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Abstract A novel set of integrated procedures for quantification of fibroblast-rich stroma and vascular characteristics has recently been presented allowing discovery of novel perivascular and stromal biomarkers in colorectal, renal cell, and ovarian cancer. In the present study, data obtained through these procedures from clinically well-annotated collections of these three tumour types have been

OBJECTIVES: We assessed pharmacodynamic (PD) response for the reduced prasugrel 5-mg maintenance dose in very elderly (≥75y; VE) patients. BACKGROUND: In TRITON-TIMI 38, prasugrel 10-mg reduced ischemic events versus clopidogrel 75-mg, but increased bleeding in VE patients. METHODS: We examined PD and active-metabolite pharmacokinetics with prasugrel 5-mg and 10-mg and clopidogrel 75-mg in a three

Syndecan-2 is a heparan sulfate proteoglycan that has a cell adhesion regulatory domain contained within its extracellular core protein. Cell adhesion to the syndecan-2 extracellular domain (S2ED) is β1 integrin dependent; however, syndecan-2 is not an integrin ligand. Here the protein tyrosine phosphatase receptor CD148 is shown to be a key intermediary in cell adhesion to S2ED, with downstream β

Background: In the BRIGHT-4 (Bivalirudin With Prolonged Full-Dose Infusion During Primary PCI Versus Heparin Trial-4), anticoagulation with bivalirudin plus a 2- to 4-hour high-dose infusion after percutaneous coronary intervention (PCI) reduced all-cause mortality and bleeding without increasing reinfarction or stent thrombosis compared with heparin alone in patients with ST-segment elevation myo

Myxofibrosarcoma (MFS) and undifferentiated pleomorphic sarcoma (UPS) are two common and aggressive subtypes of soft tissue sarcoma. The aim of this study was to assess potential transcriptomic differences between MFS and UPS tumours and to evaluate the extent to which differences in gene expression profiles were associated with genomic and clinical features. The study included 162 patients with t

Background: Persistent non-plateauing adverse event rates in patients who underwent percutaneous coronary intervention (PCI) remain a challenge. A bioadaptor is a novel implant that addresses this issue by restoring the haemodynamic modulation of the artery, allowing cyclic pulsatility, vasomotion, and adaptative remodelling, by unlocking and providing dynamic support to the artery. We aimed to as

Polarized fluorescence microscopy is a valuable tool for measuring molecular orientations in biological samples, but techniques for recovering three-dimensional orientations and positions of fluorescent ensembles are limited. We report a polarized dual-view light-sheet system for determining the diffraction-limited three-dimensional distribution of the orientations and positions of ensembles of fl

Background: Vasovagal syncope (VVS) is a common yet challenging condition with limited effective treatments. Elastic compression stockings (ECS) have been proposed as a potential therapy, but their real-world effectiveness remains unclear. Objectives: This study sought to compare the effectiveness of lower extremity compression with thigh-high ECS vs sham stockings for the prevention of VVS recurr

I denna uppsats undersöks skälen till och rättfärdigandet av att hela kon-cerner hålls ansvariga för överträdelser av EU:s konkurrensrätt i stället för de företag inom koncernen som aktivt deltagit i överträdelsen. I uppsatsen undersöks presumtionen om att moderbolag utövar ett avgörande infly-tande, en rättslig mekanism som innebär att ett moderbolag tillskrivs an-svar utan att några ytterligare This thesis examines the rationale and justification of imputing liability for infringements of EU competition law to entire corporate groups rather than on the legal entities within that group that actively participated in the infringement. It explores the presumption of decisive influence, a legal mechanism which attributes liability on a parent company without adduc-ing any further evidence of

WD 1145+017 is currently the only white dwarf known to exhibit periodic transits of planetary debris as well as absorption lines from circumstellar gas. We present the first simultaneous fast optical spectrophotometry and broad-band photometry of the system, obtained with the Gran Telescopio Canarias (GTC) and the Liverpool Telescope, respectively. The observations spanned 5.5 h, somewhat longer t

With this paper and the accompanying audio paper, our aim is to explore the juxtaposition of sound and democracy. Recognizing the multifaceted nature of this field, we approach it through the notion of care and an empirical analysis of democratic implications of trying to regulate sound in public spaces. We examine standards as one example of the many attempts to control sound in both public and p

