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OBJECTIVE.: Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in several organ systems, related to the presence of circulating and tissue-deposited immune complexes (ICs) which stimulate leukocytes through FcγRs with subsequent inflammation. Treatment with EndoS, an IgG glycan hydrolyzing bacterial enzyme from Streptococcus pyogenes, has shown benefi

Background: Older adults spend more time at home after retirement, and the home becomes a central place for activity. While research indicates that indoor lighting, exposure to daylight, physical activity and sleep interact to influence functioning, mood and daily rhythm, strategies are needed to promote behavioural changes to optimise these factors in daily life. The objective is to design an int

Objectives: This study aimed to describe the clinical experience of the health-care professionals (HCPs) responsible for the introduction of methadone, for the treatment of complex cancer pain, at a low-resource hospital in India in a patient-group, burdened by illiteracy, and low socio-economic status. Materials and Methods: Ten HCPs: Four medical doctors, four nurses, one pharmacist, and one hos

Handbok för systemägare och systemförvaltare vid LU feb 22 Handbok i systemförvaltning FÖR SYSTEMÄGARE OCH SYSTEMFÖRVALTARE | 2022-02-04 BIRGITTA LASTOW 1 Handbok för systemägare och systemförvaltare vid LU Versionshistorik 1.0 2021-02-04 Inför workshop med systemägare/systemförvaltare 2021-02-16 1.1 2022-02-04 Reviderad i förhållande till handbok för IT-SF/IT-SÄ. Tillägg kap 3 Arbetsgrupp: • Kari

https://www.staff.lu.se/sites/staff.lu.se/files/2022-02/Handbok%20f%C3%B6r%20system%C3%A4gare%20och%20systemf%C3%B6rvaltare%20vid%20LU%20feb%2022.pdf - 2026-05-15

Background: Little attention has been given to the risk of cardiovascular and psychiatric comorbidities during the clinical evaluation of a suspected hematological malignancy.Methods: Based on Skåne Healthcare Register, we performed a population-based cohort study of 1,527,449 individuals residing during 2005-2014 in Skåne, Sweden. We calculated the incidence rate ratios (IRRs) of cardiovascular d

OBJECTIVE: To study the association between sperm deoxyribonucleic acid fragmentation index (DFI) and the odds of preeclampsia and other adverse perinatal outcomes after in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment.DESIGN: A prospective cohort study including infertile couples undergoing conventional IVF or ICSI treatment and their children. Data regarding pre

The combustion engine, a well-known source of aerosols, has seen remarkable improvements regarding efficiency and emissions. A drawback of the conventional compression ignition (CI) engine is its requirement for a high cetane number fuel, i.e. diesel which contains long carbon chains forming particulate matter (PM) when combusted in the conventional diesel combustion (CDC) process. A previous stud

Background: Hosts are often simultaneously infected with several parasite species. These co-infections can lead to within-host interactions of parasites, including mutualism and competition, which may affect both virulence and transmission. Birds are frequently co-infected with different haemosporidian parasites, but very little is known about if and how these parasites interact in natural host po

Microsoft Word - Hanna slutversion2008.doc 7 Hanna Gimstedt Som som som En studie av konstruktionen x-som-x* Sammandrag. Uppsatsen är en studie av syntaktiska, semantiska och pragmatiska egenskaper hos konstruktionen x-som-x. Undersökningen tar sin utgångspunkt i den interaktionella grammatiken, och som jämförelsematerial används tidigare undersökningar av konstruktionen x-och-x. Exempel på x-som-

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/Som_som_som.pdf - 2026-05-14

https://rwi.lu.se/news/68035-2/ - 2026-05-14

https://rwi.lu.se/news/page/4/ - 2026-05-14

https://rwi.lu.se/news/page/7/ - 2026-05-14

Ordered arrays of nanocrystals, called supercrystals, have attracted significant attention owing to the collective quantum effects arising from the coupling between neighboring nanocrystals. In particular, lead halide perovskite nanocrystals are widely used because of the combination of the optical properties and faceted cubic shape, which enables the formation of highly ordered supercrystals. The

Background: Selection pressure exerted by pathogens can influence patterns of genetic diversity in the host. In the immune system especially, numerous genes encode proteins involved in antagonistic interactions with pathogens, paving the way for coevolution that results in increased genetic diversity as a consequence of balancing selection. The complement system is a key component of innate immuni

Mito-nuclear insertions, or NUMTs, relate to genetic material of mitochondrial origin that have been transferred to the nuclear DNA molecule. The increasing amounts of genomic data currently being produced presents an opportunity to investigate this type of patterns in genome evolution of non-model organisms. Identifying NUMTs across a range of closely related taxa allows one to generalize pattern

Gal-3 appears clinically useful for ruling out short-term mortality in patients with acute dyspnea and could have role as a negative prognostic marker in the emergency department.

In chronic lymphocytic leukemia (CLL), the microenvironment influences gene expression patterns; however, knowledge is limited regarding the extent to which methylation changes with time and exposure to specific microenvironments. Using high-resolution 450K arrays, we provide the most comprehensive DNA methylation study of CLL to date, analyzing paired diagnostic/follow-up samples from IGHV-mutate

Chronic breathlessness at rest or on minimal exertion despite optimal treatment of the underlying chronic cause(s) is termed chronic refractory breathlessness. This is prevalent across the community and is an independent indicator of poor prognosis. This narrative review focuses on the palliation of chronic refractory breathlessness in people predominantly with non-cancer diagnoses. Breathlessness

Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this hypothesis-generating, secondary analysis was to identify candidate single nucleotide polymorphisms (SNP) from those associated with opioid receptors, signalling or pain modulation to identify any related to

Treatment with melphalan-prednisone-thalidomide improves the outcome of patients with multiple myeloma and is now considered a standard of care for patients not eligible for transplantation. However, this treatment is a major source of morbidity. A meta-analysis of data from individual patients (n=1680) in six randomized trials was performed, comparing the effects of melphalan-prednisone-thalidomi