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The molecular pathogenesis of collagen-induced arthritis in mice--a model for rheumatoid arthritis.

The most widely used model for rheumatoid arthritis is the collagen-induced arthritis (CIA) in mice. This model has gained acceptance since it is reproducible, well defined and has proven useful for development of new therapies for rheumatoid arthritis, as exemplified by the most recent advancement using TNFalpha neutralization treatment. The collagen-induced arthritis model, however, represents o

Abnormal melatonin synthesis in autism spectrum disorders

Melatonin is produced in the dark by the pineal gland and is a key regulator of circadian and seasonal rhythms. A low melatonin level was reported in individuals with autism spectrum disorders (ASD), but the underlying cause of this deficit was unknown. The ASMT gene, encoding the last enzyme of melatonin synthesis, is located on the pseudo-autosomal region 1 of the sex chromosomes, deleted in sev

Sublytic Activity of a Pore-Forming Protein From Commensal Bacteria Causes Epigenetic Modulation of Tumour-Affiliated Protein Expression

Cytolysin A (ClyA) is a pore-forming protein from a strongly silenced gene in non-pathogenic Escherichia coli, including typical commensal isolates in the intestinal microbiome of healthy mammalian hosts. Upon overproduction, ClyA-expressing bacteria display a cytolytic phenotype. However, it remains unclear whether sublytic amounts of native ClyA play a role in commensal E. coli-host interactions

Classifying a distinct form of diabetes in lean individuals with a history of undernutrition : an international consensus statement

Since 1955, a form of diabetes in lean, young (BMI <18·5 kg/m2, age <30 years) individuals with a history suggestive of undernutrition from before birth and throughout childhood has been described in the literature. In 1985, WHO formally classified it as malnutrition-related diabetes, but subsequently removed the classification in 1999 over a disagreement as to whether undernutrition was a suffici

edge: the emergence of dwarf galaxy scaling relations from cosmological radiation-hydrodynamics simulations

We present a new suite of edge ('Engineering Dwarfs at Galaxy formation's Edge') cosmological zoom simulations. The suite includes 15 radiation-hydrodynamical dwarf galaxies covering the ultrafaint to the dwarf irregular regime () to enable comparisons with observed scaling relations. Each object in the suite is evolved at high resolution () and includes stellar radiation, winds, and supernova fee

Impact of Dapagliflozin on Cardiometabolic Outcomes After Acute Myocardial Infarction According to Baseline Glycemic Status and Body Mass Index : Subanalyses of the DAPA-MI Trial

BACKGROUND: Dapagliflozin improved cardiometabolic outcomes following myocardial infarction in patients without prior type-2 diabetes (T2DM) in the DAPA-MI (dapagliflozin in patients with myocardial infarction) trial. The effect of glycemic status and body mass index (BMI) post–myocardial infarction requires elucidation. METHODS: Participants with T2DM diagnosis, without baseline hemoglobin A1c, o

An extraordinary, ordinary day

An extraordinary, ordinary day Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any perso

https://www.lth.se/english/article/an-extraordinary-ordinary-day/ - 2026-05-09

Information for new employees

Information for new employees | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These c

https://www.lth.se/english/work/information-for-new-employees/ - 2026-05-09

Call for Applications of Researchers in Southern Africa - The Raoul Wallenberg Institute of Human Ri

Call for Applications of Researchers in Southern Africa - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreac

https://rwi.lu.se/news/call-for-applications-of-researchers-in-southern-africa/ - 2026-05-09

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Concept Note “Human Rights Research in Armenia: Current and Emerging Issues” 4th International Conference organised by the Raoul Wallenberg Institute of Human Rights and Humanitarian Law, in Yerevan, November 13-14, 2026 The Raoul Wallenberg Institute of Human Rights and Humanitarian Law (hereinafter “RWI”), Lund, Sweden is pleased to announce the fourth international conference "Human Rights Rese

https://rwi.lu.se/wp-content/uploads/2026/04/Concept-Note-for-the-Conference-_RWI_2026_EN.docx - 2026-05-09

Fever management with or without a temperature control device after out-of-hospital cardiac arrest and resuscitation (TEMP-CARE): A study protocol for a randomized clinical trial

BACKGROUND: Fever is associated with brain injury after cardiac arrest. It is unknown whether fever management with a feedback-controlled device impacts patient-centered outcomes in cardiac arrest patients. This trial aims to investigate fever management with or without a temperature control device after out-of-hospital cardiac arrest. METHODS: The TEMP-CARE trial is part of the 2 × 2 × 2 factoria

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

Genetic studies promise to provide insight into the molecular mechanisms underlying type 2 diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer clusters or super-enhancers. So far, such domains have been defined through clustering of enhancers in linear genome maps rather than in three-dimensional (3D) space. Furthermore, their target genes are often unknown.

Performance of b-jet identification in the ATLAS experiment

The identification of jets containing b hadrons is important for the physics programme of the ATLAS experiment at the Large Hadron Collider. Several algorithms to identify jets containing b hadrons are described, ranging from those based on the reconstruction of an inclusive secondary vertex or the presence of tracks with large impact parameters to combined tagging algorithms making use of multi-v

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untitled LETTERS New flutes document the earliest musical tradition in southwestern Germany Nicholas J. Conard1, Maria Malina2 & Susanne C. Münzel3 Considerable debate surrounds claims for early evidence of music in the archaeological record1–5. Researchers universally accept the existence of complex musical instruments as an indication of fully modern behaviour and advanced symbolic communicatio

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/Conard_et_al._Flutes_Nature_2009.pdf - 2026-05-09

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Kurskommentar Analytiska funktioner ht 2020 Anders Olofsson Resultatet p̊a kursen är 13 stycken G och 24 stycken VG fördelat p̊a tv̊a stycken tentamenstillfällen. Kursvärderingarna var genomg̊aende positiva, se r̊adata för detaljer. Genomförandet av kursen stördes av korona-utbrottet 2020. Pga r̊adande restrik- tioner ersattes salstentamen med examination i form av skriftlig hemtentamen. Pg

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2020/MATM12HT2020KA.pdf - 2026-05-09

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Centre for Mathemat ica l Sc iences Divis ion of Mathemat ics and Numerica l Analys is Course Analysis for MATB22 Linear Algebra 2, Spring 2024 Course Information Lecturer: Anitha Thillaisundaram Teaching assistants: Jan Henrik Thomm and Thomas Munn Number of students: 44 newly registered and 21 re-registered. 14 students answered the course evaluation, all of them are enrolled on programme name.

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2024/MATB22VT24.pdf - 2026-05-09

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VI International Conference on Computational Methods for Coupled Problems in Science and Engineering COUPLED PROBLEMS 2015 B. Schrefler, E. Oñate and M. Papadrakakis(Eds) CONVERGENCE SPEED OF COUPLING ITERATIONS FOR THE UNSTEADY TRANSMISSION PROBLEM AZAHAR MONGE∗ AND PHILIPP BIRKEN∗ ∗Centre for Mathematical Sciences Lund University Box 118, 22100, Lund, Sweden e-mail: azahar.monge@na.lu.se, web p

https://www.maths.lu.se/fileadmin/maths/personal_staff/Philipp_Birken/coupled.pdf - 2026-05-10