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Functional C1-inhibitor diagnostics in hereditary angioedema: Assay evaluation and recommendations

Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The most widespread underlying genetic deficiency is a heterozygous deficiency of the serine protease inhibitor Cl esterase inhibitor (C1-Inh). In addition to low C4 levels, the most important laboratory parameter for correct diagnosis of HAE or angioedema du

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Je m'appele XX. J'ai seize ans. J'abbite en XX avec ma famille. Notre maison n'est pas grande et n'est pas petite. Il y a quatre chambre de dormir, deux salles de bains et un cuisine. Il y a aussi un salle de vivre. Dans mon chambre j'ai un lit, un ordinateur et un telé. Il y a aussi un train modèle que je suis en train de (sälja). J'ai deux souers, une qui a quinze ans et une qui a six ans. Elles

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_longitudinal/conny/Texte_4.txt - 2026-05-04

Arsine, Stibine and Phosphine Derivatives of [Fe2(CO)6(μ-bdt)] (bdt = Benzenedithiolate) : Syntheses, Structures and Spectroscopic and Electrocatalytic Studies

The reactivity of the benzenedithiolate (bdt)-bridged complex [Fe2(CO)6(µ-bdt)] with arsine, stibine and phosphine ligands has been studied. The new mono- and disubstituted complexes [Fe2(CO)5(EPh3)(µ-bdt)] (E = As, 1; E = Sb 3) and [Fe2(CO)4(EPh3)2(µ-bdt)] (E = As, 2; E = Sb, 4) and the previously reported [Fe2(CO)4(PPh2H)2(µ-bdt)] (5) have been prepared by Me3NO-initiated carbonyl substitution r

Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study

Objective: Data remain divergent regarding the activational effects of endogenous hormones on adult cognitive function. We examined the association between cognition, hormones and androgen receptor (AR) CAG repeat length in a large cohort of men. Design: Community-based, cross-sectional study of 3369 men aged 40-79 years. Methods: Cognition tests were the Rey-Osterrieth Complex Figure, Camden Topo

"Vi kanske kommer igen, om det låser sig" : Kvinnors och mäns möte med familjerådgivning.

Popular Abstract in Swedish Kring familjeproblematiken och för behandlingen av familjekonflikter har det svenska samhället organiserat olika sociala verksamheter som traditionellt regleras av Socialtjänstlagen. Familjerådgivningen är en av dessa verksamheter och definieras som en psykoterapeutisk behandling, till vilken en eller båda parter vänder sig oftast på frivillig basis när de upplever att

Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest

BACKGROUND: Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome p

A comparison of different orthogonal techniques for the investigation of the conformational stability of NIST mAb in liquid formulations

Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa