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Background Effective cooperation between B-cells and T-cells within the tumor microenvironment may lead to the regression of established tumors. B-cells and T-cells can recognize tumor antigens with exquisite specificity via their receptor complexes. Nevertheless, whether a diverse intratumoral B-cells and T-cell receptor (BCR, TCR) repertoire affects the tumor immune microenvironment (TIME) and c

Meeting stricter legal emission limits and the simultaneous introduction of new synthetic fuels are key challenges for current and future research in the field of engine combustion. A deep knowledge of spray behavior is mandatory to address these problems, as air‐fuel mixture and spray propagation in gasoline direct injection (GDI) are essential processes to achieve a highly efficient and clean co

BACKGROUND CONTEXT: Degenerative cervical spondylotic myelopathy (DCM) is the commonest form of spinal cord injury in adults. However, a limited number of clinical reports have assessed the role of biomarkers in DCM. PURPOSE: We evaluated cerebrospinal fluid (CSF) biomarkers in patients scheduled for DCM surgery and hypothesized that CSF biomarkers levels (1) would reflect the severity of preopera

T-cell development provides an excellent model system for studying lineage commitment from a multipotent progenitor. The intrathymic development process has been thoroughly studied. The molecular circuitry controlling it has been dissected and the necessary steps like programmed shut off of progenitor genes and T-cell genes upregulation have been revealed. However, the exact timing between decisio

Recent work has shown that 8-bit floating point (FP8) can be used for efficiently training neural networks with reduced computational overhead compared to training in FP32/FP16. In this work, we investigate the use of FP8 training in a federated learning context. This brings not only the usual benefits of FP8 which are desirable for on-device training at the edge, but also reduces client-servercom

Syftet med denna studie är att utifrån mitt empiriska material kartlägga och beskriva hur föräldrar till barn intagna på särskilda ungdomshemmen tolkar, definierar och upplever ett behandlingsprojekt, som involverade olika myndigheter, benämnt Motverka Våld och Gäng. Dessutom uppmärksammas hur de anställda samordnarna uppfattades och kategoriserades av föräldrarna. ”Föräldrar” blir i undersökninThe aim of this study is to analyze how mothers with children placed in Swedish juvenile homes interpret, define and perceive, on the one hand, the project “Motverka Våld och Gäng” meaning “Counteract Violence and Gangs”, and on the other hand the role of the Coordinators employed in this project. The mothers who were interviewed spoke about some Coordinators that they appreciated. They then pain

Attention Restoration Theory point to nature as a particularly good candidate for restoring the ability to focus and inhibit distractions. However, little effort has been directed to elaborating on what makes nature's visual pattern unique for restoration purposes. One suggested explanation is the fractal properties of natural patterns (Hagerhall, 2005). Both perception studies (Hagerhall et al.,

Background: Cognitive deficits are common and disabling residual symptoms following major depressive disorder (MDD) and are related to increased risk of relapse. Residual cognitive deficits should thus be considered an important target for treatment. However, few have reported long-term outcomes of interventions targeting residual cognitive deficits. Objective: This study aimed to (1) investigate