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New neurons are continuously generated from neural stem cells with astrocyte properties, which reside in close proximity to the ventricle in the postnatal and adult brain. In this study we found that microRNA-124 (miR-124) dictates postnatal neurogenesis in the mouse subventricular zone. Using a transgenic reporter mouse we show that miR-124 expression is initiated in the rapid amplifying progenit
Aims: This study aimed to examine the population-based Skåne Health-care Register (SHR) regarding feasibility for scientific research and also strengths and weaknesses. Methods: To analyse the feasibility of the SHR, we performed a bibliographic search for peer-reviewed articles based on SHR data from 2000 to 2018. To analyse strengths and weaknesses, we used original SHR data about coverage and v
BACKGROUND: Globally, 700 000 people die every year by suicide. Health care consultation patterns the period before suicide could be one potential way to identify people at risk for suicide. Therefore, this study examines health care patterns up to one year prior to the suicide by age, sex and prior diagnoses and specifically investigates if and how this differs from the general population of Skån
Although invasive species are recognized as a major threat to freshwaters, little is known about how future climate warming will affect the success of invaders. Ecosystems are also often simultaneously impacted by multiple, potentially interacting, invading species and the management of species invasions can be incredibly difficult. Sensitive methods such as environmental DNA (eDNA) metabarcoding,
IMPORTANCE The clinical management of BRCA1 and BRCA2 mutation carriers requires accurate, prospective cancer risk estimates. OBJECTIVES To estimate age-specific risks of breast, ovarian, and contralateral breast cancer for mutation carriers and to evaluate risk modification by family cancer history and mutation location. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study of 6036 BRCA1 and
During memory formation, structural rearrangements of dendritic spines provide a mean to durably modulate synaptic connectivity within neuronal networks. New neurons generated throughout the adult life in the dentate gyrus of the hippocampus contribute to learning and memory. As these neurons become incorporated into the network, they generate huge numbers of new connections that modify hippocampa
NGEM01_Master_thesis_Felix_Martin_Hofmann Student thesis series INES nr Glacial history of the upper Drac Blanc catchment (Écrins massif, French Alps) Felix Martin Hofmann 2018 Department of Physical Geography and Ecosystem Science Lund University Sölvegatan 12 S-223 62 Lund Sweden Felix Martin Hofmann (2018). Glacial history of the upper Drac Blanc catchment (Écrins massif, French Alps) Glaciatio
https://www.nateko.lu.se/sites/nateko.lu.se/files/ngem01_master_thesis_felix_martin_hofmann_1.pdf - 2026-05-10
Artificial intelligence (AI) applications are increasingly seeing use in breast imaging, particularly to assist in or automate the reading of mammograms. Another novel technique is mechanical imaging (MI) which estimates the relative stiffness of suspicious breast abnormalities by measuring the distribution of pressure on the compressed breast. This study investigates the feasibility of combining
Diabetic muscle atrophy is an inflammation-related complication of type-2 diabetes mellitus (T2DM). Even though regular exercise prevents further deterioration of atrophic status, there is no effective mediator available for treatment and the underlying cellular mechanisms are less explored. In this study, we investigated the therapeutic potential of MCC950, a specific, small-molecule inhibitor of
Aim/hypothesis: Human enteroviral infections are suggested to be associated with type 1 diabetes. However, the mechanism by which enteroviruses can trigger disease remains unknown. The present study aims to investigate the impact of enterovirus on autophagy, a cellular process that regulates beta cell homeostasis, using the clonal beta cell line INS(832/13) and human islet cells as in vitro models
Vägar slits konstant och kräver konstant förbättringar och ombyggnationer. För att möjliggöra detta krävs personer som befinner sig ute på vägarna. Tekniken har gått framåt inom området trafiksäkerhet men skulle behöva förbättras ytterligare om vägarbetare ska vara säkra på sin arbetsplats. Även trafiken har förändrats över åren. Idag finns fler fordon på vägarna än aldrig förr. Bilarna är säkrareRoads are constantly worn down and demands improvements and reconstructions. To make this possible there has to be road workers on the road. Road safety has been improved along the years but can still be improved more. Today there are more vehicles on the road than ever before. The cars are more safe and therefore is encouraging to higher speeds as they are driven together with all safety features
Inom marknadsföring är det en ständig kamp att framställa varumärken som det bästa där det är vanligt att locka med diverse gåvor och belöningar för att försöka få lojala kunder. Syftet med studien var att undersöka om en belöning (choklad) kunde påverka studenters attityd gentemot designen på olika reklambilder. Närmare bestämt om attityden kunde påverkas av belöningen men också om det skiljer siWithin marketing there is a constant struggle to promote brands as the best and it is common practice to promise various gifts and rewards in an attempt to attract loyal customers. The purpose of the study was to investigate whether a reward (chocolate) could influence students' attitudes towards different ads. Specifically, if the attitude could be influenced by the reward but also if it diff
This study focus on the six largest minable cryptocurrencies: Bitcoin, Bitcoin Cash, Litecoin, Ethereum, Monero and DASH, and puts forward determinants that explain large parts of the price value formation in the markets. This is done by Ordinary Least Squares linear regression with intent to validate or question previous research regarding explanatory factors driving the market price. These facto
Det förekommer kommersiella standardavtal och konsumentstandardavtal. Införlivandet av standardvillkor saknar lagstiftning i både hänseenden. Högsta domstolens avgöranden är därför den primära rättskällan för utvecklingen. Konsumentavtal omfattas däremot av tvingande lagstiftning som har till syfte att skydda konsumenter från oskäliga avtalsvillkor. Standardavtalsrätten är central utgångspunkt förThere are commercial standard contracts and consumer standard agreements. The incorporation of standard terms lacks legislation in both respects. The ruling of the Supreme Court is therefore the primary source of law for development. Consumer contracts, on the other hand, are covered by mandatory legislation whose purpose is to protect consumers from unfair contract terms. The standard contract la
