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Snakes and Ladders: Learning words in a foreign language
Snakes and Ladders: Learning words in a foreign language Snakes and Ladders: Learning words in a foreign language Published 17 December 2020 Lari-Valtteri Suhonen successfully defended his PhD thesis "Snakes and Ladders – Developmental Aspects of Lexical-Conceptual Relationships in the Multilingual Mental Lexicon" last week. The faculty opponent was Jeanine Treffers-Daller, University of Reading.
https://www.sol.lu.se/en/article/snakes-and-ladders-learning-words-in-a-foreign-language/ - 2026-05-04
Statistical parametric mapping of functional MRI data using wavelets adapted to the cerebral cortex
Wavelet approaches have been successfully applied to the detection of brain activity in fMRI data. Spatial activation patterns have a compact representation in the wavelet domain. However, classical wavelets designed for regular Euclidean spaces are not optimal for the topologically complicated gray-matter (GM) domain where activation is expected. We hypothesized that wavelet bases that are adapte
Supramolecular assembly of thermoresponsive steroidal surfactant with oppositely charged thermoresponsive block copolymer
Supramolecular rearrangements are crucial in determining the response of stimuli sensitive soft matter systems such as those formed by mixtures of oppositely charged amphiphiles. Here mixtures of this kind were prepared by mixing the cationic block copolymer pAMPTMA30-b-pNIPAAM120 and an anionic surfactant obtained by the modification of the bile salt sodium cholate. As pure components, the two co
Improving the likelihood of neurology patients being examined using patient feedback
We aimed to establish whether recall of elements of the neurological examination can be improved by use of a simple patient assessment score. In a previous study we demonstrated that in-patients referred to neurology at two United Kingdom (UK) hospitals were not fully examined prior to referral; we therefore designed a larger quality improvement report with 80% power to detect a 10% increase in te
Long-term risk of renal and urinary tract diseases in childhood cancer survivors : A population-based cohort study
Background Childhood cancer has been associated with long-term risk of urinary tract diseases, but risk patterns remain to be comprehensively investigated. We analysed the lifetime risk of urinary tract diseases in survivors of childhood cancer in the Nordic countries. Methods We identified 32,519 one-year survivors of childhood cancer diagnosed since the 1940s and 1950s in the five Nordic cancer
Bin-packing based optimisation of EON Networks with S-BVTs
In the paper we address an important problem in minimum cost design of Elastic Optical Networks (EON), namely the problem of optimizing the configurations of Sliceable-Bandwidth Variable Transceivers (S-BVT) at the EON nodes. We first show how this optimization problem can be viewed and modeled as a combination of three bin-packing subproblems, with additional constraints ensuring feasibility of t
Factor V:Q506 mutation and anticardiolipin antibodies in systemic lupus erythematosus
Inherited resistance to activated protein C (APC resistance) is an important risk factor of venous thrombosis. It is caused by a point mutation in the gene coding for coagulation factor V, called FV:Q506. Arterio-venous thrombosis is a common and serious medical problem in patients with systemic lupus erythematosus (SLE). We studied the prevalence of the factor V mutation associated with APC resis
Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
Retinoid X receptors (RXRs) play key roles in many physiological processes in both the periphery and central nervous system. In addition, RXRs form heterodimers with other nuclear receptors to exert their physiological effects. The nuclear receptor related 1 protein (NURR1) is particularly interesting because of its role in promoting differentiation and survival of dopamine neurons. However, only
Can suitable candidates for levodopa/carbidopa intestinal gel therapy be identified using current evidence?
Advanced Parkinson's disease (APD) is characterized by increased functional disability, caused by motor complications, the presence of axial symptoms, and emergent disease- and drug-related non-motor symptoms. One of the advanced therapies available is intrajejunal infusion of levodopa/carbidopa intestinal gel (LCIG); however, patient selection for this treatment is sometimes difficult, particular
Screening protocols to monitor respiratory status in primary immunodeficiency disease : findings from a European survey and subclinical infection working group
Many patients with primary immunodeficiency (PID) who have antibody deficiency develop progressive lung disease due to underlying subclinical infection and inflammation. To understand how these patients are monitored we conducted a retrospective survey based on patient records of 13 PID centres across Europe, regarding the care of 1061 adult and 178 paediatric patients with PID on immunoglobulin (
Studies of Mammalian Mitochondrial Genomes with Special Emphasis on the Perissodactyla
Mammalian mitochondrial DNA (mtDNA) is a closed-circular double-helix molecule which contains two rRNA genes, 13 protein-coding genes, and 22 tRNA genes. The molecule has become a popular tool in phylogenetic analyses owing to its relatively high evolutionary rate, simple genetic structure, small size, and compact gene arrangement. The order Perissodactyla includes the extant families Equidae, Ta
Disentangling drivers of soil microbial potential enzyme activity across rain regimes : An approach based on the functional trait framework
The functional trait framework provides a powerful corpus of integrated concepts and theories to assess how environmental factors influence ecosystem functioning through community assembly. While common in plant ecology, this approach is under-used in microbial ecology. After an introduction of this framework in the context of microbial ecology and enzymology, we propose an approach 1) to elucidat
Genetic parameters for noncoagulating milk, milk coagulation properties, and detailed milk composition in Swedish Red Dairy Cattle
The rennet-induced coagulation ability of milk is important in cheese production. For Swedish Red Dairy Cattle (RDC), this ability is reduced because of a high prevalence of noncoagulating (NC) milk. In this study, we simultaneously combined genetic parameters for NC milk, milk coagulation properties, milk composition, physical traits, and milk protein composition. Our aim was to estimate heritabi
Clique is hard on average for regular resolution
We prove that for k ≪ 4 n regular resolution requires length nΩ(k) to establish that an Erdős–Rényi graph with appropriately chosen edge density does not contain a k-clique. This lower bound is optimal up to the multiplicative constant in the exponent, and also implies unconditional nΩ(k) lower bounds on running time for several state-of-the-art algorithms for finding maximum cliques in graphs.
How Limited Interaction Hinders Real Communication (and What It Means for Proof and Circuit Complexity)
We obtain the first true size-space trade-offs for the cutting planes proof system, where the upper bounds hold for size and total space for derivations with constantsize coefficients, and the lower bounds apply to length and formula space (i.e., number of inequalities in memory) even for derivations with exponentially large coefficients. These are also the first trade-offs to hold uniformly for r
Measuring childhood cancer late effects : evidence of a healthy survivor effect
Introduction: Given considerable focus on health outcomes among childhood cancer survivors, we aimed to explore whether survivor bias is apparent during long-term follow-up of childhood cancer survivors. Methods: We identified all 1-year survivors of cancer diagnosed before 20 years of age in Denmark, Finland, Iceland, and Sweden. From the general population, we randomly sampled a comparison cohor
Gain-of-function mutation in complement C2 protein identified in a patient with aHUS
Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure
Background The methyl ester form of fumaric acid named dimethyl fumarate (DMF) is an effective mould-growth inhibitor. Its irritating and sensitizing properties were demonstrated in animal models. Recently, DMF has been identified as responsible for furniture contact dermatitis in Europe. Objective To describe the clinical manifestations, patch test results, shoe chemical analysis, and source of e
Occupational exposure to NDMA and NMor in the European rubber industry
Many nitrosamines are suspected of being human carcinogens, with the highest concentrations in the environment being measured in the rubber industry. Time trends of personal exposure to N-nitrosodimethylamine (NDMA) and to N-nitrosomorpholine (NMor) during the past two decades in the German rubber industry were analysed and compared with cross-sectional studies in the same period in the Netherland
