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Disease burden and unmet need for acute allergic reactions – A patient perspective

BACKGROUND: Acute allergic reactions (AARs) occur shortly after exposure to an allergen, and the severity is on a continuum. Systemic corticosteroids (CS) are mainstay treatment of moderate to severe AARs, whereas those at risk of the most severe AARs (ie, anaphylaxis) are also recommended prescription of epinephrine autoinjectors. There is limited research on the impact of AARs not fulfilling the

Large eddy simulations of turbulent premixed bluff body flames operated with ethanol, n-heptane, and jet fuels

Large Eddy Simulations (LES) are carried out targeting an unconfined premixed bluff body burner operated with ethanol, n-heptane, Jet A, and a Sustainable Aviation Fuel (SAF) labeled C1. The purpose is to validate the chosen simulation methodology for these fuels, which have not been simulated in the targeted case before, and to provide new information about how they burn and stabilize. The combus

The Cambrian–Ordovician transition in dysoxic facies in Baltica— diverse faunas and carbon isotope anomalies

The Cambrian–Ordovician boundary interval in Scandinavia is characterized by largely endemic trilobite species and fossil-meager intervals within the Alum Shale Formation. Previous investigations of this interval in Scandinavia, based on drill cores, are rather sketchy. In order to characterize the faunal signature in a largely dysoxic setting during this time interval, as well as providing biostr

Mechanical Load Identification for Spontaneous Tool Failure Monitoring

The problem of spontaneous cutting tool failure, such as tool chipping and breakage, is becoming more and more important in the manufacturing technology. The sponataneous tool failure is usually associated with the stresses subjected on the tool during a metal cutting process. When the maximum stress acting in a cutting tool exceeds its critical stress, which is usually determined by tool geometry

Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis.

Background: Genetic polymorphisms associated with common aetiologically complex diseases have recently been identified through genome-wide association studies. Direct-to-consumer genetic testing for such polymorphisms, with provision of absolute genetic risk estimates, is marketed by several commercial companies. Polymorphisms associated with atrial fibrillation (AF) have shown relatively large r

Hur man särskilt beaktar unga lagöverträdare i straffrättsprocessen

Det straffrättsliga systemet präglas idag av en nyklassisk kriminalpolitik vilken betonar handlingen, handlingens konsekvenser, skulden och brottets svårhet. Dessa faktorer bestämmer straffvärdet vilket medför att de straffrättsliga principerna om bl.a. proportionalitet, förutsebarhet och konsekvens upprätthålls. Straffvärdet som sådant utgör nämligen grunden för påföljdsvalet. Men det finns ytterThe criminal justice system currently emphasizes the action, the consequences of the action, the liability and the gravity of the offense. These factors determine the penalty value, which means that the criminal justice principles such as proportionality, predictability and consistency is maintained. The penalty value as such constitutes the basis when deciding on a suitable penalty. But there are

Användning av hälsodata för forskningsändamål - En undersökning av kraven i dataskyddsförordningen och etikprövningslagen

Hälsodata har stor betydelse för forskning om sjukdomar och behandlingsmetoder. Ett sätt att genomföra forskningen är att samla in hälsodata direkt för det specifika forskningsändamålet. Ett annat sätt är att återanvända hälsodata som redan har samlats in för andra ändamål för det aktuella forskningsändamålet. De två centrala regelverken som reglerar när och hur hälsodata får användas inom forskni

Tolkning av georadarprofiler över grundvattenmagasinet Verveln - Gullringen i Kalmar län

I Sverige utgörs majoriteten av våra grundvattenresurser av isälvavlagringar i form av rullstensåsar och isälvsdeltan bestående av sand och grus. Isälvsavlagringarna är utan tvekan de mest betydelsefulla grundvattenförekomsterna för Sveriges dricksvattenförsörjning. Mer än 80% av landets alla vattenverk utnyttjar vatten från dessa resurser. En ojämn fördelning av grundvattenresurserna i kombinatioMost of Sweden’s groundwater resources are made up from glacifluvial deposits such as eskers and deltas that consist of sand and gravel. Glacifluvial deposits are certainly the most significant groundwater resources for drinking water supplies in Sweden. Groundwater resources are used to supply more than 80% of all the existing water plants nationwide. These important resources have an uneven dist

Novel strategy to synthesize homonuclear cubic heteroleptic metal-organic cages using Ruthenium(II) complexes and N-donor ligands : Synthesis, Characterization, Complexation, and Attempts

Supramolekylär kemi är ett ämne där formationen av molekylära sammansättningar och deras interaktioner undersöks, innebärande en kombination av både organisk kemi och oorganisk kemi. Ämnet omfattar bindningen av metallkomplex med organiska ligander där hela metalkomplexet kan ses som en atom medan liganderna är själva bindningarna, vilket resulterar i supramolekylära komplex av olika form och storMetal-Organic Frameworks (MOF) are a group of polymeric porous self-assembly structures consisting of a combination of coordinated metal ions and organic-linker molecules resulting in supramolecules with one-, two- or three-dimensional structures. The porosity of the macromolecule allows smaller molecules to enter and remain coordinated via intermolecular interactions, therefore the potential use

Bordering Homelessness: Investigating Children’s Housing First as a selective policy in a neoliberal housing regime

This thesis investigates the model Children’s Housing First as a selective policy in the neoliberal housing context in Sweden. The two research questions are (1) how is Children’s Housing First operating as a selective housing policy? and (2) to what extent does Children’s Housing First reinforce or challenge neoliberal components in the current Swedish housing regime? Children’s Housing First is

Forskningen möter fältet : en kartläggning av branschtidskrifternas forskningsbevakning 1994-2002

Library and information science (LIS), is a research area marked by theoretical diversity and strong influence from both the developing library profession, as well as other social sciences. During the development of LIS several attempts have been made to define its scientific identity. The definition of what constitutes core, boundaries and the superior identity of LIS is still debated among resea

Exposure assessment for the prevention of musculoskeletal disorders

Popular Abstract in Swedish Exponeringsskattning för att hindra uppkomst av belastningsskador Skador på muskler som uppkommer av olämpliga arbetsrörelser och arbetsställningar (belastningsskador) utgör ett stort problem i alla industrialiserade länder. Definitionen av vad som innefattas i begreppet arbetsskada varierar mellan olika länder, varför det är svårt att göra jämförelser. Kostnader för arWork-related musculoskeletal disorders of shoulder/neck are a major and increasing problem. Beside the pain, they involve high cost for the employer and society. The total expenditure for the musculoskeletal disorders of the neck and upper limb have been estimated to 0.5-2.0% of the Gross National Product (GNP) in the Nordic countries. Due to the lack of precise knowledge of exposure/response rela

Spectral light absorption by ambient aerosols influenced by biomass burning in the Amazon Basin. I : Comparison and field calibration of absorption measurement techniques

Spectral aerosol light absorption is an important parameter for the assessment of the radiation budget of the atmosphere. Although on-line measurement techniques for aerosol light absorption, such as the Aethalometer and the Particle Soot Absorption Photometer (PSAP), have been available for two decades, they are limited in accuracy and spectral resolution because of the need to deposit the aeroso

Correlation of in Vivo [18F]Flortaucipir with Postmortem Alzheimer Disease Tau Pathology

Importance: In Alzheimer disease (AD), tau filaments form neuronal inclusions in neurites (neuropil threads) and in somata (neurofibrillary tangles), and neurite tau pathology constitutes the most common pathology. Positron emission tomography (PET) ligands have been developed to detect in vivo tau pathology in AD. However, the association of AD tau pathology post mortem with in vivo tau PET reten