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Preoperative Electrophysiology in Patients With Ulnar Nerve Entrapment at the Elbow-Prediction of Surgical Outcome and Influence of Age, Sex and Diabetes

The impact of preoperative electrophysiology on outcome of surgical treatment in ulnar nerve entrapment at the elbow (UNE) is not clarified. Our aim was to evaluate influence of preoperative electrophysiologic grading on outcome and analyse how age, sex, and in particular diabetes affect such grading. Electrophysiologic protocols for 406 UNE cases, surgically treated at two hand surgery units repo

The risk for venous thromboembolism and cardiometabolic disorders in offspring from thrombosis-prone pedigrees

Background: Most family studies on venous thromboembolism (VTE) have focused on first-degree relatives. Objectives: We took a pedigree-based approach and examined the risk of VTE and cardiometabolic disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods: From the Swedish population, we identified a total of 482 185 pedigrees containing a mean of 14.2

Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS

Background: Polycystic ovary syndrome's (PCOS) main feature is hyperandrogenism, which is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue and skeletal muscle reveal dysregulated metabolic pathways in women with PCOS, but these differences do not necessarily lead to changes in protein levels and biological function. Methods: To advance our understanding of

Superfluid-droplet crossover in a binary boson mixture on a ring : Exact diagonalization solutions for few-particle systems in one dimension

We investigate the formation of self-bound quantum droplets in a one-dimensional binary mixture of bosonic atoms, applying the method of numerical diagonalization of the full Hamiltonian. The excitation spectra and ground-state pair correlations signal the formation of a few-boson droplet when crossing the region of critical interspecies interactions. The self-binding affects the rotational excita

Regulation of insulin secretion in diabetes: Molecular mechanism and applications

Diabetes is a highly ageing-related disease manifesting with a deteriorated capacity of insulin secretion and uncontrolled blood glucose-raising, hyperglycemia. In this thesis, we aim to explore the underlying roles of CaV channels and aging-associated genetic changes in the development of Type 2 diabetes (T2D).In pancreatic β-cells, the active of voltage-gated calcium (CaV) channels play an essen

Universality class of a spinor Bose–Einstein condensate far from equilibrium

Scale invariance and self-similarity in physics provide a unified framework for classifying phases of matter and dynamical properties near equilibrium in both classical and quantum systems. This paradigm has been further extended to isolated many-body quantum systems driven far from equilibrium, for which the physical observables exhibit dynamical scaling with universal scaling exponents. Universa

Photon emission statistics of a driven microwave cavity

Recent experimental advances have made it possible to detect individual quantum jumps in open quantum systems, such as the tunneling of single electrons in nanoscale conductors or the emission of photons from nonclassical light sources. Here, we investigate theoretically the statistics of photons emitted from a microwave cavity that is driven resonantly by an external field. We focus on the differ

Highly sensitive humidity sensor based on cadmium selenide quantum dots-polymer composites : synthesis, characterization, and effect of UV/ozone treatment

This work describes the rational design of thin film-based cadmium selenide quantum dots (CdSe) mixed with conductive polyvinylidene fluoride (PVDF), inducing PVDF-CdSe composite for potential resistive humidity-sensing applications. The effect of UV/ozone treatment on surface hydrophilicity and sensing properties was investigated. AFM has been performed to examine the prepared films' texture, dis

Opioid dispensing in relation to arthroscopic knee surgery in Denmark from 2006 to 2018

INTRODUCTION. In the US, opioids are commonly prescribed after arthroscopic knee surgery. We aimed to investigate opioid dispensing in relation to arthroscopic knee surgeries from 2006 to 2018 in Denmark. METHODS. In Danish registries, we identified patients (≥ 15 years old) having arthroscopic knee surgery (anterior cruciate ligament (ACL) reconstruction; meniscal surgery; cartilage resection; sy

Airway contraction and cytokine release in isolated rat lungs induced by wear particles from the road and tire interface and road vehicle brakes

The dominant road traffic particle sources are wear particles from the road and tire interface, and from vehicle brake pads. The aim of this work was to investigate the effect of road and brake wear particles on pulmonary function and biomarkers in isolated perfused rat lungs. Particles were sampled from the studded tire wear of three road pavements containing different rock materials in a road si

Perspectives of current understanding and therapeutics of Diamond-Blackan anemia

Diamond-Blackfan anemia (DBA) is a rare congenital bone marrow failure disorder characterized by erythroid hypoplasia. It primarily affects infants and is often caused by heterozygous allelic variations in ribosomal protein (RP) genes. Recent studies also indicated that non-RP genes like GATA1, TSR2, are associated with DBA. P53 activation, translational dysfunction, inflammation, imbalanced globi

Probe thermometry with continuous measurements

Temperature estimation plays a vital role across natural sciences. A standard approach is provided by probe thermometry, where a probe is brought into contact with the sample and examined after a certain amount of time has passed. In situations where, for example, preparation of the probe is non-trivial or total measurement time of the experiment is the main resource that must be optimized, contin

Rationalizing Performance Losses of Wide Bandgap Perovskite Solar Cells Evident in Data from the Perovskite Database

Metal halide perovskites (MHPs) have become a widely studied class of semiconductors for various optoelectronic devices. The possibility to tune their bandgap (Eg) over a broad spectral range from 1.2 eV to 3 eV by compositional engineering makes them particularly attractive for light emitting devices and multi-junction solar cells. In this metadata study, data from Peer-reviewed publications avai

Snack quality and snack timing are associated with cardiometabolic blood markers : the ZOE PREDICT study

Background: Snacking is a common diet behaviour which accounts for a large proportion of daily energy intake, making it a key determinant of diet quality. However, the relationship between snacking frequency, quality and timing with cardiometabolic health remains unclear. Design: Demography, diet, health (fasting and postprandial cardiometabolic blood and anthropometrics markers) and stool metagen

Gaining control on optical force by the stimulated-emission resonance effect

The resonance between an electronic transition of a micro/nanoscale object and an incident photon flux can modify the radiation force exerted on that object, especially at an interface. It has been theoretically proposed that a non-linear stimulated emission process can also induce an optical force, however its direction will be opposite to conventional photon scattering/absorption processes. In t

The escape from hunger: The impact of food prices on well-being in Sweden, 1813–1967

This study analyses how the standard of living for different social groups changed when Sweden developed from an agricultural to an industrial society and when the first steps towards a modern welfare society were taken. As a measure of living standards, we use the ability to overcome short-term economic stress caused by high food prices. We use individual-level longitudinal data from 1813 to 1967

Microbial exposure during recycling of domestic waste : a cross-sectional study of composition and associations with inflammatory markers

Objectives This study aims to investigate (1) the microbial community composition by work characteristics and (2) the association between microbial genera level and inflammatory markers among recycling workers. Methods In this cross-sectional study, inhalable dust was collected with personal samplers from 49 production (86 samples) and 10 administrative workers (15 samples). Four groups of micro-o