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This article discusses an important panel held at ICIS 2011 in Shanghai to mark over thirty years of an ICIS institution, the ICIS Women's Breakfast. The panel addressed the controversial question-is there still a need for the ICIS Women's Breakfast? Panelists were asked if the ICIS Women's Breakfast could be seen as divisive, and if women's issues are different from issues of diversity such as ra
Background Effective cooperation between B-cells and T-cells within the tumor microenvironment may lead to the regression of established tumors. B-cells and T-cells can recognize tumor antigens with exquisite specificity via their receptor complexes. Nevertheless, whether a diverse intratumoral B-cells and T-cell receptor (BCR, TCR) repertoire affects the tumor immune microenvironment (TIME) and c
Meeting stricter legal emission limits and the simultaneous introduction of new synthetic fuels are key challenges for current and future research in the field of engine combustion. A deep knowledge of spray behavior is mandatory to address these problems, as air‐fuel mixture and spray propagation in gasoline direct injection (GDI) are essential processes to achieve a highly efficient and clean co
In an explorative manner, this article uses a data-driven digital history set-up to focus on how the Swedish Riksdag, its political parties and parliament members discussed media issues. By distant reading and topic modeling a dataset of more than 11,000 parliamentary minutes – approximately 400 million characters – the article gives a new perspective of Swedish media history in general and nation
Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stress and emotional states in caregivers. We here report mitochondrial RC activities, mitochondrial DNA copy number (mtDNAcn), and the composite MHI in unmedicated and
Present debates suppose a close linkage between economic, social, and environmental sustainability and suggest that individual wellbeing and living standards need to be understood as directly linked to environmental concerns. Because social movements are often seen as an avant-garde in pushing for change, this article analyzes climate protesters' support for three key frames in current periods of
Geospatial data are increasingly available nowadays, and this leads to more analyses and visualisation of geospatial data from several sources. To enable this, we need homogenous data as well as proper integration methods. Geospatial data integration has been a longstanding research topic for decades, and this paper discusses the utilisation of Linked Data technology stack to alleviate the geospat
Using NMR and Monte Carlo (MC) methods, we investigate the stability and dynamics of superoxide dismutase 1 (SOD1) in homogeneous crowding environments, where either bovine pancreatic trypsin inhibitor (BPTI) or the B1 domain of streptococcal protein G (PGB1) serves as a crowding agent. By NMR, we show that both crowders, and especially BPTI, cause a drastic loss in the overall stability of SOD1 i
T-cell development provides an excellent model system for studying lineage commitment from a multipotent progenitor. The intrathymic development process has been thoroughly studied. The molecular circuitry controlling it has been dissected and the necessary steps like programmed shut off of progenitor genes and T-cell genes upregulation have been revealed. However, the exact timing between decisio
Background: Information is scarce on long-term changes in energy intake (EI), dietary energy density (DED), and body composition in adolescents undergoing laparoscopic Roux-en-Y gastric bypass (RYGB). Objectives: To investigate long-term changes in EI, DED, and body composition in adolescents after LRYGB. Setting: University hospitals, multicenter study, Sweden. Methods: Eighty-five adolescents (6
It is well known that certain cancers have shown clusteringin educational and socioeconomic groups, but recent comprehensive data on clustering by education are limited. We determined standardized incidence ratios (SIRs), adjusted for several variables, for cancer among men and women in six educational groups based on the Swedish Family-Cancer Database. People were identified with a certain educat
The measurement of potential enzymatic activities has been proposed as an efficient method to infer nutrient limitations for microorganisms in environmental samples. To validate this use, confirmation with direct methods of microbial growth responses to resource additions are required. We experimentally manipulated nutrient-poor soils from the afromontane subtropics with relatively low (grassland
The aim of this study was to explore the usefulness of research circle methodology in the later stages of the research process. In an active collaboration with the researchers, participants, that is, users of research, discussed and prioritized research on home and health dynamics. Reflections, comments, and evaluations from both leaders and users were analyzed, applying content analysis. The usef
A numerical simulation is performed to identify the material parameters of an elastic/visco-plastic material under tensile impact loading. The identification is based on an inverse analysis using the Kalman filter technique and the finite element method. The input data to the inverse analysis are the time histories of the strains on specimens. The measurement errors can be treated reasonably by thA numerical simulation is performed to identify the material parameters of an elastic/visco-plastic material under tensile impact loading. The identification is based on an inverse analysis using the Kaiman filter technique and the finite element method. The input data to the inverse analysis are the time histories of the strains on specimens. The measurement errors can be treated reasonably by th
