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Type 2 diabetes mellitus (T2DM) is a major disease affecting nearly 280 million people worldwide. Whilst the pathophysiological mechanisms leading to disease are poorly understood, dysfunction of the insulin-producing pancreatic beta-cells is key event for disease development. Monitoring the gene expression profiles of pancreatic beta-cells under several genetic or chemical perturbations has shed
Lung cancer is the worldwide leading cause of death from cancer. Epigenetic modifications such as methylation and changes in chromatin accessibility are major gene regulatory mechanisms involved in tumorigenesis and cellular lineage commitment. We aimed to characterize these processes in the context of neuroendocrine (NE) lung cancer. Illumina 450K DNA methylation data were collected for 1407 lung
BACKGROUND: Breastfeeding has beneficial effects on numerous health outcomes.OBJECTIVES: We investigated whether breastfeeding duration is associated with the development of early childhood autoimmunity, allergies, or obesity in a multinational prospective birth cohort.METHODS: Infants with genetic susceptibility for type 1 diabetes (n = 8676) were followed for the development of autoantibodies to
Background: The aim is to identify trajectories of precarious employment (PE) over time in Sweden to examine associations of these with the subsequent risk of myocardial infarction (MI) and stroke. Methods: This is a nation-wide register-based cohort study of 1,583,957 individuals aged 40 to 61 years old residing in Sweden between 2003-2007. Trajectories of PE as a multidimensional construct and s
Get a grip of your a guide to competence and career development Preface A company is no better than its collective competence. Your and your colleagues' knowledge, experience and ability to translate these competencies are therefore completely fundamental to Scania's success. At the same time, technological development is faster than ever. In order to be at the forefront, we need to constantly bui
Klimatstressad skog ändrar doft Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i vå
https://www.lth.se/article/klimatstressad-skog-aendrar-doft/ - 2026-05-14
Justifying Rational Planning: on the indeterminacy of pragmatic considerations Justifying Rational Choice: the role of success* Bruno Verbeek Leiden University, Netherlands §1 Introduction The theory of rational choice can be interpreted in several ways. One can regard the theory as a representing the choices of agents. The theory is interpreted as an empirical hypothesis for further research. Alt
https://www.fil.lu.se/hommageawlodek/site/papper/VerbeekBruno.pdf - 2026-05-15
Praktisk information | Matematikcentrum Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i våra system. Dessa c
https://www.maths.lu.se/utbildning/kandidatprogram-matematik/studentinformation/praktisk-information/ - 2026-05-14
Popular Abstract in Swedish Sandstäpp är ett starkt hotat växtsamhälle i Sverige som består av många specialiserade och hotade arter som t.ex. sandnejlika, tofsäxing och sandliljor. Exempel på hur en sandstäpp kan se ut hittas i Figur 1 i den Engelska sammanfattningen. Sandstäpp finns på sandig mark med kalk i ytjorden och ett lågt näringsinnehåll. Den karaktäriseras av ett uppbrutet växttäcke somA number of sandy grassland habitats of interest for biodiversity conservation can be found in Europe. One such habitat is the threatened xeric sand calcareous grassland, which is home to a large number of endangered species. It is characterized by a discontinuous vegetation cover, mainly consisting of stress-tolerant species favoured by nutrient-poor and dry conditions. The xeric sand calcareous
Inledning.indd 1 Per Erik Ljung Lunds universitet Per_Erik.Ljung@litt.lu.se Inledning: Mönster och möjligheter i studiet av översättning Det nns inget självklart sätt att skapa överblick över de 133 texter som här publiceras. Visserligen skapades en viss ordning genom de frågor vi gick ut med i vårt Call for papers inför konferensen, men ord- ningen kan som alltid vara rätt bedräglig. Vi frågade e
https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/introduction_v5_se.pdf - 2026-05-11
INTRODUCTION: The immune microenvironment plays a crucial role in the progression of colorectal cancer (CRC), but its variation across primary tumors and metastatic sites remains incompletely understood. In this study, we compared the composition and prognostic significance of the immune microenvironment in lung metastases, paired primary tumors, and liver metastases from a retrospective cohort of
Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experien
The use of prosthetic hands is limited in part by the lack of sensory feedback to the wearer. In order to provide sensory feedback, an adequate number of sensors must be integrated with the prosthesis. The WiseSkin project targets the use of artificial skin embedding ultra-low power wireless sensor nodes. This presentation provides an overview of the WiseSkin project and the current status of the
INTRODUCTION: Programmed death-ligand 1 (PD-L1) expression is used for treatment prediction in non-small cell lung cancer (NSCLC). While cytology may be the only available material in the routine clinical setting, testing in clinical trials has mainly been based on biopsies.METHODS: We included 2 retrospective cohorts of paired, concurrently sampled, cytological specimens and biopsies. Also, the l
Accurate histological classification and identification of fusion genes represent two cornerstones of clinical diagnostics in non-small cell lung cancer (NSCLC). Here, we present a NanoString gene expression platform and a novel platform-independent, single sample predictor (SSP) of NSCLC histology for combined, simultaneous, histological classification and fusion gene detection in minimal formali
CONTEXT: Neurotensin is associated with cardiometabolic diseases but its role with mortality risk in humans is unknown.OBJECTIVE: This work aims to examine the prediction of proneurotensin (Pro-NT) with respect to total and cause-specific mortality in a middle-aged cohort.METHODS: In the population-based middle-aged cohort (n = 4632; mean age, 57 years) of the Malmö Diet and Cancer Study, Pro-NT w
BACKGROUND: Post COVID-19 condition remains a complex and challenging issue, with diverse manifestations, despite accumulating research and clinical experience. Dyspnea is one of the most common symptoms reported in post COVID-19 condition. Cardiopulmonary exercise testing (CPET) offers a cohesive assessment of dyspnea and exercise limitations. The Nijmegen questionnaire is a form for assessment o
Constructing simulation models can be a complex and time-consuming task, in particular if the models are constructed from scratch or if a general-purpose simulation modeling tool is used. In this paper, we propose a model construction framework, which aims to simplify the process of constructing discrete event simulation models for emergency medical service (EMS) policy analysis. The main building
Corporate and State Responsibilities in Conflict-Affected Areas Radu Mares* Nordic Journal of International law, Volume 83, Number 3 (2014) pp. 293-345 Abstract Some of the emblematic cases of corporate-related infringements of human rights have appeared in unstable and violence-ridden zones, including armed conflict and other contexts with lower levels of conflict, internal disturbances, widespre
https://rwi.lu.se/app/uploads/2015/01/2014-Corporate-and-State-Responsibilities-in-Conflict-Areas-SSRN.pdf - 2026-05-15
