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Semiosis and the elusive final interpretant of understanding* GÖRAN SONESSON Abstract While the conceptual history of the sign, as recounted by John Deely in Four ages of understanding, is immensely enlightening, history is never enough. If, before Augustine, it had occurred to no one that such diverse phenomena as are covered by this term had something in common, and if, in the time of Aquinas,

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/semi_2010_178_511-624.pdf - 2026-05-09

Genomic imprinting analyses identify maternal effects as a cause of phenotypic variability in type 1 diabetes and rheumatoid arthritis

Imprinted genes, giving rise to parent-of-origin effects (POEs), have been hypothesised to affect type 1 diabetes (T1D) and rheumatoid arthritis (RA). However, maternal effects may also play a role. By using a mixed model that is able to simultaneously consider all kinds of POEs, the importance of POEs for the development of T1D and RA was investigated in a variance components analysis. The analys

Synthesis of alkylgalactosides using whole cells of Bacillus pseudofirmus species as catalysts

Whole cells of alkaliphilic Bacillus pseudofirmus AR-199, induced for beta-galactosidase activity, were used for the synthesis of 1-hexyl-beta-D-galactoside and 1-octyl-beta-D-galactoside, respectively, by transglycosylation reaction between lactose and the corresponding alcohol acceptor. The product yield was strongly influenced by the initial water content in the reaction mixture. Water content

Closure after gastrostomy button

A gastrostomy device is removed from the gastrostoma when no longer needed. The aim of the study was to test the hypothesis of whether it is possible for the surgeon to decide which stoma has to be closed with a gastroraphy and which to leave for a spontaneous closure within a reasonable period of time. Out of a cohort of 321 patients, who had been operated with a video-assisted gastrostomy, we in

Understanding the Role of Personality in Explaining Associations Between Marital Quality and Parenting

Analyses assessed the degrees to which personality accounts for associations between marital quality and parenting and mediates genetic contributions to these relationships. Participants included 318 male and 544 female same-sex twin pairs from the Twin and Offspring Study in Sweden. All twins completed self-report measures of marital quality and personality (anxiousness, aggression, sociability).

Adopting 3-Year Screening Intervals for Sight-Threatening Retinal Vascular Lesions in Type 2 Diabetic Subjects Without Retinopathy

OBJECTIVE-To report the incidence of sight-threatening vascular lesions in type 2 diabetic subjects without retinopathy after adopting a 3-year interval screening program. RESEARCH DESIGN AND METHODS-In all, 1,691 type 2 diabetic subjects with no detectable retinopathy in two 50 degrees red-free fundus photographs were scheduled for follow-up with photography 3 years later. Age at diabetes diagnos

A 1.6-2.6GHz 29dBm Injection-Locked Power Amplifier with 64% peak PAE in 65nm CMOS

This paper presents a wideband CMOS power amplifier intended for cellular handset applications. The circuit exploits injection locking to achieve a power gain of 20.5dB from a single stage amplifier. The maximum output power of 29dBm, with a peak drain- and power-added-efficiency (PAE) of 66% and 64%, respectively, occurs at a center frequency of 2GHz with a 3V supply. A cross-coupled cascode topo

Isokinetic behaviour in gas phase catalytic haloarene hydrodehalogenation reactions: Mechanistic considerations

Compensation behaviour is established for the gas phase hydrodehalogenation of a range of haloarenes over a common Ni/SiO2 catalyst. Analysis of the experimental results delivers an isokinetic temperature (T-iso) at 658 +/- 2K associated with the following reactants: chlorobenzene, 4-chlorotoluene, 3-chlorophenol, 1,3,-dichlorobenzene, 4-chlorophenol, 3,5-dichlorophenol, 1,4-dichlorobenzene, bromo

A Case with Bladder Exstrophy and Unbalanced X Chromosome Rearrangement

Introduction Bladder exstrophy is a rare congenital malformation of the bladder and is believed to be a complex disorder with genetic and environmental background. We describe a young adult female with an isolated bladder exstrophy and with an X chromosome aberration. Patients and Methods Karyotyping identified an X chromosome rearrangement that was further characterized with array comparative gen

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and BRCA2 mutation carriers who are at high risk of EOC. After imputation to 1000 Genomes Project data, we assessed associations of 11 million genetic variants with EOC risk from 15,437 cases unselected for family history

Trade Facilitation and the Extensive Margin

The literature on trade facilitation has mostly focused on implications for trade volumes. However, recent theoretical contributions have emphasized that trade costs – such as transaction costs related to cross-border trade procedures – affect both the traded volumes of “old” goods (the intensive margin) and the range of traded goods (the extensive margin). This paper therefore tests whether trade

System level cache prefetching algorithms for complex GPU workloads

Prefetching is a well known concept for CPUs but for GPUs it is fairly unexplored. The memory management of a GPU plays a crucial role in its performance, and cache prefetching has the potential to lower the overall latency. This thesis compares different types of prefetching methods for GPUs and remaking some CPU prefetchers to fit the GPU architecture. All these prefetchers were then put inside

Striking a balance: parties and government debt in an age of change. A comparative analysis of mainstream parties in advanced Western democracies

In recent decades, internal and external circumstances have increased the pressure on European states and the United States to act in response to such circumstances. The return of war on the European continent, shifting trade relations, climate change and its devasting effects on society and an aging population are all putting pressure on public finances. The aim of this study is to investigate th

Recent and future trends in synthetic greenhouse gas radiative forcing

Atmospheric measurements show that emissions of hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons are now the primary drivers of the positive growth in synthetic greenhouse gas (SGHG) radiative forcing. We infer recent SGHG emissions and examine the impact of future emissions scenarios, with a particular focus on proposals to reduce HFC use under the Montreal Protocol. If these proposals are