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Associations between human non-motorised recreational activity on nest box occupation, exploratory behaviour and breeding success in a passerine bird

Anthropomorphic activities have a large impact on ecosystems in many ways, one of which is how animals behave. Non-motorised nature recreation is a popular human activity of which the impacts on nature are largely unknown. These activities, which include hiking, biking, pet walking and horseback riding, tend to increase during the commencement of the breeding activity for most passerine forest bir

Long-term relationships between climate oscillation and basin-scale hydrological variability during rainy season in eastern Northeast Brazil

The high variability in the hydrological regime of the Eastern Hydrological Region (EHR) of Northeast Brazil often results in floods and droughts, leading to serious socio-economic issues. Therefore, this work aimed to investigate connections between spatiotemporal hydrological variability of the EHR and large-scale climate phenomena. Multivariate statistical techniques were applied to relate clim

Haplotype structures and large-scale association testing of the 5 ' AMP-activated protein kinase genes PRK4A2, PRKAB1, and PRK4B1 with type 2 diabetes

AMP-activated protein kinase (AMPK) is a key molecular regulator of cellular metabolism, and its activity is induced by both metformin and thiazolidinedione antidiabetic medications. It has therefore been proposed both as a putative agent in the pathophysiology of type 2 diabetes and as a valid target for therapeutic intervention. Thus, the genes that encode the various AMPK subunits are intriguin

Ecosystem subsidies: Terrestrial support of aquatic food webs from C-13 addition to contrasting lakes

Whole-lake additions of dissolved inorganic C-13 were used to measure allochthony (the terrestrial contribution of organic carbon to aquatic consumers) in two unproductive lakes (Paul and Peter Lakes in 2001), a nutrient-enriched lake (Peter Lake in 2002), and a dystrophic lake (Tuesday Lake in 2002). Three kinds of dynamic models were used to estimate allochthony: a process-rich, dual-isotope flo

Advancing the Business and Human Rights Agenda: Dialogue, Empowerment, and Constructive Engagement

As corporations are going global, they are increasingly confronted with human rights challenges. As such, new ways to deal with human rights challenges in corporate operations must be developed as traditional governance mechanisms are not always able to tackle them. This article presents five different views on innovative solutions for the relationships between business and human rights that all b

Tyr2105Cys mutation in exon 22 of FVIII gene is a risk factor for the development of inhibitors in patients with mild/moderate haemophilia A

We report the case of a patient with mild haemophilia A, due to a Tyr2105Cys mutation in exon 22 of the C1 domain, who developed a high-titre factor VIII inhibitor (maximum titre 1600 BU) with recurrent severe haemorrhages and fatal intracranial bleeding. Based on published data, it appears that although this mutation occurs rarely in patients with mild or moderate haemophilia A, it is frequently

HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5

We previously reported that the human HER2 gene encodes the intronic microRNA mir-4728, which is overexpressed together with its oncogenic host gene and may act independently of the HER2 receptor. More recently, we also reported that the oncogenic miR-21-5p is regulated by 3′ tailing and trimming by the non-canonical poly(A) polymerase PAPD5 and the ribonuclease PARN. Here we demonstrate a dual fu

Prophylactic fenoldopam for renal protection in sepsis: a randomized, double blind, placebo-controlled pilot trial

OBJECTIVE: Acute renal failure is common in septic patients. Fenoldopam, a dopamine-1 receptor agonist, increases renal blood flow and may, therefore, reduce the risk of acute renal failure in such patients. Accordingly, we sought to determine the safety and efficacy of fenoldopam for the prevention of acute renal failure in septic patients. DESIGN: Prospective, double-blind, placebo-controlled t

Gravity water waves over constant vorticity flows: from laminar flows to touching waves

I denna uppsats studerar vi en matematisk modell av vattenvågor över djupt vatten. I synnerhet studerar vi vågor som färdas med konstant hastighet i en horisontell riktning och är likformiga i den vinkelräta horisontella riktningen. På grund av den matematiska svårigheten med den allmänna modellen är det vanligt att utgå från förenklade versioner av problemet. I denna uppsats, gör vi antaganden omIn a recent paper, Hur and Wheeler proved the existence of periodic steady water waves over an infinitely deep, two-dimensional and constant vorticity flow and subject to gravity whose profile overhangs, among which, waves whose surface touches at a point, enclosing a bubble of air. We take this further, proving the existence of a continuous curve of water waves from a laminar flow up to a touchin

