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Evidence for De Novo Expression of Thymic Insulin by Peripheral Bone Marrow-derived Cells.

Thymic expression of insulin has been suggested to play a major role in negative selection of autoreactive T cells and tolerance induction against pancreatic beta cells. Furthermore, the expression of insulin in peripheral antigen-presenting cells (APC) has been clearly demonstrated but whether thymic negative selection and tolerance induction also depends on peripheral influx of self-antigens (Ag

På väg mot evidensbaserad terapi vid primär systemisk vaskulit. De senaste decenniernas framsteg har gett dagens patienter bättre läge

The prospects for patients suffering from systemic small vessel vasculitis have improved substantially in recent decades. The introduction of cyclophosphamide in the 1970s led to a dramatic improvement in survival rates. The discovery of ANCA meant a substantial increase in the number of detected cases, especially among elderly patients, as well as detection at an earlier stage of disease. At the

Designing pipeline FFT processor for OFDM (de)modulation

The FFT processor is one of the key components in the implementation of wideband OFDM systems. Architectures with a structured pipeline have been used to meet the fast, real-time processing demand and low-power consumption requirement in a mobile environment. Architectures based on new forms of FFT, the radix-2i algorithm derived by cascade decomposition, is proposed. By exploiting the spatial reg

De-centering state making : Comparative and international perspectives

Bridging the gap between international relations and comparative politics, this book transposes Eurocentric theories and narratives of state-making to new historical and geographical contexts in order to probe their scope conditions. In doing this, the authors question received explanations of the historical origins and geographical limits of state-making, questioning the unilinear view of the eme

De-Centering Federal Origins: India and the Contested Appropriation of Federal Democracy

The chapter explores conceptions during the early twentieth century regarding the required and desired underpinnings of a post-imperial India – one in which both British India and the indirectly ruled princely states were first, by the British, proposed and then, through the work of the Indian Constituent Assembly, made to constitute a federation. It specifically enquires into India’s federal orig