Search results

Bladder cancer is the ninth most common type of cancer globally, and the projected number of deaths is estimated to almost double by the year 2040. Immunotherapy with checkpoint inhibitors has revolutionized treatment of bladder cancer and can achieve durable responses; however, only a minority of patients respond. By identifying additional targets and treatment combinations, more patients could b

This study investigates the integration of Large Language Models with the TRIZ to improve problem solving and innovation in industrial product development. By combining the structured problem-solving framework of TRIZ with LLMs to process large amounts of data and generate ideas, this hybrid approach seeks to overcome the limitations of traditional TRIZ and optimize solution generation. In a case

Background: It is unclear whether thyroid hormone levels are associated with the risk of mortality, cardiovascular disease (CVD) events, or cancer in men with normal TSH. Objectives: We analyzed if serum free T4 (FT4) or TSH is associated with the risk of mortality, incident CVD events, or cancer in Swedish men. Methods: Elderly men (n = 1801; mean age 75 years) in the Gothenburg and Malmö subcoho

Background and aims: Animal studies have suggested that high salt intake might increase the risk of metabolic dysfunction-associated steatotic liver disease (MASLD), but results from populations are mixed, in part due to inadequate salt intake measurement. Salty taste preference is the primary factor leading to salt choice and can reflect habitual salt intake. However, no study has investigated t

The digital healthcare market has been growing rapidly due to the swift development of wearable devices. One notable advancement is the application of digital healthcare technology to vehicles, which is expected to provide a comfortable driving environment and prevent accidents. This study proposed user experience (UX) scenarios to apply and expand digital healthcare technology in vehicles, detail

Jorunn Joiner and Mari Komnæs also employ digital tools, albeit other ones, to shed light on the interaction between narratives of exceptionalism, travel, and place. In ‘Mapping Nordic Exceptionalism with GIS: The Odin Migration Theory and the Search for a Northern Heritage’, they use digital mapping tools to visualise the journeys of two travellers from different centuries in their search for a N

This paper explores the concept of peer-to-peer learning (P2PL) in the context of North-European small-scale forest owners. The aim is to develop a framework for initiating new and evaluating already existing forest owners’ P2PL communities. Design: Previous studies of peer-learning are used to determine and justify eight dimensions for forest owners’ P2PL. To demonstrate and test the operability

Intracellular application of the sulfonylurea tolbutamide during whole-cell patch-clamp recordings stimulated exocytosis >5-fold when applied at a cytoplasmic Ca2+ concentration of 0.17 microM. This effect was not detectable in the complete absence of cytoplasmic Ca2+ and when exocytosis was elicited by guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS). The stimulatory action could be antagonized by

Globular clusters host complex stellar populations whose chemical signatures suggest early (-) retention and reprocessing of stellar ejecta, yet direct evidence for intracluster gas is lacking. Here we present a unified theoretical framework for the evolution of gas in young globular clusters, and its implications for the production of multiple stellar populations. We show that low-velocity AGB wi

This dissertation examines the intense presence of the encounter with a number of artworks depicting sickrooms painted by Nordic artists by the end of the nineteenth century. To understand the intense presence enhanced through the encounter with these artworks, this dissertation argues that these paintings can be understood and examined as secular devotional images. Particular attention is devoted

Allergy, characterised by antibody responses of the IgE isotype, is a major health concern. The set of monoclonal human IgE used for studying the molecular mechanisms of allergies is limited. Single-cell sequencing offers opportunities to establish novel antibodies for researching, diagnosis, and treatment of allergies. We describe and exploit a pipeline for generating recombinant IgE directly fro

Abstract – Background: Cytological examination of a fine-needle aspirate (FNA) is a minimally invasive modality that is increasingly used in the diagnosis of lymphoma. Flow cytometry and other ancillary tests make an important contribution to the diagnostic value of FNAs of lymphoid lesions. This review follows the recent publication of the first edition of the WHO Reporting System for Lymph Node,

We present results of Population III (Pop III) formation in the megatron suite of simulations, which self-consistently follows radiation and non-equilibrium chemistry, and resolves gas at near-pc resolution in a Milky Way-mass progenitor at Cosmic Dawn. While the very first Pop III stars form in haloes with masses well below the atomic cooling limit, the majority of Pop III stars form in more mass

Many studies focusing on the design activity use the interview technique as a part of their investigation. Methodological discussions about the interview setting as the locus of a social interaction between the interviewer and the respondent and its implications for the interpretation of the obtained data are nevertheless rarely found in publications within our design community. Part I of this pub

Avtal Bilaga 1 Ändringar i Villkorsavtal-T Parterna är överens om följande ändringar i Villkorsavtal-T med giltighet från och med den 1 januari 2026 om inte annat anges. 1 § 5 kap. 14 § tredje stycket ska ha följande lydelse. Semesterlönegarantin för en heltidsarbetande arbetstagare utgörs från och med den 1 januari 20261 för varje uttagen betald semesterdag av ett belopp som motsvarar skillnaden

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/saco-s/dokument/avtal/2025/agv---saco-s-bilaga-1-13.pdf - 2026-05-23

Civ ilingenjörsutbildning i teknisk nanovetenskap: utbildningsplan Civ ilingenjörsutbildning i teknisk nanovetenskap Programkod: TATNA Omfattning: 300 högskolepoäng Tillträdesnivå: Grundnivå Beslutsfattare: Programledning N Utbildningsplanens giltighet: 2020/21 Utbildningsplanen fastställd: 2020-02-14 Förutom utbildningsplanen för denna utbildning gäller även gemensamma föreskrifter och informatio

https://www.student.lth.se/fileadmin/lth/utbildning/studiehandboken/20_21/N_Uplan_20-21.pdf - 2026-05-23

Tumor-associated macrophages (TAMs) continuously fine tune their immune modulatory properties, but how gene expression programs coordinate this immune cell plasticity is largely unknown. Selective mRNA translation, controlled by MNK1/MNK2 and mTOR pathways impinging on eIF4E, facilitates reshaping of proteomes without changes in abundance of corresponding mRNAs. Using polysome profiling developed

Background: A pilot study investigating proteomic profiles from 78 patients from the Target Temperature Management after Out-of-hospital Cardiac arrest (TTM) trial revealed 35 proteins associated to functional outcome, and six proteins associated to targeted temperature management at 33 °C. We present the protocol for a study investigating proteomic profiles in the full cohort of the TTM-trial bio

Popular Abstract in Swedish Detta är en avhandling om hur en del av vårt meningsskapande går till, sedd genom åtta studenters användning av sina kontextuella resurser. Den handlar om hur vi lyssnar till auditiva, visuella och upplevda röster, och hur vi talar med stöd av dessa röster när vi skapar och utvecklar vår egen röst. Detta kallar jag för rapporterat lyssnande, d.v.s. dessa yttranden visarThis thesis has two points of departure and four main purposes. The first point of departure concerns the narrow perspective of the listening skill in Swedish. The first purpose is to show the lack of attention to the listening skill in research and mother tongue education in the Swedish compulsory school. Educational documents from 1842 to 2000 about Swedish as a school subject are examined from