Aktuellt om v&h leder 06 ny.indd 1 A K T U E L LT O M V E T E N S K A P O C H H Ä L S A • M A J 2 0 0 6 Kroppen i rörelse Maj 2006 Denna tidskrift ges ut av Medicinska fakulteten vid Lunds universitet och Universitetssjukhuset i Lund & Universitetssjukhuset MAS vid Region Skåne Aktuellt om VETENSKAP & HÄLSA 2 A K T U E L LT O M V E T E N S K A P O C H H Ä L S A • M A J 2 0 0 6 Aktuellt om VETENSKA

https://www.vetenskaphalsa.se/wp-content/uploads/2010/08/Aktuellt_om_vet_o_halsa_maj_06.pdf - 2026-05-11

LUNDS UNIVERSITET Sida 1 av 6 HUMANISTISKA OCH TEOLOGISKA FAKULTETERNA PROTOKOLL Diarienummer STYR 2024/442 Sammanträdesdatum 2024-04-05, kl. 09.00-12.00 Grundutbildnings nämnden Grundutbildningsnämndens sammanträde 2024-04-05 Ledamöter Närvarande Sara Håkansson, universitetslektor, prodekan/ordförande David Alm, universitetslektor Nils Breding, student Tess Fredriksson, student Patrik Fridlund, u

https://www.ht.lu.se/fileadmin/user_upload/ht/Protokoll_GUN_2024.pdf - 2026-05-11

REPORT TITLE 1 Alaba Ibironke Kekere & Victoria Banke Olagbegi-Oloba SAFEGUARDING THE RIGHTS OF WOMEN AND FEMALE CHILDREN UNDER THE CUSTOMARY LAW OF INHERITANCE: ISSUES AND CHALLENGES IN NIGERIA AND SOUTH AFRICA 0 The views and opinions expressed in this research are those of the authors and do not necessarily reflect the views of either RWI or Sida. Supported by The Swedish International Developm

https://rwi.lu.se/wp-content/uploads/2025/06/Kekere-and-Obola.pdf - 2026-05-11

Utbildningsplan Masterprogram i litteratur - kultur - medier Humanistiska och teologiska fakulteterna HALKM, Masterprogram i litteratur - kultur - medier, 120 högskolepoäng Master's Programme in Literature - Culture - Media, 120 credits Program med akademiska förkunskapskrav och med slutlig examen på avancerad nivå / Second cycle degree programme requiring previous university study Beslutsuppgifte

https://www.sol.lu.se/fileadmin/user_upload/sol/utbildning/Utbildningsplaner/Utbildningsplan_Masterprogram_i_litteratur_-_kultur_-_medier.pdf - 2026-05-11

Background—Mechanical chest compression (CC) is currently suggested to deliver sustained high-quality CC in a moving ambulance. This study compared the hemodynamic support provided by a mechanical piston device or manual CC during ambulance transport in a porcine model of cardiopulmonary resuscitation. Methods and Results—In a simulated urban ambulance transport, 16 pigs in cardiac arrest were ra

The processes that led to the formation of the planetary bodies in the Solar system are still not fully understood. Using the results obtained with the comprehensive suite of instruments onboard the European Space Agency's Rosetta mission, we present evidence that comet 67P/Churyumov-Gerasimenko likely formed through the gentle gravitational collapse of a bound clump of mm-sized dust aggregates ('

Chronic pruritus is a frequently occurring symptom of various dermatoses that causes a high burden and impaired quality of life. An effective anti pruritic therapy is important for the patient, but its effectiveness is difficult to evaluate. Diverse methods and interpretations of pruritic metrics are utilized in clinical trials and the daily clinical practice in different countries, resulting in d

In this thesis diet and health of people who lived in southern Sweden 2300-1100 BCE is studied. The study is based on bioarchaeological analyses of human remains from 46 localities in the areas of Uppland, Närke, Östergötland, Västergötland, and Scania. The studies are based on skeletal remains from a minimum number of 310 individuals that have been analysed both osteologically and biochemically.

We write with great concern in response to the recent systematic review and meta-analysis of cognitive-behavioral therapy (CBT) in pediatric obsessive-compulsive disorder (OCD) by Uhre et al.1 Although the authors’ results consistently support the clinical efficacy of CBT for pediatric OCD, we expect that, much like ourselves, readers will be confused by the discordant and inappropriate conclusion