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Contact Allergy to Acrylates

Popular Abstract in Swedish Akrylatallergi Plastmaterial består av stora molekyler som kallas polymerer samt tillsatsämnen som tillsätts för att modifiera materialets egenskaper. Polymerer bildas när det sker en stegvis reaktion mellan monomerer så att större molekyler bildas. Allergiframkallande ämnen i plastsystem kan vara monomererna, härdarna, modifierarna eller andra tillsatsämnen. Akrylater

Endothelial Induced EMT in Breast Epithelial Cells with Stem Cell Properties

Epithelial to mesenchymal transition (EMT) is a critical event in cancer progression and is closely linked to the breast epithelial cancer stem cell phenotype. Given the close interaction between the vascular endothelium and cancer cells, especially at the invasive front, we asked whether endothelial cells might play a role in EMT. Using a 3D culture model we demonstrate that endothelial cells are

Mitral Valve Surgery: Effects on Cardiac Reverse Remodeling, Hemodynamics, and Clinical Outcome

Popular Abstract in Swedish Mitralisklaffen (lat. valva mitralis; valva bicuspidalis) är den klaff i hjärtat som finns mellan vänster förmak och vänster kammare. Till utseendet liknar klaffen påvens huvudbonad, mitra, varifrån namnet härstämmar. Mitralisklaffen består av två segelliknande flikar (klaffblad) med en upphängningsapparat som fäster sig i vänster-kammarens vägg. När vänster kammare konNormalization of life expectancy after mitral valve surgery is highly dependent on early diagnosis and referral for surgical treatment. Among cases treated surgically, the majority (60–70%) have a degenerative etiology, which is also easiest to repair. The general aim of this thesis was to bring research on treatment of degenerative mitral regurgitation a step further in order to improve clinical

Tissue repair in lung disorders

The remodeling phase of tissue repair in lung disorders such as idiopathic pulmonary disease, asthma, obliterative bronchiolitis, and after lung transplantation is not well understood. One of the key players in fibrosis is the fibroblast and its progenitor, the fibrocyte. The fibroblast is the main producer of extracellular matrix molecules such as collagen, versican, perlecan, biglycan, and decor

"Är det så här vi är" : Om utbildning som normalitet och om produktionen av studenter

This thesis addresses what students describe as their reasons for attending university, their descriptions of their encounters with the university milieu, and what significance they believe the existence of a local university such as Halmstad in south-west Sweden may have had in this. The empirical basis of the study consists of interviews with 58 students taking one of three courses at Halmstad U

“No Friends but the Mountains” Understanding Population Mobility and Land Dynamics in Iraqi Kurdistan

Popular Abstract in Swedish För att få en uppfattning om hur framtida miljöförändringar kommer att påverkar vårt samhälle är det viktigt att studera eventuella samband mellan migration, samhälle och miljö. Klimatförändringar väntas inom en snar framtid leda till stora befolkningsförflyttningar till följd av exempelvis ökad stormfrekvens, torka, havsnivåhöjning och vattenbrist. Migration kan å andr

Translational perspectives on MSMB and CRISP3 expression and regulation in prostate cancer

Popular Abstract in Swedish Prostatacancer är en mycket vanlig form av cancer, och det har visats att cirka hälften av alla män över 70 år har tumör i prostata. Prostatacancer är ofta en latent form av cancer, vilket innebär att den sällan ger kliniska symtom förrän i ett framskridet stadium. Sedan PSA testet började användas på 90-talet har antalet diagnostiserade fall av prostatacancer blivit alProstate cancer is currently the most common form of cancer in Sweden. Currently, the only biomarker used in the clinic is serum PSA, and there is a great need for new biomarkers that may increase the diagnostic and prognostic information so that better predictions can be made, and treatment may be tailored. Here, we have investigated two proposed biomarkers microseminoprotein-β (MSMB) and cystein

An extensive polymerase chain reaction-allele-specific polymorphism strategy for clinical ABO blood group genotyping that avoids potential errors caused by null, subgroup, and hybrid alleles

Background: ABO genotyping is complicated by the remarkable diversity at the ABO locus. Recombination or gene conversion between common alleles may lead to hybrids resulting in unexpected ABO phenotypes. Furthermore, numerous mutations associated with weak subgroups and nondeletional null alleles should be considered. All known ABO genotyping methods, however, risk incorrect phenotype predictions

Cystatin C, beta-2-microglobulin and beta-trace protein in pre-eclampsia

Background. An altered renal function is an essential component of the patho-physiology of pre-eclampsia. The plasma levels of low molecular mass proteins, e. g. beta-trace protein, beta-2-microglobulin and cystatin C, are increased in the third trimester of normal pregnancy. The plasma levels of cystatin C and beta-2-microglobulin are further increased in preeclampsia, and the cystatin C level ha