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Maternal plasma leptin levels in relation to the duration of the active phase of labor

Introduction: Obese women have increased leptin levels and longer duration of labor compared with normal-weight women. Leptin has an inhibitory effect on myometrial contractility in vitro. Our purpose was to examine whether maternal leptin levels in active labor were associated with the duration of the active phase of labor. Material and methods: This prospective cohort study included 914 women. M

Genetic Variants Associated with Circulating Fibroblast Growth Factor 23

BACKGROUND: Fibroblast growth factor 23 (FGF23), a bone-derived hormone that regulates phosphorus and vitamin D metabolism, contributes to the pathogenesis of mineral and bone disorders in CKD and is an emerging cardiovascular risk factor. Central elements of FGF23 regulation remain incompletely understood; genetic variation may help explain interindividual differences.METHODS: We performed a meta

International Society of Blood Transfusion Working Party on Red Cell Immunogenetics and Blood Group Terminology : Report of the Dubai, Copenhagen and Toronto meetings

Background and objectives: The International Society of Blood Transfusion (ISBT) Working Party for Red Cell Immunogenetics and Blood Group Terminology meets in association with the ISBT congress and has met three times since the last report: at the international meetings held in Dubai, United Arab Emirates, September 2016 and Toronto, Canada, June 2018; and at a regional congress in Copenhagen, De

Investigation of mixed convection in an enclosure filled with nanofluids of Al2O3 –water and graphene-ethylene glycol

In this research work, heat transfer enhancement of mixed convection in an enclosure is investigated with a moving top wall. Numerical simulations based on an Al2 O3 –water nanofluid are conducted by using variable thermophysical properties. Flow fields and temperature distributions are analyzed by considering effects of two partially heated walls. Moreover, water–ethylene glycol mixed with graphe

Unravelling uniaxial strain effects on electronic correlations, hybridization and bonding in transition metal oxides

The interplay among spin, lattice, charge and orbit is of central importance for several rich and fascinating properties of oxides, and is the subject of intense research at present. Here, we present an approach to manipulate this interplay by Sn doping to effectively apply uniaxial strain on the TiO2 lattice. The evolution of this interplay in pseudo-homoepitaxial Ti1-xSnxO2 films is measured usi

Up to speed : Birth cohort effects observed for speed of processing in older adults: Data from the Good Ageing in Skåne population study

Neuropsychological test-based norms are vital for accurate assessment of older adults’ level of cognition. Hence, it is important that these scores are not conflated with birth cohort effects. With data drawn from the Swedish Good Ageing in Skåne (GÅS) population study, this study examined birth cohort effects on test scores measuring several cognitive domains. A time-lag design with three distinc

Physical activity may compensate for prolonged TV time regarding pulse rate—a cross-sectional study

Background. Regular exercise reduces pulse rate, but it is less clear how prolonged sitting time affects pulse rate. Our hypothesis was that high physical activity could compensate for prolonged sitting time regarding the pulse rate. Methods. Regression analysis was performed on cross-sectional data including 47,457 men and women based on two Swedish cohort studies, EpiHealth (18–45 years) and Lif

Evaluation of quality of care in relation to health-related quality of life of patients diagnosed with brain tumor : a novel clinic for proton beam therapy

Purpose: Patients with brain tumors constitute a vulnerable group, and it is important that they receive the highest quality of care (QoC). The study aim was to describe the perceptions of QoC and its association with health-related quality of life in brain tumor patients undergoing proton beam therapy in a newly established clinic. Method: Data were collected at the start of treatment and after 3

Variations in the vitamin D receptor gene are not associated with measures of muscle strength, physical performance, or falls in elderly men. Data from MrOS Sweden

The vitamin D receptor (VDR) has been proposed as a candidate gene for several musculoskeletal phenotypes. However, previous results on the associations between genetic variants of the VDR with muscle strength and falls have been contradictory. The MrOS Sweden survey, a prospective population-based cohort study of 3014 elderly men (mean age 75 years, range 69–81) offered the opportunity to further

A simple multilevel approach for analysing geographical inequalities in public health reports: : The case of municipality differences in obesity

The epidemiological analysis of geographical inequalities in individual outcomes is a fundamental theme in public health research. However, many traditional studies focus on analysing area differences in averages outcomes, disregarding individual variation around such averages. In doing so, these studies may produce misleading information and lead researchers to draw incorrect conclusions. Analysi

Occupational exposure to organic particles and combustion products during pregnancy and birth outcome in a nationwide cohort study in Sweden

Objective: To study if children of women exposed to organic particles and combustion products at work during pregnancy, have an increased risk of low birth weight, preterm birth or small for gestational age. Methods: A nationwide cohort of all occupationally active mothers and their children from single births during 1994 to the end of 2012 (1 182 138 observations) was formed. Information on birth

Compact, few-cycle OPCPA system with ultralow CEP noise

A compact, high-repetition rate OPCPA system with CEP-stable 6.3 fs pulses duration and 10 μJ of pulse energy is presented together with results from numerical simulations. First results of high harmonic generation will be shown.

Idrottande barn och ung­domar »vaccineras« mot frakturer i vuxenlivet : Träning är bra för alla – på olika sätt

High mechanical load in alternating directions with sufficient rest in between the loading periods is one of the best stimuli to enhance bone mass and skeletal structure, both contributing independently to bone strength. The age-frame where skeletal benefits from exercise are largest is in late pre- and early peri-puberty. Recent publications with low level of evidence infer that such skeletal ben

Fluoroquinolone use and risk of aortic aneurysm and dissection : Nationwide cohort study

Objective To investigate whether oral fluoroquinolone use is associated with an increased risk of aortic aneurysm or dissection. Design Nationwide historical cohort study using linked register data on patient characteristics, filled prescriptions, and cases of aortic aneurysm or dissection. Setting Sweden, July 2006 to December 2013. Participants 360 088 treatment episodes of fluoroquinolone use (

Hormonal contraception increases the risk of psychotropic drug use in adolescent girls but not in adults : A pharmacoepidemiological study on 800 000 Swedish women

The burden of depression and anxiety disorders is greater in women, and female sex hormones have been shown to affect mood. Psychological side effects of hormonal contraception (HC) are also a common complaint in the clinic, but few previous studies have investigated this subject. We therefore wanted to investigate whether use of HC was associated with adverse psychological health outcomes, and wh

Serotype distribution of clinical streptococcus pneumoniae isolates before the introduction of the 13-valent pneumococcal conjugate vaccine in Cambodia

Childhood vaccination with the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in Cambodia in January 2015. Baseline data regarding circulating serotypes are scarce. All microbiology laboratories in Cambodia were contacted for identification of stored isolates of Streptococcus pneumoniae from clinical specimens taken before the introduction of PCV13. Available isolates were serotyp

Quantum memory development and new slow light applications in rare-earth-ion-doped crystals

When doped into solid state transparent crystals, rare-earth ions can have optically excited states with milliseconds coherence time and up to six hours coherence time for hyperfine levels after being cooled down to liquid helium temperature. This long coherence property makes them unique as solid state material and attractive for quantum information applications.The rare-earth ions have narrow ho

Interaction between physical activity and television time on blood pressure level : Cross-sectional data from 45 000 individuals

Objectives: The aim was to investigate if there is an interaction between sitting time and leisure time physical activity on blood pressure and if there are age differences and sex differences in this respect. Methods: Linear regression analysis on cross-sectional data was performed in more than 45 000 men and women from two Swedish cohort studies, EpiHealth (45-75 years) and LifeGene (18-45 years