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Background: Chronic breathlessness adversely impacts people with chronic obstructive pulmonary disease and their caregivers (family and friends), who may, in turn, experience significant burden due to their caregiving role. Sustained-release morphine may reduce chronic breathlessness in some patients, which may have an impact on caregivers’ perceived burden. Aim: To explore the impact on caregiver

The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID-19 severity is unclear. In this population-based, nationwide study using multi-register data, we aimed to assess if OSA is a risk factor for COVID-19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish residents with COVID-19 infection January 2020–May 202

Popular Abstract in English Proteins are a big biological molecules that help cells to function. Proteins play important roles in all vital processes of the living cell, transporting molecules, speeding up chemical reactions, supporting structure of other proteins and the cell, helping the cell to move. Various disease-causing agents (e.g. bacteria and viruses) are constant threat to us. It is thMost drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca

As energy demand increases worldwide, the interest in hydrogen has increased as well. Hydrogen is an excellent energy source and an essential component in large industries such as oil refineries, ammonia production plants and methanol synthesis plants. To produce hydrogen, steam methane reforming process is used where methane (CH4) and steam (H2O) is converted to carbon monoxide (CO) and hydrogen

With an increasing amount of literature on the convergence of archives and libraries as a point of departure, this thesis examines how archives and libraries respectively assign metadata to informational resources with queer content. Thereby, the thesis contribute to a theoretical convergence between the two institutions. A mixed method approach with quantitative and qualitative methods was chos

ABSTRACT Background: In the growing body of knowledge on how human environment impacts population health, the transport sector is observed to occupy strategic position. However, the transport corridors equally serve as sources of socio-economic challenges. Such is the case of the transport sector’s contribution to the HIV/AIDS epidemic. In this respect, truckers are observed to carry a disproporti

The area of direct taxation is, as a consequence of the limited harmonisation within the EU, an area surrounded by several interests that have appeared to be hard to unite. On one hand the EU Member States have the competence in the area of direct taxation to legislate in conformity with their own political considerations. On the other hand the EU law demands conformity with the freedoms regulated

SynopsisProtonolysis of the title compounds involves rate-determining proton transfer to the substrate. Subsequent isomerization is dissociative. Activation volumes for the two processes have opposite signs. A new kinetic β-hydrogen accelerating effect for isomerization favoring the fluxionality of a T-shaped 14-electron intermediate is reported.AbstractProtonolysis of the complexes cis-[PtR2(PEt3

Synchrotron radiation sources have greatly contributed to the progress in many fields of science. The development of the storage ring technologies have made possible to obtain very low emittance electron beams, which together with the use of undulators allow to guide a very high photon flux into a very small beam size required by the experiments. Development of sources has been accompanied with eq

Background: According to the “brain-reserve hypothesis” in Alzheimer’s disease (AD), patients with more years of education are expected to have higher cognitive status during adulthood. Hence, they might have a relatively larger burden of AD pathology and a more advanced level of the disease when dementia is clinically evident. Higher educated people would also be expected to perform better on sta

HILMA HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 27, 2001/02, Nr 9, 2002 05 07 SEMINARIER & UNDERVISNING Se det Gröna schemat. De närmast kommande seminarierna är 8/5 Sara Edenheim: Seminariet inställt t v. 21/5 Mikael Tossavainen: A Theoretical Practice or a Practical Theory. Klas-Göran Karlsson. 23/5 Jan Selling: Seminariet flyttat till september. 30/5 Joachim Östlund: Från furst

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_vt02_9_03.pdf - 2026-05-25

Rationale: Regular, low-dose, sustained-release morphine is frequently prescribed for persistent breathlessness in chronic obstructive pulmonary disease (COPD). However, effects on daytime sleepiness, perceived sleep quality, and daytime function have not been rigorously investigated. Objectives: We sought to determine the effects of regular, low-dose, sustained-release morphine on sleep parameter

There are no known estimates of the prevalence, severity and impacts from breathlessness in low- and middle-income countries. This study aimed to explore the prevalence, severity, self-attributed underlying conditions and impacts of breathlessness limiting exertion in community-dwelling adults in India. This exploratory, population-based online survey recruited a pre-planned sample of 3,000 adult

Servicearbetets förvandlingar och förhandlingar Inst för servIce management och tjänstevetenskap erIka andersson cederholm & carIna sjöholm (red.) redaktörer Erika Andersson Cederholm, erika.andersson_cederholm@ism.lu.se Carina Sjöholm, carina.sjoholm@ism.lu.se © Författarna 2014 lunds unIversItet Institutionen för service management och tjänstevetenskap Universitetsplatsen 2 Box 882, 251 08 Helsi

https://www.ses.lu.se/sites/ses.lu.se/files/servicearbetetwebb5.pdf - 2026-05-27

Background: We aimed to evaluate cumulative occurrence and impact of COVID-19 in patients with chronic respiratory failure (CRF) treated with long-term oxygen therapy (LTOT). Material and methods: Data were obtained from the SCIFI-PEARL study on the entire Swedish population and on patients with oxygen-dependent CRF and no COVID-19 diagnosis before start of LTOT. Analyses were performed for three

Progressive pulmonary fibrosis (PF) is a complex interstitial lung disease that impacts substantially on patients’ daily lives, requiring personalised and integrated care. We summarise the main needs of patients with PF and their caregivers, and suggest a supportive care approach. Individualised care, education, emotional and psychological support, specialised treatments, and better access to info

Purpose of Review: Many aspects of reproduction have been associated with increased blood pressure and impaired glucose metabolism that reveals a subsequent increased risk of cardiovascular disease. The aim of this review is to assess reproductive life factors associated with an increased risk of hypertension and cardiovascular disease, e.g., early life programming, sexual, and reproductive health