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Adiabatic elimination and subspace evolution of open quantum systems

Efficient descriptions of open quantum systems can be obtained by performing an adiabatic elimination of the fast degrees of freedom and formulating effective operators for the slow degrees of freedom in reduced dimensions. Here, we perform the construction of effective operators in frequency space, and using the final value theorem or alternatively the Keldysh theorem, we provide a correction for

Lifetime Risk of Visual Impairment Resulting from Glaucoma in Patients Initially Followed up for Elevated Intraocular Pressure

PURPOSE: To report the lifetime risk of visual impairment resulting from glaucoma in patients originally followed up in a 10-year prospective randomized study initiated in 1981 to assess patients with elevated intraocular pressure (IOP).DESIGN: Retrospective patient chart review.PARTICIPANTS: Data on deceased patients who initially were followed up prospectively in the randomized controlled study

Citrus intake and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC)

Citrus intake has been suggested to increase the risk of skin cancer. Although this relation is highly plausible biologically, epidemiologic evidence is lacking. We aimed to examine the potential association between citrus intake and skin cancer risk. EPIC is an ongoing multi-center prospective cohort initiated in 1992 and involving ~ 520,000 participants who have been followed-up in 23 centers fr

Outpatient Treatment in Low-Risk Pulmonary Embolism Patients Receiving Direct Acting Oral Anticoagulants Is Associated With Cost Savings

Direct oral anticoagulants (DOAC) are first line treatment for pulmonary embolism (PE). Treatment of acute PE is traditionally hospital based and associated with high costs. The aims of this study were to evaluate potential cost savings with outpatient DOAC treatment compared to inpatient DOAC treatment in patients with low risk PE. A retrospective study in patients with DOAC treated low risk PE (

Early life exposures and risk of adult respiratory disease during 50 years of follow-up

Adult health is influenced by factors during fetal life affecting organ development and birth weight. We aimed to study such factors in relation to adult respiratory disease (ARD) risk. The Helsingborg Birth Cohort, Sweden, contributed baseline data collected by medical staff through clinical examination and questionnaires on maternal and birth characteristics 1964-1967. Register linkages were per

Changes in health-related quality of life among older adults aging with long-term spinal cord injury

Study design: Cross-sectional and longitudinal. Objectives: To (i) describe health-related quality of life (HRQoL) and changes over 6 years in older adults aging with long-term spinal cord injury (SCI) and (ii) investigate how changes in HRQoL are associated with age, gender, and injury characteristics. Setting: Community in southern Sweden. Methods: From the initial 123 participants (years 2011–2

Pseudo-particle continuum modelling of nanowire growth in aerotaxy

Aerotaxy growth of GaAs nanowires has shown to be capable of making GaAs wires, GaAsxP1-xwires (Metaferia, 2016) and even pn-junctions with phovovoltaic properties. With a goal of better understanding the aerotaxy process, we have developed a model for nanowire growth in Aerotaxy, based on a surface diffusion model for substrate-based growth. Our model considers the growth conditions, varying in t

Leadership perspectives in multidisciplinary team meetings; observational assessment based on the ATLAS instrument in cancer care

Objectives: High-quality leadership and chairing skills are central components in team performance during multidisciplinary team (MDT) meetings. We hypothesized that the recently developed A Tumor Leadership Assessment inStrument (ATLAS) could provide relevant information to support more detailed insights into MDT chairing and leadership aspects of relevance for team feedback and targeted improvem

From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

Cancer is the second leading cause of death among both men and women worldwide. During therecent years, three-dimensional (3D) tumour models have gained increasing interest as a pre-clinicalplatform for screening of compounds for potential use in cancer therapy. It is becoming recognizedthat two-dimensional (2D) cell culturing, in which cells are grown on physiologically irrelevant flatsurfaces, a

Physical mechanism on exciton-plasmon coupling revealed by femtosecond pump-probe transient absorption spectroscopy.

