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The early science results from the new generation of high-resolution stellar spectroscopic surveys, such as Galactic Archaeology with HERMES (GALAH) and the Gaia European Southern Observatory survey (Gaia-ESO), will represent major milestones in the quest to chemically tag the Galaxy. Yet this technique to reconstruct dispersed coeval stellar groups has remained largely untested until recently. We
In the present contribution, we report a theoretical investigation of the magnetic properties of the dihydrogen-evolving enzyme [FeFe]-hydrogenase, based on both DFT models of the active site (the H-cluster, a Fe6S6 assembly including a binuclear portion directly involved in substrates binding), and QM/MM models of the whole enzyme. Antiferromagnetic coupling within the H-cluster has been treated
The pattern of endocrine disorders in long-term survivors of childhood cancer has not been investigated comprehensively. Here, we aimed to assess the lifetime risk of these disorders in Nordic survivors of childhood cancer.
Climate change is expected to have the greatest impact on the world's economically poor. In the Sahel, a climatically sensitive region where rain-fed agriculture is the primary livelihood, expected decreases in water supply will increase food insecurity. Studies on climate change and the intensification of the water cycle in sub-Saharan Africa are few. This is due in part to poor calibration of mo
New laminar burning velocity measurements of 85: 15% (by volume) H-2-CO and H-2-N-2 mixtures with O-2-He oxidizer are reported at lean conditions and elevated pressures (1-10 atm). Experiments are conducted using the heat flux method at initial temperature of 298 K. In this technique a near adiabatic flame is stabilized by balancing the heat loss from the flame to the burner with heat gain to the
During the last five decades, survival of childhood cancer has increased from 25% to 80%. At the same time, however, it has become evident that survivors experience a broad range of therapy-related late adverse health effects. The aim of the Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study is to investigate long-term health consequences of past and current therapies in order to impr
The individual lifetimes of three low-lying states in the proton-decaying well-deformed rotational band in the second minimum of the N = Z nucleus Cu-58 were determined. Doppler-shift attenuated gamma -ray lineshapes were analyzed following the fusion-evaporation reaction C-40,(Mg-24,1 alpha 1p1n)Cu-58 and using the EUROBALL gamma -ray spectrometer coupled to ancillary detector systems. The deduce
Endoderm development is an area of intense interest in developmental biology, but progress has been hampered by the lack of specific markers for differentiated endodermal cells. In an unbiased secretion cloning screen of Xenopus gastrula embryos we isolated a novel gene, designated Darmin. Darmin encodes a secreted protein of 56 kDa containing a peptidase M20 domain characteristic of the glutamate
BACKGROUND AND OBJECTIVES: Atherosclerosis is a multifactorial disease, in part characterized by chronic inflammatory changes in the vessel wall and loss of normal physical and biochemical interactions between endothelial cells and smooth muscle cells. Previous studies [Hu J., Cotgreave IA. J Clin Invest; 99: 1-5] have provided molecular links between inflammation and myoendothelial communication
Energy correlations between gamma -ray transitions and the prompt proton decay line in Cu-58 were studied by means of the fusion-evaporation reaction Ca-40(Mg-24,1 alpha 1p1n) using the EUROBALL spectrometer coupled to ancillary detector devices. A lifetime of 0.06 < tau < 0.58 ps for the 8915 keV proton-decaying state in Cu-58 is deduced. (C) 2001 Elsevier Science B.V. All rights reserved.
Objective: To evaluate the performance characteristics of direct and capture ELISA for the detection of PR3-ANCA in Wegener's granulomatosis (WG) in international ANCA reference laboratories. Methods: Serum samples were derived from patients with histological and clinical diagnosis of WG (n = 60), rheumatoid arthritis (RA) (n = 30) and healthy controls (n = 30). Each of them was tested for the pre
A multicentric phase 2 study was conducted to determine the efficiency and the tolerance of imatinib mesylate in children with chronic myelogenous leukemia (CML) in advanced phase of the disease, in relapse after stem cell transplantation, or in case of failure to an interferon a-based regimen. In all, 30 children from eight European countries were enrolled. In 18 children assessable for hematolog
Fast kicker systems are required for the proposed upgrade of ALS to a diffraction-limited light source (ALS-U). The main approach is to have multiple stripline kicker magnets driven by inductive adders. The design details of the kicker structures and the inductive adder options will be discussed.
This study investigates domestic cat vocalisations in different contexts and mental states. Measures of fundamental frequency (f0) and duration as well as f0 contours of 780 meows from 40 cats were analysed. We found significant effects of recording context and of mental state on f0 and duration. Additionally, contours in positive (affiliative) contexts and mental states were predominantly rising,
Fluid therapy is the most important component involved in the stabilization of postrenal azotemia, however there is not yet a consensus about the ideal rate of fluid therapy after relief of urethral obstruction. Fifteen adult cats were divided in two groups: High Rate Group (HRG) and Low Rate Group (LRG). At predetermined time points was assessed venous blood pH, pCO2, pO2, bicarbonate concentrati
Background: The FreeStyle Libre glucose sensor has caused many cases of allergic contact dermatitis, and isobornyl acrylate (IBOA) in this sensor has been identified as one of the culprit allergens. Objectives: To report on the presence of IBOA in devices produced by Medtronic, namely, Enlite sensor and insulin infusion set Paradigm MiniMed Quick-set. Patients and Methods: Five patients reacting t
Brain structure and function are tightly correlated across all animals. While these relations are ultimately manifestations of differently wired neurons, many changes in neural circuit architecture lead to larger-scale alterations visible already at the level of brain regions. Locating such differences has served as a beacon for identifying brain areas that are strongly associated with the ecologi
