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Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value 1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were i
Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor, platelet-derived growth factor receptor, and fibroblast growth factor receptor, has shown activity in phase 2 trials in this setting. We investigated the combination of nintedanib with standard carboplatin and paclitaxel chemotherapy in patients with newly diagnosed advan
The immune system has evolved specialized cellular and molecular mechanisms for targeting and regulating immune responses at epithelial surfaces. Here we show that small intestinal intraepithelial lymphocytes and lamina propria lymphocytes migrate to thymus-expressed chemokine (TECK). This attraction is mediated by CC chemokine receptor (CCR)9, a chemoattractant receptor expressed at high levels b
TECK (thymus-expressed chemokine), a recently described CC chemokine expressed in thymus and small intestine, was found to mediate chemotaxis of human G protein-coupled receptor GPR-9-6/L1.2 transfectants. This activity was blocked by anti-GPR-9-6 monoclonal antibody (mAb) 3C3. GPR-9-6 is expressed on a subset of memory alpha4beta7(high) intestinal trafficking CD4 and CD8 lymphocytes. In addition,
Ancient Italic terracottas were painted before or after firing depending on their function, as suggested by previous analyses. However, concerning the votive terracottas, there seems to have been no anlayses carried out, suggesting either a fired or non fired paint. Methods and problems associated with an ongoing research on some votive terracottas from Tessennano in Southern Etruria are considere
RWI 2024 Annual Report ANNUAL REPORT 2024 ADVANCING HUMAN RIGHTS AND HUMANITARIAN LAW STRENGTHENING ACCOUNTABILITY AND JUSTICE DRIVING POSITIVE CHANGE As we usher in the 41st year of operation at the Raoul Wallenberg Institute (RWI), I am honored to present this 2024 Annual Report as a reflection of what we accomplished throughout 2024 as well as the values and direction that will guide us as we c
https://rwi.lu.se/wp-content/uploads/2025/06/RWI-2024-Annual-Report.pdf - 2026-05-07
Reducing global emissions will require a global cosmopolitan culture built from detailed attention to conflicting national climate change frames (interpretations) in media discourse. The authors analyze the global field of media climate change discourse using 17 diverse cases and 131 frames. They find four main conflicting dimensions of difference: validity of climate science, scale of ecological
Introduction: Planning cranioplasty (CPL) in patients with suspected or proven post-traumatic hydrocephalus (PTH) poses a significant management challenge due to a lack of clear guidance. Research question: This project aims to create a European document to improve adherence and adapt to local protocols based on available resources and national health systems. Methods: After a thorough non-systema
We review the main software and computing challenges for the Monte Carlo physics event generators used by the LHC experiments, in view of the High-Luminosity LHC (HL-LHC) physics programme. This paper has been prepared by the HEP Software Foundation (HSF) Physics Event Generator Working Group as an input to the LHCC review of HL-LHC computing, which has started in May 2020.
Driven by co-evolution with pathogens, host immunity continuously adapts to optimize defence against pathogens within a given environment. Recent advances in genetics, genomics and transcriptomics have enabled a more detailed investigation into how immunogenetic variation shapes the diversity of immune responses seen across domestic and wild animal species. However, a deeper understanding of the d
BACKGROUND/PURPOSE: Non-resuscitation fluids constitute the majority of fluid administered for septic shock patients in the intensive care unit (ICU). This multicentre, randomized, feasibility trial was conducted to test the hypothesis that a restrictive protocol targeting non-resuscitation fluids reduces the overall volume administered compared with usual care.METHODS: Adults with septic shock in
In septic shock, administration of large fluid volumes is associated with poor outcomes. Recent evidence shows that non-resuscitation fluids are the major modifiable source of fluids for patients with septic shock in intensive care units (ICUs). This clinical trial is designed to test the hypothesis that restrictive administration of non-resuscitation fluids improves outcomes compared to usual car
Background: Basic management for patients who have suffered a cardiac arrest and are admitted to an intensive care unit (ICU) after resuscitation includes setting targets for blood pressure and managing sedation and temperature. However, optimal targets and management are unknown. Methods: The STEPCARE (Sedation, Temperature and Pressure after Cardiac Arrest and Resuscitation) trial is a multicent
Purpose: Application of standardised and automated assessments of head computed tomography (CT) for neuroprognostication after out-of-hospital cardiac arrest. Methods: Prospective, international, multicentre, observational study within the Targeted Hypothermia versus Targeted Normothermia after out-of-hospital cardiac arrest (TTM2) trial. Routine CTs from adult unconscious patients obtained > 48 h
Background When the lectinlike oxidized low-density lipoprotein (ox LDL) receptor-1 ( LOX -1), a scavenger receptor for ox LDL , binds ox LDL , processes leading to endothelial dysfunction and inflammation are promoted. We aimed to study release mechanisms of LOX -1 and how circulating levels of soluble LOX -1 ( sLOX -1) relate to plaque inflammation and future risk for ischemic stroke. Methods an
Gene panel sequencing has become a common diagnostic tool for detecting somatically acquired mutations in myeloid neoplasms. However, many panels have restricted content, provide insufficient sensitivity levels, or lack clinically validated workflows. We here describe the development and validation of the Genomic Medicine Sweden myeloid gene panel (GMS-MGP), a capture-based 191 gene panel includin
Brevmall Postadress Box 117, 221 00 LUND Besöksadress Sölvegatan 14 A, LUND Telefon dir 046-222 4403, växel 046-222 00 00 Fax 046-222 4410 E-post isabella.grujoska@kansliht.lu.se Webbadress http://www.ht.lu.se Fakul te tss tyre lsen Humanistiska och teologiska fakulteternas plan för jämställdhet, likabehandling och mångfald 2014 Förutsättningar Arbetet med jämställdhet, likabehandling och mångfald
https://www.ctr.lu.se/fileadmin/user_upload/ctr/pdf/policy/JLM-plan_2014_BESLUT.pdf - 2026-05-07
Saco-S föreningen i Specialpedagogiska skolmyndigheten 1 Verksamhetsberättelse 2025 för Saco-S föreningen i Specialpedagogiska skolmyndigheten Verksamhet under tiden 1 januari 2025 till 31 december 2025 Saco-S föreningen i Specialpedagogiska skolmyndigheten 2 Innehållsförteckning Styrelse under 2025 ...................................................................................................
https://www.saco.se/contentassets/9ffcb08ee87844a5af2ed9fc6e2afd74/saco-s-verksamhetsberattelse-for-2025.pdf - 2026-05-08
Svenskt Näringsliv - PTK Omställningsavtal 1998– 01– 01 Svenskt Näringsliv bildades den 29 mars 2001 genom en ombildning av SAF som ursprungligen var part i avtalet. Förhandlings- och samverkansrådet PTK bildades den 13 december 2004 genom en organisationsförändring av Privattjänste- mannakartellen som ursprungligen var part i avtalet. SvNarLivPTKOmstallningsavt.qxp 06-10-10 09.47 Sida 1 SvNarLivP