The unclear mechanism of exciton-plasmon coupling interaction in monolayer MoS2-Ag nanoparticles hybrid, as a longstanding target in molecular nanotechnology and catalysis, is systemically investigated with transmission spectra and femtosecond pump-probe transient absorption spectroscopy in this paper. The properties of exciton in monolayer MoS2 are strongly enhanced due to the local surface plasm

The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development

MLL rearrangements are translocation mutations that cause both acute lymphoblastic leukemia and acute myeloid leukemia (AML). These translocations can occur as sole clonal driver mutations in infant leukemias, suggesting that fetal or neonatal hematopoietic progenitors may be exquisitely sensitive to transformation by MLL fusion proteins. To test this possibility, we used transgenic mice to induce

Directed C-H Halogenation Reactions Catalysed by PdII Supported on Polymers under Batch and Continuous Flow Conditions

A new generation of N-heterocyclic carbene palladium(II) complexes containing vinyl groups in different positions in the backbone of the N-heterocycle have been developed. The fully characterised monomers were copolymerised with divinylbenzene to fabricate robust polymer supported NHC-PdII complexes and these polymers were applied as heterogeneous catalysts in directed C-H halogenation of arenes w

Survival, cardiovascular morbidity, and reinterventions after elective endovascular aortic aneurysm repair in patients with and without diabetes : A nationwide propensity-adjusted analysis

Epidemiological data indicate decreased risk for development and growth of abdominal aortic aneurysm (AAA) among patients with diabetes mellitus (DM). On the other hand, DM adds to increased cardiovascular (CV) morbidity and mortality. In a nationwide observational cohort study of patients registered in the Swedish Vascular Register and the Swedish National Diabetes Register, we evaluated potentia

The Role of Hepatic Leukemia Factor in Hematopoiesis

The development of therapeutic methods based on stem cells (e.g. cell therapy, activating regeneration and organ transplantation), known as regenerative medicine, is still a novel area in the field of life sciences. If successful, such therapies could be applicable to many diseases currently lacking effective treatments, such as Parkinson’s disease, diabetes, heart disease or cancer.Stem cells are

Burden of gout in the Nordic region, 1990-2015: findings from the Global Burden of Disease Study 2015

OBJECTIVE: To explore the burden of gout in the Nordic region, with a population around 27 million in 2015 distributed across six countries.METHOD: We used the findings of the 2015 Global Burden of Diseases study to report prevalence and disability associated with gout in the Nordic region.RESULTS: From 1990 to 2015, the number of prevalent gout cases rose by 30% to 252 967 [95% uncertainty interv

Parental health and psychosomatic symptoms in preschool children : A cross-sectional study in Scania, Sweden

Aim: The aim of the study was to assess the association between parental self-rated health and recurrent abdominal pain (RAP) in preschool children. Methods: A questionnaire, including questions about sociodemographic and psychosocial factors, lifestyle, parental and child health, was sent to parents of all 4-year-old children in Scania, Sweden. The response rate was 43.6%. The outcome was RAP and

Smokeless tobacco (snus) use and colorectal cancer incidence and survival : Results from nine pooled cohorts

Aims: Although smoking is considered to be an established risk factor for colorectal cancer, the current evidence on the association between smokeless tobacco and colorectal cancer is scant and inconclusive. We used pooled individual data from the Swedish Collaboration on Health Effects of Snus Use to assess this association. Methods: A total of 417,872 male participants from nine cohort studies a

Model based TDC offset estimation from motored cylinder pressure data

Finding the correct top dead center (TDC) offset for an internal combustion engine is harder than it seems. This paper introduces a novel method to find the TDC offset based on a simple assumption that the heat loss power through the combustion chamber walls is constant for motored cycles in a narrow crank angle interval around TDC. The proposed method uses nonlinear least squares optimization to

A new maximal bicycle test using a prediction algorithm developed from four large COPD studies

Background: Maximum exercise workload (WMAX) is today assessed as the first part of Cardiopulmonary Exercise testing. The WMAX test exposes patients with COPD, often having cardiovascular comorbidity, to risks. Our research project was initiated with the final aim to eliminate the WMAX test and replace this test with a predicted value of WMAX, based on a prediction algorithm of WMAX derived from m