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The rich Mayan weaving tradition in Guatemala has survived even though the indigenous population has been subject to centuries of hardship and oppression. After conducting a field study and scrutinising the commercialisation process of the traditional designs in five different producer cooperatives of which, for the purpose of this thesis, some are characterised as weaving cooperatives and others

The 19th century in Sweden, like in many other European countries, saw a largedecline in the quantity of Neo-Latin literary production. However, a range of skillful Latin poets may be named from this period: Johan Lundblad, Johan Tranér, Emil Söderström, Johan Bergman and others, engaged as well in translating from Swedish into Latin as in composing poems of their own. It was also in the 19th cent

Activating signaling mutations are common in acute leukemia with KMT2A (previously MLL) rearrangements (KMT2A-R). These mutations are often subclonal and their biological impact remains unclear. Using a retroviral acute myeloid mouse leukemia model, we demonstrate that FLT3 ITD, FLT3 N676K, and NRAS G12D accelerate KMT2A-MLLT3 leukemia onset. Further, also subclonal FLT3 N676K mutations accelerate

BACKGROUND: Bacterial surfaces are complex systems, constructed from membranes, peptidoglycan and, importantly, proteins. The proteins play crucial roles as critical regulators of how the bacterium interacts with and survive in its environment. A full catalog of the motifs in protein families and their relative conservation grade is a prerequisite to target the protein-protein interaction that bac

You whistle – and ask, am I alone in here?A whistle emanates from the gut, proceeding to circulate beyond the body, as an absent presence that is felt rather than seen. Whistling in the dark — a nonchalant gesture set within an anxious environment; to summon your courage in the face of projected danger.In the Netherlands, we find ourselves placed at a critical juncture. Much has been said on the r

The growing complexity of the concept of gender highlights the importance for a deeper understanding of the diversity underlying this construct. Recent studies have shown large numbers of individuals experiencing non-conforming feelings with their sex assigned at birth, emphasising the need to gain a better understanding of gender identities outside the binary system, one of these being non-binary

Climate change is expected to increase the frequency and intensity of the most severe weather-related hazards over the coming decades. The poor in developing countries are particularly susceptible to climate change, often living in informal or precarious settlements. In order to reduce the vulnerability in those areas and strengthen people´s capacities to adapt to climate change, there is a need f

Purpose: To describe the phenotype and genotype in a young woman with Danon disease. Methods: The patient underwent an ophthalmic examination including best corrected visual acuity (BCVA), fundus photography and fundus autofluorescence (FAF), full-field electroretinography (full-field ERG), multifocal ERG, optical coherence tomography (OCT) and SAP-Humphrey 30–2 at the ages of 20 and 25. Electrooc