Lifting with colourful sunflowers

We show that a generalization of the DAG-like query-to-communication lifting theorem, when proven using sunflowers over non-binary alphabets, yields lower bounds on the monotone circuit complexity and proof complexity of natural functions and formulas that are better than previously known results obtained using the approximation method. These include an nΩ(k) lower bound for the clique function up

Observational evidence for chemical ozone depletion over the Arctic in winter 1991-92

LONG-TERM depletion of ozone has been observed since the early 1980s in the Antarctic polar vortex, and more recently at mid-latitudes in both hemispheres, with most of the ozone loss occurring in the lower stratosphere1. Insufficient measurements of ozone exist, however, to determine decadal trends in ozone concentration in the Arctic winter. Several studies of ozone concentrations in the Arctic

Perspective on soundscapes : Verb constructions in descriptions of everyday sounds

This study explores how listeners use verb constructions to describeeveryday sounds. It considers (i) how the verb constructions provide Gestaltto events in the form of activities, processes and states, and (ii) how theconstructions correspond to different aspects of a soundscape (soundsources, acoustic properties, and listener reactions). We found that verbconstructions primarily describe sound s

Study of the production of π, K and p in pp collisions at √s = 13 TeV as a function of the Transverse Spherocity and the Relative Transverse Activity

High-energy heavy-ion collisions allow the Quark-Gluon Plasma (QGP) production and study, a state of high-density QCD matter in which quarks and gluons are no longer confined inside hadrons for a very short time. Different observables reveal an enhanced production of strange hadrons, signatures of collective effects and opacity to jets due to the QGP formation. However, collective effects and stra

Sulfonated polyethersulfone based cation exchange membranes for reverse electrodialysis under high salinity gradients

Salinity Gradient Power - Reverse Electrodialysis (SGP-RED) is a promising membrane-based technology to harvest the energy of mixing from solutions of different ionic concentration. Unfortunately, currently available commercial ion exchange membranes – being not specifically designed for RED – are far from satisfying the requirements of this operation, especially when operated with hyper-concentra

Management of aortic disease in children with FBN1-related Marfan syndrome: a joint statement from the paediatric subgroup of the European Reference Network of Vascular Diseases (VASCERN, Heritable Thoracic Aortic Disease working group) and the Association for European Paediatric and Congenital Cardiology (AEPC)

Marfan syndrome (MFS) is a hereditary connective tissue disorder with an estimated prevalence of 1:5000–1:10 000 individuals. It is a pleiotropic disease characterized by specific ocular, cardiovascular, and skeletal features. The most common cardiovascular complication is aortic root dilatation which untreated can lead to life-threatening aortic root dissection, mainly occurring in adult patients

Moisture Buffering in the Indoor Environment

Popular Abstract in Swedish Fuktbuffring i inomhusmiljön är ytmaterialens förmåga att, genom absorption och desorption, dämpa luftens fuktighetsvariationer. Fuktbuffring spelar en viktig roll i förståelsen av risker för biologisk tillväxt i ytmaterial, t.ex. mögel på väggar och husdammskvalster i sängar. Därigenom är fuktbuffring viktig ur hälsosynpunkt. Förutom hälsoaspekterna är kunskap om fuktbMoisture buffering in the indoor environment is the ability, through absorption and desorption, of surface materials to attenuate the moisture variations of the indoor air. Moisture buffering plays an important role in understanding the risks for biological growth in surface materials in the indoor environment, e.g., mold growth on walls and house dust mites in beds, and thereby also have an impac

A family history of fracture and fracture risk: a meta-analysis

The aims of the present study were to determine whether a parental history of any fracture or hip fracture specifically are significant risk factors for future fracture in an international setting, and to explore the effects of age, sex and bone mineral density (BMD) on this risk. We studied 34,928 men and women from seven prospectively studied cohorts followed for 134,374 person-years. The cohort