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Popular Abstract in Swedish Avhandlingen behandlar inlärning av italienska som ett av två modersmål (svenska/italienska) hos tvåspråkiga barn och som andraspråk hos svenska vuxna som lär sig italienska i Italien. Särksilt fokus ligger på ett barn som lär sig italienska som ett av två modersmål i Sverige och vi ställer oss frågan om hans italienska kommer att utvecklas som hos italienska enspråkigaThis thesis deals with the development of the DP (the Determiner Phrase) in bilingual first (2L1) and in adult second (L2) language acquisition of Italian, with a focus on a case study of Italian as a second first language. The thesis suggests that the bilingual children and the Swedish adult learners develop the Italian DP differently. The child acquiring Italian as a second first language develo

4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer

Estrogen receptor (ER) positive tumors represent the majority of breast malignancies, and are effectively treated with hormonal therapies, such as tamoxifen. However, in the recurrent disease resistance to tamoxifen therapy is common and a major cause of death. In recent years, in-depth proteome analyses have enabled identification of clinically useful biomarkers, particularly, when heterogeneity

Two types of muscarinic acetylcholine receptors in Drosophila and other arthropods

Muscarinic acetylcholine receptors (mAChRs) play a central role in the mammalian nervous system. These receptors are G protein-coupled receptors (GPCRs), which are activated by the agonists acetylcholine and muscarine, and blocked by a variety of antagonists. Mammals have five mAChRs (m1-m5). In this study, we cloned two structurally related GPCRs from the fruit fly Drosophila melanogaster, which,

The exosome associates cotranscriptionally with the nascent pre-mRNP through interactions with heterogeneous nuclear ribonucleoproteins

Eukaryotic cells have evolved quality control mechanisms to degrade aberrant mRNA molecules and prevent the synthesis of defective proteins that could be deleterious for the cell. The exosome, a protein complex with ribonuclease activity, is a key player in quality control. An early quality checkpoint takes place cotranscriptionally but little is known about the molecular mechanisms by which the e

Evolution of chain migration in an aerial insectivorous bird, the common swift Apus apus

Spectacular long-distance migration has evolved repeatedly in animals enabling exploration of resources separated in time and space. In birds, these patterns are largely driven by seasonality, cost of migration, and asymmetries in competition leading most often to leapfrog migration, where northern breeding populations winter furthest to the south. Here, we show that the highly aerial common swift

Glorifieras självmord i japansk film? - En tolkning av Seppuku och Jisatsu saakuru

This thesis investigates how suicide is portrayed in japanese films and if it is glorified or not. Two films have been chosen for analysis, Seppuku (Harakiri, Masaki Kobayashi, 1962) and Jisatsu saakuru (Suicide Club/Circle, Shion Sono, 2001). The purpose of the thesis is to find out if suicide is glorified in these two films and to examine the historical and reality connections of the timeperiods

Effects of x-ray free-electron laser pulse intensity on the Mn K β 1,3x-ray emission spectrum in photosystem II - A case study for metalloprotein crystals and solutions

In the last ten years, x-ray free-electron lasers (XFELs) have been successfully employed to characterize metalloproteins at room temperature using various techniques including x-ray diffraction, scattering, and spectroscopy. The approach has been to outrun the radiation damage by using femtosecond (fs) x-ray pulses. An example of an important and damage sensitive active metal center is the Mn4CaO

The changing landscape of genetic testing and its impact on clinical and laboratory services and research in Europe

The arrival of new genetic technologies that allow efficient examination of the whole human genome (microarray, next-generation sequencing) will impact upon both laboratories (cytogenetic and molecular genetics in the first instance) and clinical/medical genetic services. The interpretation of analytical results in terms of their clinical relevance and the predicted health status poses a challenge

Energy Efficiency : What Has Research Delivered in the Last 40 Years?

This article presents a critical assessment of 40 years of research that may be brought under the umbrella of energy efficiency, spanning different aggregations and domains-from individual producing and consuming agents to economy-wide effects to the role of innovation to the influence of policy. After 40 years of research, energy efficiency initiatives are generally perceived as highly effective.

