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Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress

Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e. unfolded protein response (UPR), play key roles in proteostasis but their involvement in t

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Lägg till titel FÖRSÄTTSSIDA STYRDOKUMENT Kvalitetspolicy för Lunds universitet Typ av styrdokument: Policy Definition av typen av styrdokument: En policy uttrycker ledningens övergripande viljeriktning eller värden som ska beaktas inom det område policyn omfattar och sätter ramarna för ett visst handlande och utgör en stark rekommendation om ett visst handlingssätt. Beslutsfattare: Universitetsst

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/Kvalitetsarbete/Kvalitetspolicy_f%C3%B6r_Lunds_universitet.pdf - 2026-05-02

Kvalitetspolicy för Lunds universitet. Beslut 2024-10-22.

Lägg till titel FÖRSÄTTSSIDA STYRDOKUMENT Kvalitetspolicy för Lunds universitet Typ av styrdokument: Policy Definition av typen av styrdokument: En policy uttrycker ledningens övergripande viljeriktning eller värden som ska beaktas inom det område policyn omfattar och sätter ramarna för ett visst handlande och utgör en stark rekommendation om ett visst handlingssätt. Beslutsfattare: Universitetsst

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2024-11/Kvalitetspolicy%20fo%CC%88r%20Lunds%20universitet.pdf - 2026-05-03

Methane fluxes from a small boreal lake measured with the eddy covariance method

Fluxes of methane, CH4, were measured with the eddy covariance (EC) method at a small boreal lake in Sweden. The mean CH4 flux during the growing season of 2013 was 20.1 nmol m−2 s−1 and the median flux was 16 nmol m−2 s−1 (corresponding to 1.7 mmol m−2 d−1 and 1.4 mmol m−2 d−1). Monthly mean values of CH4 flux measured with the EC method were compared with fluxes measured with floating chambers (

Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen

Autoantibody-mediated diseases comprise a heterogeneous group of disorders in which the pathogenic potential of autoantibodies has been clearly demonstrated. In general, their treatment relies on the long-term use of systemic corticosteroids and other immunosuppressants that are associated with considerable adverse reactions. EndoS, an endoglycosidase derived from Streptococcus pyogenes, specifica

Development of asymmetrical flow field-flow fractionation-multi angle laser light scattering analysis for molecular mass characterization of cationic potato amylopectin

The goal of this study is to investigate the applicability of asymmetrical flow field-flow fractionation (AsFlFFF)–multi angle laser light scattering (MALLS), and to develop a method for analysis of cationic potato amylopectin (CPAP) having ultrahigh molecular mass (UHMr). Use of the aqueous carrier having low salt content (3 mM NaN3) resulted in a distortion in AsFlFFF fractograms of CPAP with a

Rapid prediction of soil hydraulic and physicochemical properties using the Nix Pro color sensor

Color is the most obvious and easily determined soil property that can provide crucial information about soil composition. The NIX™ Pro color sensor (Nix) presents a user-friendly alternative to the traditional Munsell manual method, with reduced sensitivity to environmental and human factors. Therefore, a new method was developed to use Nix in combination with machine learning to quickly and affo

New NanoLundian investigating clay materials at an atomistic level

Clay is described as an ancient material with a great future. “The potential areas of application are huge,” says an enthusiastic Marie Skepö, professor of theoretical chemistry whom we recently welcomed as an affiliated faculty member of NanoLund. Clay is a material that has been used since ancient times for protecting, building, and carrying things. If we learn more about how to change various p

https://www.nano.lu.se/article/new-nanolundian-investigating-clay-materials-atomistic-level - 2026-05-01

Antibacterial Fusion Proteins Enhance Moraxella catarrhalis Killing

Moraxella catarrhalis is a human-specific commensal of the respiratory tract and an opportunistic pathogen. It is one of the leading cause of otitis media in children and of acute exacerbations in patients with chronic obstructive pulmonary disease, resulting in significant morbidity and economic burden. Vaccines and new immunotherapeutic strategies to treat this emerging pathogen are needed. Comp

Human igg increases virulence of streptococcus pyogenes through complement evasion

Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia. This gram-positive bacterium has developed several strategies to evade the human immune system, enabling S. pyogenes to survive in the host. These strategies include recruiting several human plasma proteins, such as the complement inhibitor, C4b-binding prot

The bone morphogenetic proteins antagonist noggin inhibits membranous ossification

Bone morphogenetic proteins (BMPs) are expressed and secreted during fracture repair. Although they are likely to be required for this process, little is known about their physiological role in bone regeneration. Noggin is a protein that specifically binds and inactivates several BMPs, It plays fundamental roles during early embryonal development and limb morphogenesis by this BMP-inactivating act

Determination of carbonate-C in biochars

Although carbonate-carbon (C), an integral part of biochar-C, contributes to the liming properties of that material, it also interferes with the estimation of the stable organic C fraction in biochars. In this study, four methods were compared in order to quantify the carbonate-C in biochars: two direct (a titrimetric procedure and thermogravimetric analysis, TGA), and two indirect (acid treatment