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Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome

The gene IL6ST encodes GP130, the common signal transducer of the IL-6 cytokine family consisting of 10 cytokines. Previous studies have identified cytokine-selective IL6ST defects that preserve LIF signaling. We describe three unrelated families with at least five affected individuals who presented with lethal Stüve-Wiedemann-like syndrome characterized by skeletal dysplasia and neonatal lung dys

Genetic Variants Associated with Circulating Fibroblast Growth Factor 23

BACKGROUND: Fibroblast growth factor 23 (FGF23), a bone-derived hormone that regulates phosphorus and vitamin D metabolism, contributes to the pathogenesis of mineral and bone disorders in CKD and is an emerging cardiovascular risk factor. Central elements of FGF23 regulation remain incompletely understood; genetic variation may help explain interindividual differences.METHODS: We performed a meta

37 new validated planets in overlapping K2 campaigns

We analysed 68 candidate planetary systems first identified during Campaigns 5 and 6 (C5 and C6) of the NASA K2 mission. We set out to validate these systems by using a suite of follow-up observations, including adaptive optics, speckle imaging, and reconnaissance spectroscopy. The overlap between C5 with C16 and C18, and C6 with C17, yields light curves with long baselines that allow us to measur

Willingness among food consumers to recycle human urine as crop fertiliser : Evidence from a multinational survey

Source-separating sanitation systems offer the possibility of recycling nutrients present in wastewater as crop fertilisers. Thereby, they can reduce agriculture's impacts on global sources, sinks, and cycles for nitrogen and phosphorous, as well as their associated environmental costs. However, it has been broadly assumed that people would be reluctant to perform the new sanitation behaviours tha

Ibrutinib and rituximab versus immunochemotherapy in patients with previously untreated mantle cell lymphoma (ENRICH) : a randomised, open-label, phase 2/3 superiority trial

BackgroundIbrutinib, a Bruton tyrosine kinase inhibitor, prolongs progression-free survival when added to immunochemotherapy as first line treatment. The ENRICH trial compared the chemotherapy-free combination of ibrutinib and the anti-CD20 antibody rituximab (ibrutinib–rituximab) with standard immunochemotherapy (R-CHOP [rituximab–cyclophosphamide, doxorubicin, vincristine, and prednisolone] or b

Variation in human milk composition is related to differences in milk and infant fecal microbial communities

Previously published data from our group and others demonstrate that human milk oligosaccharide (HMOs), as well as milk and infant fecal microbial profiles, vary by geography. However, little is known about the geographical variation of other milk-borne factors, such as lactose and protein, as well as the associations among these factors and microbial community structures in milk and infant feces.

Rare variant, gene-based association study of hereditary melanoma using whole-exome sequencing

Background: Extraordinary progress has been made in our understanding of common variants in many diseases, including melanoma. Because the contribution of rare coding variants is not as well characterized, we performed an exome-wide, gene-based association study of familial cutaneous melanoma (CM) and ocular melanoma (OM). Methods: Using 11 990 jointly processed individual DNA samples, whole-exome

Class-switch recombination to IgA in the Peyer's patches requires natural thymus-derived Tregs and appears to be antigen independent

Our understanding of how class-switch recombination (CSR) to IgA occurs in the gut is still incomplete. Earlier studies have indicated that Tregs are important for IgA CSR and these cells were thought to transform into follicular helper T cells (Tfh), responsible for germinal center formation in the Peyer's patches (PP). Following adoptive transfer of T-cell receptor-transgenic (TCR-Tg) CD4 T cell

1025FR_A4_4d.pdf

1025FR_A4_4d.pdf Doctoral Thesis Structural Mechanics MARIA FRÖLING STRENGTH DESIGN METHODS FOR GLASS STRUCTURES DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS Copyright © Maria Fröling 2013. Printed by Media-Tryck LU, Lund, Sweden, September 2013 (Pl). For information, address: Division of Structural Mechanics, LTH, Lund University, Box 118, SE-221 00 Lund, Sweden. Homepage:

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm1000/web1025_utan_A1_o_A2_S5.pdf - 2026-05-14

Microsoft Word - Försättssidor2003-02-02.doc

Microsoft Word - Försättssidor2003-02-02.doc Doctoral Thesis Structural Mechanics TOMAS NORDSTRAND BASIC TESTING AND STRENGTH DESIGN OF CORRUGATED BOARD AND CONTAINERS Detta är en tom sida! Copyright © Tomas Nordstrand, 2003. Printed by KFS i Lund AB, Lund, Sweden, February 2003. For information, address: Division of Structural Mechanics, LTH, Lund University, Box 118, SE-221 00 Lund, Sweden. Home