Care as repair, but whose responsibility? : Front-line health workers’ resourcefulness in implementing a PMTCT tracing policy in Kenya

Defaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study explores the role of tracers—community volunteers, retention workers, and mentor mothers—in implementing such policy across six facilities in Western Kenya. It uses Defaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study explores the role of tracers—community volunteers, retention workers, and mentor mothers—in implementing such policy across six facilities in Western Kenya. It uses

EPOS2020/EUFOREA expert opinion on defining disease states and therapeutic goals in CRSwNP

Severe chronic rhinosinusitis with nasal polyps (CRSwNP), a form of diffuse bilateral (usually type 2) CRS, is a debilitating disease with a significant impact on quality of life (QoL). With novel knowledge and treatment options becoming available, there is a growing need to update or revise key definitions to enable communication across different specialties dealing with CRS, and to agree on nove

A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5

B lymphopoiesis is orchestrated by lineage-specific transcription factors. In B cell progenitors, lineage commitment is mediated by Pax5, which is commonly mutated in B cell acute lymphoblastic leukemia. Despite its essential role in immunity, the mechanisms regulating Pax5 function remain largely unknown. Here, we found that the NAD+-dependent enzyme SIRT7 coordinates B cell development through d

Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection

The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, we used high-resolution shotgun metagenomics and targeted metabolomic analysis to characterize influenza-associated changes in the composition and metabolism of the mouse gut microbiota. We observed several taxonomic-level changes on day (D)7 post-infection, including

Climate, peace, and conflict—past and present: Bridging insights from historical sciences and contemporary research

Concern has risen that current global warming and more frequent extreme events such as droughts and floods will increase conflict around the world. This concern has spurred both social science research on contemporary climate, peace, and conflict as well as research in the historical sciences on past climate, weather, warfare, and violence. This perspectives article compares these two fields of sc

TMEM160 Promotes Tumor Growth in Lung Adenocarcinoma and Cervical Adenocarcinoma Cell Lines

The Chromosome-Centric Human Proteome Project (C-HPP) is an international initiative. It aims to create a protein list expressed in human cells by each chromosomal and mitochondrial DNA to enhance our understanding of disease mechanisms, akin to the gene list generated by the Human Genome Project. Transmembrane protein 160 (TMEM160) is a member of the transmembrane proteins (TMEM) family. TMEM pro

Doppler shifted transient sodium detection by KECK/HIRES

We carried out the first high-resolution transit observations of the exoplanet WASP-49 Ab with Keck/HIRES. Upon custom wavelength calibration we achieve a Doppler RV precision of < 60 m s−1. . This is an improvement in RV stability of roughly 240 m s−1 with respect to the instrument standard. We report an average sodium flux residual of (Formula presented) per cent t (8.0σ) comparable to previous

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Möte med en mångsysslare Möte med en mångsysslare Möte med en mångsysslare Möte med en mångsysslare GULDREGN ÖVER LTH • HAN BLIR DOKTOR PÅ LIVETS VÄRDE • FARLIGA PARTIKLAR Nummer 2 • 2004 LTH NYTT © R ik sb an ke n 3LT H - n y t t n u m m e r 2 • 2 0 0 4 Ni såg det direkt, väl? Tidningens logga är annorlunda. Den tidning ni nu håller i handen har också ett annorlunda format än tidi- gare. Möjlighe

https://www.lth.se/fileadmin/lth/omlth/kommunikation/lthnytt/lthn04_2.pdf - 2026-05-11

I’m pleased and honoured to be asked to present the first talk

I’m pleased and honoured to be asked to present the first talk Alignment of tonal targets: 30 years on Bob Ladd University of Edinburgh Text of a talk presented in Lund on 10 January 2007, at a symposium in Honour of Gösta Bruce’s 60th birthday. References are missing and some details of the works discussed are presented more informally than would be appropriate in print. Please keep this in mind

https://konferens.ht.lu.se/fileadmin/user_upload/conference/waatisp/pdf/ladd_lundbruce60publicfina.pdf - 2026-05-11