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Peptides representing the C-terminal end of secretin were synthetized and their effects tested along with secretin on column-perifused isolated mouse pancreatic islets. Insulin release induced by 10 mmol/l D-glucose was potentiated by secretin tested in a concentration range of 0.01-10 μg/ml; the maximal effect was obtained with 1 μg/ml secretin. This effect was mimicked by 50-500 μg/ml NH2-Leu-Le

Blood mononuclear cells obtained from 17 newly diagnosed insulin-dependent diabetic (IDDM) patients treated with insulin for 5-7 days were assessed for the number of spontaneous and pokeweed mitogen (PWM)-stimulated immunoglobulin-secreting cells in a reverse haemolytic plaque assay. The spontaneous in vitro immunoglobulin secretion was evanescent and decreased in individual patients within 1-4 mo

Purpose: The purpose of this study was to evaluate whether an educational palliative care intervention improved the quality of life for next of kin to older persons in nursing homes. Methods: Altogether, 90 next of kin in the intervention group and 105 next of kin in the control group were included. Data were collected using the WHOQOL-BREF questionnaire, answered before and 3 months after the int

To evaluate the association between mild acute cellular rejection (ACR) and the development of cardiac allograft vasculopathy (CAV) after heart transplantation (HTx). Substudy of the SCHEDULE trial (n = 115), where de novo HTx recipients were randomized to (i) everolimus with early CNI elimination or (ii) CNI-based immunosuppression. Seventy-six patients (66%) were included based on matched intrav

Diarrhoeal disease is the second leading cau- se of death in children under five years old, and is responsible for killing around 525 000 children every year. The spread of diseases is also a problem in our western society. Thanks to our developed me- dical infrastructure not to the extent as in de- veloping countries. Nevertheless the amount of work and school hours missed because of preven

Inadequate water infrastructural development and high costs of water are few of the many challenges that affect water access in Kibera. Consequently, many alternatives to piped water grew out of necessity to meet the needs of residents. The aim of this thesis is to examine the conditions that have led to poor water provision in Kibera and how transitions to improved water access can be achieved by

Author: Ebba Eiroff Title: Students narratives of loneliness Supervisor: Kristina Göransson Assessor: Mats Hilte The aim for this qualitative study was to examine university students experiences of loneliness based on Erving Goffman’s dramaturgy theory, together with the conceptions of normality, shame and guilt. How students describe feelings of loneliness and how they relate their experiences t

This master thesis is commissioned by the company Haldex Brake Products AB based in Landskrona. The company is acting on the road vehicle market. Amongst other products the company produces disc brakes for the heavy road vehicle industry. Disc brakes developed by Haldex, based on the sliding caliper principle, are during certain circumstances experiencing problems with malfunction of the brake due

In Sweden, hypertension, is one of the most common reasons to attend primary care thus a Swedish public health problem of epic proportions. There is a general consensus about that effective antihypertensive treatment reduces the risk of developing cardiovascular diseases and premature death. Non-pharmacological treatment is advocated to be the basis of treatment. The caregiver is responsible for s

Over the course of almost four decades the world has been left vulnerable by the HIV epidemic. Displaying the biggest public health challenge currently, many scholars aim to further the understanding of the mechanisms of the spread of HIV. This study aims to contribute to the existing body of literature through adding a spatial aspect to research performed on HIV key drivers in Uganda. Furthermore

A sample of 107 asset sales completed globally from October 2006 to January 2019 has been investigated to find the average discount at which the assets of distressed energy companies are liquidated. In the next step, the difference in difference approach has been used to explore the oil price crash in the fourth quarter of 2014 so as to find the difference in the average discount on the assets of

An inverse class D power amplifier and a class A power amplifier are designed at schematic level for 20 dBm power class and NB-IoT specification in 65 nm CMOS technology. A suitable switch mode supply modulator is also designed. Three different efficiency enhancement techniques namely EER, Hybrid EER and ET are studied and the suitable transmitters are simulated for each in Cadence Virtuoso. These

Background: To study the diabetes related CVD risk between men and women of different ages. Methods: Hazards ratios (HRs) (95%CI) for acute CHD and ischaemic stroke events were estimated based on data of Finnish and Swedish cohorts of 5111 women and 4167 men. Results: 182 (3.6%) women and 348 (8.4%) men had CHD and 129 (2.5%) women and 137 (3.3%) men ischaemic stroke events. The multivariate adjus

Increasing precipitation and surface water temperature due to global change may strengthen the salinity gradient in coastal regions, which could influence the behaviour of dinoflagellate migration. We studied diel vertical migration (DVM) behaviour in the dinoflagellates Prorocentrum minimum and Heterocapsa triquetra using vertically stratified laboratory columns with 3 different salinity gradient

The REVEALS model was developed to reconstruct quantitatively regional vegetation abundance (in a 10(4)-10(5) km(2) area) from pollen assemblages in large lakes (>= 100-500 ha). This model corrects for biases in pollen percentages caused by inter-taxonomic differences in pollen productivity and dispersal. This paper presents the first case study to validate REVEALS, using empirical data from south

Great Spotted and Syrian Woodpeckers (Dendrocopos major and D. syriacus) are known to hybridize in nature; however, the extent of this phenomenon is not known due to difficulties in hybrid detection based on plumage analyses. Here, we tested five markers (one mitochondrial and four nuclear) and a set of six microsatellite loci for the identification of these two Woodpeckers and their hybrids. Sequ

Background: To explore the point prevalence of the risk of malnutrition and the targeting of nutritional interventions in relation to undernutrition risk and hospital volume. Methods: A cross-sectional survey performed in nine hospitals including 2 170 (82.8%) patients that agreed to participate. The hospitals were divided into large, middle, and small sized hospitals. Undernutrition risk and over