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm1000/web1015.pdf - 2026-05-14

Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity

CONTEXT: Pancreatic beta-cell glucose sensitivity is the slope of the plasma glucose-insulin secretion relationship and is a key predictor of deteriorating glucose tolerance and development of type 2 diabetes. However, there are no large-scale studies looking at the genetic determinants of beta-cell glucose sensitivity. OBJECTIVE: To understand the genetic determinants of pancreatic beta-cell gluc

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Law Sociology Psychology Criminology Management Economics Gender Gender and law: first experience of teaching in Belarus Authors: Irina Kandrichina, Anastasiia Vorobiova, Alena Abramenka, Alina Bogolejko, Tatsiana Kisialiova, Natallia Ramazanava, Tatiana Telyatitskaya, Iryna Shakhnouskaya, Yuliia Prykolotina, Viktar Burakou, Olga Bezbozhna Translation from Russian: Translatio Agency (Minsk) Editin

https://rwi.lu.se/app/uploads/2020/08/updated-eng-version-belarus-pamplet.pdf - 2026-05-15

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Making sense of a “complete mess”: A study of reading comprehension in Danish Helle Lindsted Centre for Languages and Literature (SOL) Bachelor’s Thesis in Linguistics Supervisor: Tanja Kupisch Spring 2026 2 Abstract Various factors may impact the process of reading. The depth of the orthography influences the reading strategy for readers of shallow and deep orthographies because the complexity of

https://www.sol.lu.se/media/kalender/2026-05/Lindsted-kandidatuppsats.pdf - 2026-05-14

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165 Abstract The chapter reviews evidence for the bodily mimesis hypothesis, which states that the evolution of language was preceded by an adaptation for improved volitional control of the body, giving our ancestors advantages in the domains of imi- tation, empathy, and gestural communication. Much of this evidence is also shared by other gesture-first theories of language origins, but they face

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/zlatev2014-final.pdf - 2026-05-14

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Master’s Dissertation Structural Mechanics HENRIK JOHANSSON and JONATHAN OLLAR POLYMER FLOW IN PACKAGE SEALING PROCESS - A Coupled Eulerian-Lagrangian Numerical Approach Denna sida skall vara tom! Copyright © 2011 by Structural Mechanics, LTH, Sweden. Printed by Wallin & Dalholm Digital AB, Lund, Sweden, May, 2011 (Pl). For information, address: Division of Structural Mechanics, LTH, Lund Universi

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5175.pdf - 2026-05-14

Microsoft Word - Integrated analysis and design using graphic statics 180427

Microsoft Word - Integrated analysis and design using graphic statics 180427 Master’s Dissertation Structural Mechanics Report TV SM -5218 ERIK LA RSEN IN TEG R A TED STR U C TU R A L A N A LY SIS A N D D ESIG N U SIN G G R A PH IC STA TIC S ERIK LARSEN INTEGRATED STRUCTURAL ANALYSIS AND DESIGN USING GRAPHIC STATICS 5218HO.indd 15218HO.indd 1 2018-05-23 20:02:412018-05-23 20:02:41 DEPARTMENT OF CO

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5218.pdf - 2026-05-14

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The acceptability of a non-root phenomenon in different types of adverbial clauses in Icelandic Xindan Xu & Ásgrímur Angantýsson University of Iceland Abstract This paper discusses the relatively marked and uncommon subject-initial V3 word order in adverbial clauses in Icelandic and presents results from an online acceptability judgment survey conducted for this study. Following Badan and Haegeman

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_grimm/working_papers/2024-dec/Final_WPSS_XindanAsgrimur-1.pdf - 2026-05-14

Development of a detector (ALFA) to measure the absolute LHC luminosity at ATLAS

The ATLAS collaboration plans to determine the absolute luminosity of the CERN LHC at Interaction Point 1 by measuring the trajectory of protons elastically scattered at very small angles (μrad). A scintillating fibre tracker system called ALFA (Absolute Luminosity For ATLAS) is proposed for this measurement. Detector modules will be placed above and below the LHC beam axis in roman pot units at a

Processteknik och tillämpad biovetenskap

Processteknik och tillämpad biovetenskap | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen

https://www.lth.se/forskning/forskning-i-korthet/processteknik-och-tillaempad-biovetenskap/ - 2026-05-14