lu.se/files/2021-12/Lund%20University%20export%20control%20programme%20compliance%20programme%20for%20dual%20use%20items.pdf - 2026-05-27

Ny uppdragsbeskrivning arbetsgrupp for infrastruktur 20210315

Postadress Box 117 Besöksadress Scheeletorget 1, 221 00 Lund Telefon 046-222 45 77, 046-222 00 00 E-post tina.trollas@fs.lu.se Webbadress www.lu.se Forskningsnämnden Uppdragsbeskrivning för den universitetsgemensamma forskningsnämndens arbetsgrupp för forskningsinfrastruktur Bakgrund Forskningen vid Lunds universitet behöver stödjas av ändamålsenlig och tillgänglig infrastruktur. Processerna röran

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2021-03/ny_uppdragsbeskrivning_arbetsgrupp_for_infrastruktur_20210315.pdf - 2026-05-27

The conference Anti-racism and Diversity in Academia

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. The conference was organized within the project “Collaborative toolbox towards ant-racism and academia" On the 28th of May we organized a full-day conference ANTI-RACIST STRATEGIES IN TEACHING, LEARNING, RESEARCH AND INSTITUTIONAL LIFE as a cooperation between scholars gathered in the local group of Antirasistisk Ak

https://www.genus.lu.se/artikel/conference-anti-racism-and-diversity-academia - 2026-05-27

Utlånad till Migrationsverket i två veckor

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Fakultetskoordinatorn Helen Wiman har hållit en ström av flyktingar i handen de senaste två veckorna. Istället för att jobba på universitet har hon registrerat flyktingar för Migrationsverket. Spännande, givande – men också utmattande. Fakultetskoordinatorn Helen Wiman har under två veckor lånats ut till Migrationsv

https://www.lu.se/artikel/utlanad-till-migrationsverket-i-tva-veckor - 2026-05-27

Drones offer new insights into boreal peatland CO2 emissions

Boreal peatlands store large amounts of carbon, but warmer and drier conditions caused by climate change may turn these ecosystems into carbon sources. Equipped with drones and thermal cameras Julia Kelly, who recently received her doctorate at the Centre for Environmental and Climate Science (CEC), has studied what factors affect the CO2 fluxes in peatland ecosystems. Boreal forests and peatlands

https://www.merge.lu.se/article/drones-offer-new-insights-boreal-peatland-co2-emissions - 2026-05-27

Snow insulation effects across the Arctic : evaluating a revised snow module in LPJ-GUESS

The effect of future changes in temperature and precipitation patterns on arctic ecosystem functioning is often assessed using state-of-the-art ecosystem models. Many models however lack detailed representation of wintertime processes, as pointed out by recent studies (Wang et al. 2016, Slater and Lawrence 2013). This bias may influence the derived outputs, such as soil temperature, permafrost ext

Development of alginate and gelatin-based pleural and tracheal sealants

Pleural and tracheal injuries remain significant problems, and an easy to use, effective pleural or tracheal sealant would be a significant advance. The major challenges are requirements for adherence, high strength and elasticity, dynamic durability, appropriate biodegradability, and lack of cell or systemic toxicity. We designed and evaluated two sealant materials comprised respectively of algin