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Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

A Simulation Study Quantifying the Effects of Drive Cycle Characteristics on the Performance of a Pneumatic Hybrid Bus

In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c

The feasibility of using Pareto fronts for comparison of treatment planning systems and delivery techniques

Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves

Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course of disease in a mouse model of intragastric E. coli O157:H7 inoculation. Intraperitoneal administrat

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Practical Aspects of Reduced Complexity LDPC Decoding using Forced Convergence

This thesis is an extension to the previous work done at Department of EIT in investigating the complexity reduction of LDPC decoding using the stochastic approximation method to improve the energy efficiency of energy-limited applica- tions, such as in mobile phones. The research carried out in this thesis investigates the complexity and conver- gence results of adaptive performance control algorit

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SOLOMON ISLANDS NATIONAL LAW AND POLICY REPORT CONSULTATION DRAFT 2020 Displacement in the Context of Disasters and Climate Change Funded by This report was prepared by Joseph Foukona (USP), Victor Bernard (RWI) and Matthew Scott (RWI) 2020 TABLE OF CONTENTS 1 INTRODUCTION 1 1.1. A human rights-based approach 1 2 Displacement in Numbers 3 2.1. Number of disasters and people affected in the last te

https://rwi.lu.se/wp-content/uploads/2024/03/Consultation-Draft_Solomon-Islands.pdf - 2026-05-04

2. ehealth trends possibilities challenges henrik ahlen

eHealth_Trends_possibilities_challenges_Henrik_Ahlen2 The Digital Transformation 
 eHealth for clinical benefit Henrik Ahlén eHealth Strategist - Sopra Steria Sweden
 blog eHealth: www.alfabravo.com 
 Trends, possibilities and challenges in e-Health
 Henrik Ahlen is managing development projects for digital health services. From needs analysis and concept development to implementation. Blogging ab

https://www.ludc.lu.se/sites/ludc.lu.se/files/2._ehealth_trends_possibilities_challenges_henrik_ahlen.pdf - 2026-05-07

Så blir vardagen trådlös med 5G

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. 5G handlar inte bara om snabbare surf. En minst lika stor ”game changer” är att 5G gör mer kommunikation trådlös än idag. Forskaren Emma Fitzgerald listar prylarna som kan kopplas upp - och de tekniska utmaningar som först måste lösas för att förändringen verkligen ska hända. Teknikskiften förändrar samhället, hur v

https://www.lu.se/artikel/sa-blir-vardagen-tradlos-med-5g - 2026-05-06

Factors associated with good health among older persons who received a preventive home visit : a cross-sectional study

Background: The ageing population is increasing worldwide, and this trend is bringing challenges both for the older person and for society. In order to meet the challenges a comprehensive approach is needed involving both health promotion and risk prevention. The preventive home visit is a public health intervention used around the world with the purpose of promoting health and preventing risk amo

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Master’s Dissertation Structural Mechanics JIMMY PERSSON Report TV SM -5181 JIM M Y PERSSO N N U M ER IC A L A N A LY SIS O F C O M PR ESSIO N PER PEN D IC U LA R TO TH E G R A IN IN G LU LA M B EA M S W ITH A N D W ITH O U T R EIN FO R C EM EN T NUMERICAL ANALYSIS OF COMPRESSION PERPENDICULAR TO THE GRAIN IN GLULAM BEAMS WITH AND WITHOUT REINFORCEMENT Detta är en tom sida! Copyright © 2011 by Str

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5181.pdf - 2026-05-04

Ladd

Ladd What is prosody, anyway? Bob Ladd, University of Edinburgh Widespread use of the term prosody in linguistics dates only from the 1970s. Up until then, the term’s primary meaning concerned rules of poetic metre and other aspects of text-setting and poetic well-formedness. The shift from the poetic sense to the term’s current meaning began in the late 1960s and was more or less complete by abou

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_bruce-2014/Ladd.pdf - 2026-05-04

Vårterminen 2024

Här hittar du som är student eller medarbetare hos oss information om valbara kurser, kalendarium för hela terminen. JanuaryWeek 3: 15-21 January15.1    Official start of spring semester15.1     MFAAR meeting 10.00-11.0015.1     Meeting with the exchange students 11.00-11.3015.1    ALL STUDENTS 12.00-13.00 Student forum with lunch WELCOME TO NEW SEMESTER 19.1    Application portal BFA and MFA prog

https://www.khm.lu.se/varterminen-2024 - 2026-05-05

Entrepreneurial Ownership and New Venture Finance

Ownership and finance are crucial for governance, decision-making, and strategic objectives in entrepreneurial ventures. They affect how firms raise capital, scale, and navigate risks, ultimately impacting both success and sustainability. By examining ownership structures in relation to emerging financing models like equity crowdfunding, ICOs, and blockchain-based solutions, our research provides

https://www.lusem.lu.se/organisation/research-centres/sten-k-johnson-centre-entrepreneurship/research-sten-k-johnson-centre-entrepreneurship/entrepreneurial-ownership-and-new-venture-finance - 2026-05-05

Symptoms and Diagnoses Prior to Suicide in Children and Young Adults—A Swedish Medical Record Review

Suicide in children and young adults is a leading cause of premature mortality, and there is a need to develop a more profound understanding of the factors that contribute to these deaths. This study is part of the nationwide Retrospective Investigation of Health Care Utilization in Individuals who died by Suicide in Sweden 2015, conducted at Lund University, Sweden. The aim was to examine symptomSuicide in children and young adults is a leading cause of premature mortality, and there is a need to develop a more profound understanding of the factors that contribute to these deaths. This study is part of the nationwide Retrospective Investigation of Health Care Utilization in Individuals who died by Suicide in Sweden 2015, conducted at Lund University, Sweden. The aim was to examine symptom

Så kan man använda militära strategier mot cancer

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Kan militära strategier användas som inspiration för cancerforskning? Ja, det föreslår i alla fall professor David Gisselsson Nord, patolog och cancerforskare i Lund tillsammans med professor Robert Egnell, strateg på Försvarshögskolan, Stockholm i en nyligen publicerad artikel i tidskriften Trends in Cancer. - Det

https://www.lu.se/artikel/sa-kan-man-anvanda-militara-strategier-mot-cancer - 2026-05-05

MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec