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Associations between autoimmune conditions and hepatobiliary cancer risk among elderly US adults
Growing evidence suggests that people with autoimmune conditions may be at increased risk of hepatobiliary tumors. In the present study, we evaluated associations between autoimmune conditions and hepatobiliary cancers among adults aged ≥66 in the United States. We used Surveillance, Epidemiology, and End Results (SEER)-Medicare data (1992–2013) to conduct a population-based, case–control study. C
Estimation of HIV incidence and its trend in three key populations in Iran
In Iran, People Who Inject Drugs (PWID), Female Sex Workers (FSW), and prisoners are the main key populations at risk of HIV infection. This study aimed to evaluate the trend of HIV incidence among PWID, FSW and prisoners as an impact measure of HIV harm reduction and prevention efforts in Iran. Data were obtained from the two rounds of national bio-behavioral surveillance surveys among FSW (2010
Nanowire photodetectors with embedded quantum heterostructures for infrared detection
Nanowires offer remarkable opportunities for realizing new optoelectronic devices because of their unique fundamental properties. The ability to engineer nanowire heterostructures with large bandgap variations is particularly interesting for technologically important broadband photodetector applications. Here we report on infrared photodetectors based on arrays of InP nanowires with embedded InAsP
Blood glucose and hypertension development : the hen and egg controversy
Thrombocytopenia in bacteraemia and association with bacterial species
Thrombocytopenia is common in patients with invasive bacterial infections. Bacteria can activate platelets, but it is unclear if this affects platelet count. The aim of this study was to examine whether bacteraemia with Staphylococcus aureus, which readily activate human platelets, was more likely to be complicated by thrombocytopenia than bacteraemia with Escherichia coli or Streptococcus pneumon
Associations of cigarette smoking with disease phenotype and type I interferon expression in primary Sjögren's syndrome
Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patients filled out the EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI) form
Factor V-short and protein S as synergistic tissue factor pathway inhibitor (TFPIα) cofactors
A method for selective etching of nanostructures
The ELI-ALPS secondary sources : A getaway to scientific excellence
The essence of ELI-ALPS, the laser driven secondary sources ranging from X-ray and X-UV to THz with duration as short as tens of attoseconds, are designed to be available for users from 2016.
Starch hydrolysis products with physiological activity in humans
Starch has undisputable importance in foods both from the nutritional—mainly energy—related‐and technological viewpoints. Different types of starch derivatives, including a number of hydrolysis products, are frequently used as food ingredients, especially because of the particular physicochemical properties they may confer. In recent years, certain hydrolytic derivatives of starch, such as maltode
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
Genome-wide association studies (GWAS) have advanced our understanding of susceptibility to B-cell precursor acute lymphoblastic leukemia (BCP-ALL); however, much of the heritable risk remains unidentified. Here, we perform a GWAS and conduct a meta-analysis with two existing GWAS, totaling 2442 cases and 14,609 controls. We identify risk loci for BCP-ALL at 8q24.21 (rs28665337, P = 3.86 × 10-9, o
Single-Mode Near-Infrared Lasing in a GaAsSb-Based Nanowire Superlattice at Room Temperature
Semiconductor nanowire lasers can produce guided coherent light emission with miniaturized geometry, bringing about new possibilities for a variety of applications including nanophotonic circuits, optical sensing, and on-chip and chip-to-chip optical communications. Here, we report on the realization of single-mode and room-temperature lasing from 890 to 990 nm, utilizing a novel design of single
Nanostructures for Optoelectronics : Device Fabrication and Characterization
The nanoscale is an exciting domain when it comes to crystal growth, light-matter interaction and electronics. Especially for optoelectronics, semiconductor nanostructures have many advantages compared to traditional planar structures and are highly interesting for the next generation of solar cells, photodetectors and light emitting diodes. This dissertation explores device fabrication, and elect
Prognostic impact of systolic blood pressure variability in people with diabetes
Objective Blood pressure variability (BPV) has been associated with risk of cardiovascular events in observational studies, independently of mean BP levels. In states with higher autonomic imbalance, such as in diabetes, the importance of BP variability may theoretically be even greater. We aimed to investigate the incremental value of BPV for prediction of cardiovascular and all-cause mortality i
Correct interpretation of nanofluid convective heat transfer
Engineers and scientist have a long tradition in trying to improve the thermophysical properties of convective heat carriers such as water and transformer oil. Technological developments of the last decades allow the dispersion of particle of sizes ranging between 10 and 100 nm in these liquids. In a large number of recent studies the resulting nanofluids have been reported to display anomalously
Nanoimprint stamps with ultra-high resolution : Optimal fabrication techniques
Single-digit nanometer patterning by nanoimprint lithography is a challenging task, which requires optimum stamp fabrication technique. In the current work, we present different strategies for technology of hard master stamps to make intermediate working stamps with sub-10 nm features. Methods of both negative and positive master stamps fabrication, based on EBL, RIE and ALD are described and comp
Strong spin-orbit interaction and magnetotransport in semiconductor Bi2O2Se nanoplates
Semiconductor Bi2O2Se nanolayers of high crystal quality have been realized via epitaxial growth. These two-dimensional (2D) materials possess excellent electron transport properties with potential application in nanoelectronics. It is also strongly expected that the 2D Bi2O2Se nanolayers can be an excellent material platform for developing spintronic and topological quantum devices if the presenc
Nanoscale electron tomography and compositional analysis of Aerotaxy nanowires
One common goal of sample analysis is to provide structural, compositional, or functional data in order to improve production parameters. One instrument specialized in such structural and compositional analysis with a high spatial resolution is the transmission electron microscope (TEM). The high-end microscopes have the capability of sub-Ångström resolution and compositional quantification and di
Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer
Constitutive activation of interferon signaling pathways has been reported in colorectal cancer (CRC), leading to a strong CD8+ T cell response through stimulation of NLRC5 expression. Primed CD8+ T cell expansion, however, may be negatively regulated by PD-L1 expression. Additionally, aberrant PD-L1 expression enables cancer cells to escape the immune attack. Our study aimed to select potential r
