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Decrease in high density lipoprotein cholesterol during prolonged storage. CELL Study Group

Different studies on the stability of high density lipoprotein cholesterol (HDL) in frozen serum or plasma have yielded conflicting results, namely increase, decrease, or no change at all during prolonged storage under freezing conditions. As part of a major trial on lipid-lowering strategies we statistically demonstrated a time-related decrease in HDL cholesterol during storage up to 46 months at

Analysis of complications after repair of hypospadias

We have reviewed 184 patients after repair of primary hypospadias. They were operated on and followed-up according to a standard protocol, and the senior author (HS) participated in all operations. The patients were reconstructed using a Byars two-stage procedure ( n = 102) or a Scuderi ( n = 29) or Mathieu ( n = 41) single-stage procedure. The rest ( n = 12) just had a removal of the chordee with

Increased Cause-specific Mortality in Patients with Mild and Severe Psoriasis: A Population-based Swedish Register Study

Several studies have shown excess risk for a number of comorbidities in patients with psoriasis compared with the general population, but data on cause-specific mortality in this patient population are limited. The aim of this study was to estimate the associations of psoriasis and 12 specific causes of death and all-cause mortality in patients with mild and severe psoriasis. The study was based o

Structures of NiCd6+delta (-0.32

The crystal structures of the binary cadmium-rich complex metal alloys NiCd6+delta (-0.32 <= delta <= 0.35) and NiCd1+delta (0 <= d <= 0.05) were studied by means of single crystal X-ray diffraction. The partitioning of the NiCd6+delta structure into clusters grouped around all 16 high symmetry points of the face centered cubic cell leads to the identification of two partial structures forming rep

Measurement of the cross section for the production of a W boson in association with b-jets in pp collisions at root s=7 TeV with the ATLAS detector

A measurement is presented of the cross section for the production of a W boson with one or two jets, of which at least one must be a b-jet, in pp collisions at root s = 7 TeV. Production via top decay is not included in the signal definition. The measurement is based on 35 pb(-1) of data collected with the ATLAS detector at the LHC. The W + b-jet cross section is defined for jets reconstructed wi

Trends in the prevalence of gestational diabetes mellitus in southern Sweden, 2003-2012.

There is accumulating evidence that gestational diabetes (GDM) is a growing problem. The lack of internationally standardized diagnostic procedures prevents consistent diagnosis and the burden of GDM must be determined in country-specific studies. In southern Sweden, GDM is defined as a 2-hour capillary plasma glucose concentration of ≥10.0 mmol/L during a universal 75 g oral glucose tolerance tes

Marital status, cohabitation, and the risk of preterm birth in Europe: where births outside marriage are common and uncommon.

This article explores whether the impact of marital status on the risk of preterm birth varies in relation to marital practices in the population, defined by the proportion of out-of-marriage births. Data come from a case–control study of the determinants of preterm birth in 16 European countries (5456 cases and 8234 controls). There is a significantly elevated risk of preterm birth associated wit

Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies.

Disease gene identification is still a challenge despite modern high-throughput methods. Many diseases are very rare or lethal and thus cannot be investigated with traditional methods. Several in silico methods have been developed but they have some limitations. We introduce a new method that combines information about protein-interaction network properties and Gene Ontology terms. Genes with high

Mixed Micelles of Oppositely Charged Diblock Copolymers - a Dynamic and Static Light Scattering Study

Polymerer är naturliga eller syntetiska makromolekyler som är uppbyggda av flera repeterande enheter, monomerer. I blocksampolymerer är de ingående typerna av monomerer fördelade i olika block i polymeren, t.ex. A och B. Blocksampolymerer är ett intressant forskningsområde med möjliga tillämpningar inom bland annat läkemedelstransport, så kallad controlled drug release, d.v.s för kontrollerad frisIn the present work, the formation of complex coacervate micelles and aggregates of the oppositely charged diblock copolymers poly(N-isopropylacrylamide)27-b-poly((3-acrylamidopropyl)trimethylammoniumchloride)15 [PNIPAAM27-b-PAMPTMA15(+)] and poly(N-isopropylacrylamide)27-b-poly(2-acrylamido-2-methyl-1-propanesulfonic sodium)15 [PNIPAAM27-b-PAMPS15(-)] in aqueous solution have been studied at diff

The Effect of Depression on Pattern Separation Task Performance

The aim of this study was to investigate a possible relationship between depression and memory performance, hypothesizing a decrease in performance among participants with depression tendencies. The cognitive memory task of pattern separation was tested with four different levels of difficulty by use of a computerized memory test and the self-rating MADRS-S depression scale was used to assess the

Ledarskapsstil och organisatoriskt engagemang i relation till de anställdas välbefinnande

The aim of this study was to gain knowledge about leadership style and its relation to coworker's wellbeing. Of special interest was to find the best predictor variable of wellbeing. A further aim was to study differences between males and females in organizational commitment and wellbeing. A questionnaire was distributed to 100 employees in Telia, a Swedish telecom company. 62 questionnaires

Activated protein C resistance in patients with peripheral vascular disease

PURPOSE: The frequency of activated protein C (APC) resistance, caused by factor V R506Q gene mutation and abnormal APC ratio, in patients with peripheral vascular diseases was analyzed. METHODS: All patients electively admitted to the vascular ward unit of our tertiary care academic medical center from January 1995 through October 1996 (n = 679) were prospectively analyzed using an APC-resistance

Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

Subjects with impaired glucose tolerance (IGT) are usually overweight and exhibit insulin resistance with a defective compensation of insulin secretion. In this study, we sought to establish the interrelation between insulin secretion and insulin sensitivity after oral glucose in non-obese subjects with IGT and we also examined this interrelation in relation to the 2 main incretins, glucagon-like